Results 121 to 130 of about 66,208 (317)

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

Performance Measures of Diagnostic Codes for Detecting Opioid Overdose in the Emergency Department [PDF]

, 2016
Christopher Rowe, Eric Vittinghoff, Glenn‐Milo Santos, Emily Behar, Caitlin Turner, Phillip O. Coffin   +5 more
openalex   +1 more source

Maternal anorexia nervosa and risk of mental and neurodevelopmental morbidity in offspring

Child and Adolescent Mental Health, EarlyView.
Background Anorexia nervosa has the potential to affect fetal neurodevelopment. We examined the association between maternal anorexia nervosa and mental, substance‐related, and neurodevelopmental morbidity in offspring. Methods We conducted a retrospective cohort study of 1,269,370 children in Quebec, Canada, between 2006 and 2022.
Sam Amar, Gabriel Côté‐Corriveau, Mimi Israël, Howard Steiger, Nancy Low, Nicholas Chadi, Émilie Brousseau, Nahantara Lafleur, Nathalie Auger   +8 more
wiley   +1 more source

Trends in pediatric prescription-opioid overdoses in U.S. emergency departments from 2008-2020: An epidemiologic study of pediatric opioid overdose ED visits.

PLoS ONE
BackgroundOpioid overdose was declared a public health emergency in the United States, but much of the focus has been on adults. Child and adolescent exposure and access to unused prescription-opioid medications is a big concern.
Audrey Lu, Megan Armstrong, Robin Alexander, Eurella Vest, Jonathan Chang, Motao Zhu, Henry Xiang   +6 more
doaj   +1 more source

A review of performance assessment tools for rescuer response in opioid overdose simulations and training programs

, 2020
G. Franklin Edwards, Cassandra Mierisch, Brock Mutcheson, Kimberly Horn, Sarah Parker   +4 more
openalex   +1 more source

Systematic Review and Meta‐Analysis of Mortality in Patients With Anorexia Nervosa

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) has one of the highest mortality rates among psychiatric disorders. This systematic review and meta‐analysis examined the all‐cause mortality of AN patients compared to the general population using the standardized mortality ratio (SMR).
Eric Tsz‐Him Lai, Benjamin Lai, Corine Sau‐Man Wong, Lai‐Yi Wong, Kin‐Shing Cheng, Pak‐Wing Calvin Cheng, Lo Heidi Ka‐Ying, Gary Tse, Wai‐Chi Chan, Wing‐Chung Chang, Ka‐Fai Chung   +10 more
wiley   +1 more source

Promoting best practices for managing opioid overdoses in the field: A novel project Extension for Community Healthcare Outcomes program for first responders

, 2022
Alexander P. Oliver, Zachary W. Adams, Carol A. Ott, Jon Agley   +3 more
openalex   +1 more source

Alpha‐2‐adrenoreceptor agonists as analgesic drugs in equine medicine

Equine Veterinary Education, EarlyView.
Summary Managing pain in horses is challenging despite the availability of nonsteroidal anti‐inflammatory drugs, local anaesthetics, opioids and α2‐adrenoreceptor agonists. While α2‐agonists are widely used for sedation and restraint, their analgesic properties remain underutilised.
J. A. E. Hubbell, J. Brandly, W. W. Muir III, J. Page, K. Hopster   +4 more
wiley   +1 more source

Opioid Overdose Recognition: A Survey of Perceived Preparedness and Desire for Curricular Integration Among Current US Medical Students

Journal of Medical Education and Curricular Development
OBJECTIVES Opioid overdose deaths remain a major health issue in the United States (US). As future physicians, medical students must receive comprehensive training to recognize and manage opioid overdoses.
Lindsay Walsh, Brittany Chapman, Jennifer Carey, Kayla Loycano, Stephanie Carreiro   +4 more
doaj   +1 more source

County-level factors associated with a mismatch between opioid overdose mortality and availability of opioid treatment facilities.

PLoS ONE
BackgroundOpioid overdose deaths in the United States remain a major public health crisis. Little is known about counties with high rates of opioid overdose mortality but low availability of opioid use disorder (OUD) treatment facilities.
John G Rizk, Jannat Saini, Kyungha Kim, Uzma Pathan, Danya M Qato   +4 more
doaj   +1 more source