Results 41 to 50 of about 87,314 (288)
PLoS ONE, 2019 PurposeTo estimate the prevalence of use of analgesics in Brazil; and to characterize this use, according to sociodemographic and health-related characteristics.MethodsA cross-sectional population-based study (National Survey on Access, Use and Promotion
Tatiane da Silva Dal Pizzol +5 more
doaj +1 more source
TREATMENT OF PAIN IN PEDIATRIC PATIENTS [PDF]
Journal of IMAB, 2016 The article clarifies that pain is a multidimensional phenomenon both in adults and children. The authors reviewed the literature and surveyed the clinical data on the management of pain in pediatric patients. The conclusion was made that pain management
Nikolay Yanev, Mila Vlaskovska
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Acute Pain, 2008 Although there is no “ideal analgesic,” scientists and clinicians alike continue to search for compounds with qualities which may approach the “ideal analgesic.” Characteristics of an “ideal” analgesic may include: the agent is a full agonist providing optimal/maximal analgesia for a wide range/variety of pain states (e.g., broad spectrum analgesic ...
openaire +2 more sources
A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia
Advanced Science, EarlyView.A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun +11 more
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Nature Communications, 2019 Tolerance and other side effects are important limitations to the use of opioids as analgesics. In this study, the authors generated mice lacking phosphorylation sites on the µ-opioid receptor to assess their contribution to the analgesic, tolerance and ...
A. Kliewer +8 more
doaj +1 more source
Trends in long-term prescribing of dependence forming medicines [PDF]
, 2019 Using patient-level primary care data to estimate the extent to which antidepressant medicines are prescribed to people continuously for long periods of time.
McManus, S. +3 more
core
Advanced Science, EarlyView.Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng +14 more
wiley +1 more source
Impact of a Mandatory Prescription Drug Monitoring Program on Prescription of Opioid Analgesics by Dentists. [PDF]
PLoS ONE, 2015 Prescription Drug Monitoring Programs (PDMP) are statewide databases that collect data on prescription of controlled substances. New York State mandates prescribers to consult the PDMP registry before prescribing a controlled substance such as opioid ...
Linda Rasubala +4 more
doaj +1 more source
Annals of Gastroenterological Surgery, EarlyView.This study compared short‐term outcomes of robot‐assisted versus laparoscopic colectomy for colon cancer using 1:1 propensity score matching. Among 218 matched pairs, robot‐assisted colectomy was associated with reduced blood loss, fewer conversions to open surgery, lower overall complication rates, and shorter hospital stays, despite longer operative ...
Akira Inoue +9 more
wiley +1 more source