Results 151 to 160 of about 55,987 (250)

Post-injury use of opioid analgesics in patients with traumatic injury: A registry-based study. [PDF]

Eur J Pain
Torp HA, Skurtveit SO, Gustavsen I, Gran JM, Rosseland LA.   +4 more
europepmc   +1 more source

Beyond treatment response: Injection‐site reactions as part of the extended‐release buprenorphine experience

Addiction, EarlyView.
Julien Cabé, Georges Brousse
wiley   +1 more source

Alkalinised lidocaine as an anaesthetic before onabotulinumtoxinA injections. a randomised trial

BJU International, Volume 135, Issue 4, Page 638-647, April 2025.
Objectives To evaluate the effect of intravesical alkalinised lidocaine as an anaesthetic treatment on procedural pain during intradetrusor onabotulinumtoxinA (BTX‐A) injections for overactive bladder. Patients and Methods This single‐centre, randomised, double‐blind, placebo‐controlled two period crossover trial was conducted on women scheduled for ...
Meryam El Issaoui, Marlene Elmelund, Niels Klarskov   +2 more
wiley   +1 more source

Risk factors for bone metastasis in lung cancer and the efficacy of palliative radiotherapy and opioid analgesics in alleviating bone metastasis pain. [PDF]

Oncol Lett
Zhang Q, Qu B, Fan J, Liu C, Shan B, Chen C, Gao Y.   +6 more
europepmc   +1 more source

Psilocybin as a novel treatment for chronic pain

British Journal of Pharmacology, EarlyView.
Abstract Psychedelic drugs are under active consideration for clinical use and have generated significant interest for their potential as anti‐nociceptive treatments for chronic pain, and for addressing conditions like depression, frequently co‐morbid with pain.
Tate Askey, Reena Lasrado, Maria Maiarú, Gary J. Stephens   +3 more
wiley   +1 more source

Peptide-derived ligands for the discovery of safer opioid analgesics. [PDF]

Drug Discov Today
Eliasof A, Liu-Chen LY, Li Y.
europepmc   +1 more source

Activation of peripheral NOP receptors reduces periorbital mechanical allodynia evoked by CGRP in mice

British Journal of Pharmacology, EarlyView.
Background and Purpose Migraine is a neurovascular disorder largely mediated by calcitonin gene‐related peptide (CGRP). This study explores the role of the nociceptin/orphanin FQ (N/OFQ)–N/OFQ receptor (NOP) system in CGRP‐induced periorbital mechanical allodynia (PMA) in mice.
Chiara Sturaro, Pietro Pola, Michela Argentieri, Alessia Frezza, Matilde Marini, Francesco De Logu, Valentina Albanese, Marie Soukupova, Davide Malfacini, Nurulain T. Zaveri, Romina Nassini, Dane D. Jensen, Pierangelo Geppetti, Girolamo Calò, Chiara Ruzza   +14 more
wiley   +1 more source

The impact of opioid analgesics with concomitant antipsychotic use on pain modulation and management in internal medicine: a cross-sequential study protocol. [PDF]

Front Pain Res (Lausanne)
Grignoli N, Livoti S, Greco A, Pironi M, Noseda R, Ceschi A, Garo ML, Gabutti L.   +7 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Efficacy of Non-opioid Analgesics in the Management of Postoperative Pain After Major Abdominal Surgery: A Comprehensive Review and Meta-Analysis of Randomized Controlled Trials. [PDF]

Cureus
Ponappan B, Elkandow A, Abdelrahim MG, Rehman MU, Shaban E, Shaban A, Shaban A, Abosamak MF, Zaki HA.   +8 more
europepmc   +1 more source