Results 171 to 180 of about 302,501 (282)

Targeting the Carotid Body Function With Big‐K+‐Channel Blocker ENA‐001 in Opioid‐Induced Respiratory Depression: A Scoping Review

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Opioids, most intravenous anesthetics and various illicit substances can cause fatal respiratory depression by depressing central respiratory networks. ENA‐001, a ventilatory modulator targeting the carotid bodies, has emerged as a potential countermeasure without impairing analgesia or hypnosis.
Jimmy J. Arevalo   +9 more
wiley   +1 more source

Toronto's drug policy paradox: Harm reduction sites and drug police occurrences in Toronto neighborhoods (1992–2020)

open access: yesCriminology, Volume 64, Issue 3, Page 561-586, August 2026.
Abstract Discourse around drug policy presents a stark contrast between policing and harm reduction models, sparking debates on the state's regulatory versus protective role. Canada is an ideal case to study drug policy models due to its global recognition as a leader in harm reduction alongside continued reliance on policing of drugs.
Taylor Domingos
wiley   +1 more source

Comparative Clinical Trajectories Across Cannabis‐Related and Nonsubstance‐Related Psychoses

open access: yesActa Psychiatrica Scandinavica, Volume 154, Issue 2, Page 142-152, August 2026.
ABSTRACT Background Research indicates that first‐episode psychosis (FEP) with cannabis use disorder (CUD) carries a substantial disease burden, but more granular clinical trajectories of cannabis‐related psychoses remain unclear. This study examines the clinical trajectories of first clinically diagnosed FEP&CUD and cannabis‐induced psychosis (CIP) in
Antti Mustonen   +7 more
wiley   +1 more source

Opioid overdose and cardiovascular disease-related mortality: a retrospective analysis using real-world data from the USA, 1999-2023. [PDF]

open access: yesFront Cardiovasc Med
Hemida MF   +15 more
europepmc   +1 more source

Temporal and geographical patterns of nitazene detections in drug samples and biospecimens in the United States, 2019–2024

open access: yesAddiction, Volume 121, Issue 8, Page 2019-2032, August 2026.
Abstract Background and aims Nitazenes are a novel subclass of synthetic opioids that have been increasingly implicated in the United States (US) overdose crisis. Despite their growing presence in the illicit drug supply, national trends have not been systematically evaluated.
David T. Zhu   +3 more
wiley   +1 more source

Healthcare utilization and mortality after overdose prevention site closure: A linked cohort analysis using segmented difference‐in‐differences time series

open access: yesAddiction, Volume 121, Issue 8, Page 2083-2090, August 2026.
Abstract Background and aims Evidence regarding the impacts of supervised drug consumption services (SDC) remains mixed, and few evaluations have used individual‐level, linkable health data to examine service withdrawal. In September 2024, the Red Deer overdose prevention site (OPS) in Alberta, Canada, was scheduled for closure, with operations ceasing
Nathaniel Day   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy