Results 171 to 180 of about 87,734 (315)

Structural Determinants of μ-Opioid Receptor Antagonism and Respiratory Liability in Phenylfentanyl Analogues. [PDF]

ACS Chem Neurosci
Li E, Kale BS, Silte AA, Lyu R, Upadhyay N, Neel LT, Reda A, Wang H, Dewey WL, Pagare PP, Zhang Y.   +10 more
europepmc   +1 more source

Evaluation of the acceptance rate of analgesic stewardship team recommendations at a metropolitan hospital network

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Background Analgesic stewardship (AGS) programs, a novel concept in Australia, aim to assess and optimise opioid and other analgesia by carrying out medication reviews and providing clinical recommendations to the treating teams. Aim This study aimed to determine the rate and extent of acceptance of AGS team recommendations among adult ...
Hatsumi Kobayashi, Jeremy Szmerling, Sam Maleki, Mahisha Thiruvasagan, Gordon Mar   +4 more
wiley   +1 more source

Analyzing the Chemical Space of Opioid Receptor Agonists and Antagonists: Insights from Computational Models. [PDF]

ACS Omega
Yu T, Anuwongcharoen N, Wang ZJ, Piacham T.   +3 more
europepmc   +1 more source

The Influence of G-Protein Coupling of the δ-Opioid Receptor on the Activity of δ-Opioid Receptor Ligands.

, 2000
There is much pharmacological evidence that suggests the existence of multiple δ-opioid receptors. However to date only one gene encoding for the receptor and no functional splice variants of the δ-opioid receptor have been reported.
Oakley, Sarah M.
core  

Hell's Itch: A Self‐Case Report

JEADV Clinical Practice, EarlyView.
ABSTRACT Hell's itch is a severely distressing dermatological condition characterized by the onset of incessant itching and intolerable pain 2–3 days post‐sunburn. It is underdiagnosed and underreported, and no definitive management framework has yet been developed.
Kai Peter Moors, Willem I. Visser
wiley   +1 more source

Identification of Subtype-Selective Binding Sites in the Opioid Receptor Family. [PDF]

J Chem Inf Model
S Gomes AA, Guillot B, Jelsch C, Giraldo J.   +3 more
europepmc   +1 more source

Ultrasound‐Guided Liposomal vs. Conventional Bupivacaine Erector Spinae Plane Block Plus Gabapentin for Postherpetic Neuralgia

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to compare efficacy and safety of ultrasound‐guided erector spinae plane block (ESPB) using liposomal (LB) versus conventional bupivacaine (CB), each plus standardized gabapentin, in patients with postherpetic neuralgia (PHN). A total of 116 PHN patients were randomized to ESPB‐LB or ESPB‐CB; both groups received standardized ...
Xia‐Jing Xu, Li‐Juan Liu, Fa‐Ming Xu, Xiang‐Yu Fang   +3 more
wiley   +1 more source

Mu Opioid Receptor mRNA and Protein Localization Across the Rat and Mouse Habenula. [PDF]

J Comp Neurol
Popat AK, Simon RC, Aoyama BB, Wokhlu A, Ehrlich AT, Harwell CC, Margolis EB.   +6 more
europepmc   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Activation dynamics of a water-soluble human mu-opioid receptor. [PDF]

J Biol Chem
Agyemang E, Van Wirt R, Walls C, Joseph TT, Tiruvadi-Krishnan S, Grothusen J, Zhang Q, Hicks A, Leite W, Osti NC, Mamontov E, O'Neill HM, Liu R, Lamichhane R.   +13 more
europepmc   +1 more source