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Opioid and Benzodiazepine Overdose
This chapter, “Opioid and Benzodiazepine Overdose,” reviews the pathophysiology of disease state pertaining to overdose as well as the molecular mechanisms involved with drug receptor binding. It discusses common presenting signs and symptoms of opioid and benzodiazepine overdose in the context of a clinical scenario. It also discusses specific patient
Brad Eastman, Larry Field
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MMW Fortschritte der Medizin, 2019
What affects the risk of opioid overdose? Several factors influence the risk of overdose from opioids, including a person’s level of tolerance; the amount, potency, and type of the opioid taken; age; other medical conditions; and the presence of other sedating substances or medications....
Yngvild Olsen, Joshua M. Sharfstein
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What affects the risk of opioid overdose? Several factors influence the risk of overdose from opioids, including a person’s level of tolerance; the amount, potency, and type of the opioid taken; age; other medical conditions; and the presence of other sedating substances or medications....
Yngvild Olsen, Joshua M. Sharfstein
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Mechanisms of fatal opioid overdose
Addiction, 1999There has been increasing recognition of the problem of fatal opioid overdose. This review examines the pharmacological basis of respiratory depression following opioid administration. Respiration is controlled principally through medullary respiratory centres with peripheral input from chemoreceptors and other sources.
White, J., Irvine, R.
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Opioid Overdose—the Surgeon's Role
Annals of Surgery, 2018With increased focus on the potential harms of surgical opioid prescribing, surgeons should be cognizant of the risk of opioid-related adverse events in their patients, including overdose. Risk factors for overdose may be more prevalent than surgeons think, and include high current opioid use, previous or existing substance ...
Joceline V, Vu, Lewei A, Lin
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Intranasal Naloxone for Opioid Overdose
JAMAThis JAMA Insights describes indications for naloxone use in preventing opioid overdoses and benefits vs barriers to its availability following FDA approval of its availability without a prescription.
Jessica L, Taylor, Karen E, Lasser
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Opioid Overdoses in the United States
Journal of Pain & Palliative Care Pharmacotherapy, 2012The November 2011 issue of the online bulletin CDC Vital Signs posted by the Centers for Disease Control and Prevention of the U.S. Public Health Service entitled "Prescription Painkiller Overdoses in the U.S." addressed epidemiologic aspects of drug overdose deaths in the United States due to opioids.
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Management of Opioid Overdoses
2021The incidence of opioid-related deaths has increased recently, and clinicians treating patients in the intensive care unit (ICU) and emergency department (ED) must be prepared to manage opioid overdoses. Overdoses in the ICU can occur in an iatrogenic fashion, as with excessive dose administration, or surreptitiously, as commonly encountered in the ED.
Matthew Niehaus +2 more
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Containing the opioid overdose epidemic
BMJ, 2012Michael McCarthy looks at moves in Washington State to stem the rise in prescription opioid ...
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The Global Opioid Overdose Crisis
American Journal of Public Health, 2022Kenneth Rochel, de Camargo +1 more
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Substance Use & Addiction Journal
Background: Fatal opioid overdoses in the United States have rapidly increased since 1999. While several risk factors for overdose are known, the association of overdose risk perception with subsequent overdose is not well understood. Methods:
Yi-Shin Grace Chang +9 more
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Background: Fatal opioid overdoses in the United States have rapidly increased since 1999. While several risk factors for overdose are known, the association of overdose risk perception with subsequent overdose is not well understood. Methods:
Yi-Shin Grace Chang +9 more
openaire +2 more sources

