Results 321 to 330 of about 2,594,817 (409)

Implementation of geriatric clinical decision support in the emergency department for potentially inappropriate medications

Academic Emergency Medicine, EarlyView.
Abstract Objectives The use of potentially inappropriate medications (PIMs) in older adults in the emergency department (ED) is associated with increased risk of readmissions and adverse drug reactions. We sought to assess the impact of electronic health record (EHR)‐based geriatric clinical decision support (CDS) on adherence to geriatric ...
Gina A. Elder, Kevin King, Marc Willner, Matthew J. Campbell, Baruch S. Fertel, Saket Saxena, Stephen Meldon   +6 more
wiley   +1 more source

GPER Enhances Chronic Burn Pain via PKC-Mediated Mu-Opioid Receptor Phosphorylation in the Rostral Ventromedial Medulla. [PDF]

J Pain Res
Zhu X, Zhang Y, Zhang Q, Zhang Z.
europepmc   +1 more source

A systematic review of interventions for persons living with dementia: The Geriatric ED Guidelines 2.0

Academic Emergency Medicine, EarlyView.
Abstract Background The increasing prevalence of dementia poses significant challenges for emergency department (ED) care, as persons living with dementia (PLWD) more frequently experience adverse outcomes such as delirium, prolonged stays, and higher mortality rates.
Sangil Lee, Michelle Suh, Luna Ragsdale, Justine Seidenfeld, James D. van Oppen, Lauren Lapointe‐Shaw, Carolina Diniz Hooper, James Jaramillo, Annie B. Wescott, Alexander X. Lo, Kaiho Hirata, Maura Kennedy, Lauren Cameron Comasco, Christopher R. Carpenter, Teresita M. Hogan, Shan W. Liu, Geriatric ED Guidelines Dementia Writing Group, Scott Dresden, Angel Li, Cameron J. Gettel, R. Doreen Monks   +20 more
wiley   +1 more source

Toxoplasma gondii chronic infection decreases visceral nociception through peripheral opioid receptor signaling. [PDF]

PLoS Pathog
Audibert A, Mas-Orea X, Rey L, Belloy M, Bassot E, Battut L, Marodon G, Masson F, Serino M, Cenac N, Dietrich G, Bonnart C, Blanchard N.   +12 more
europepmc   +1 more source

Severe Hyponatremia in the Emergency Department Incidence of Cerebral Edema and Risk of Osmotic Demyelination Syndrome

Academic Emergency Medicine, EarlyView.
ABSTRACT Study Objective Treatment strategies in severe hyponatremia aim at rapid sodium correction to prevent or treat cerebral edema but limit sodium rise to prevent osmotic demyelination syndrome (ODS). The true risk of edema or ODS in ED patients is unknown.
Volker Burst, Ramon Rabii, Julian Peto‐Madew, Thorsten Persigehl, Stefan Haneder, Matthias Johannes Hackl, Christoph Hüser, Moritz Trappe, Sadrija Cukoski, Kathrin Möllenhoff, Victor Suárez   +10 more
wiley   +1 more source

The Utility of Cyclodextrin for Countering μ-Opioid Receptor Drug Overdoses. [PDF]

ACS Cent Sci
Ogawa N.
europepmc   +1 more source

Cluster‐Randomized Trials in Emergency Care Research

Academic Emergency Medicine, EarlyView.
ABSTRACT Objective Cluster‐randomized trials (also called group‐randomized trials) are increasingly common in emergency care research. In such trials, groups of participants are allocated to different interventions based on naturally occurring “clusters,” such as clinics, hospitals, or emergency medical services agencies. In this methodological review,
Howard S. Kim, Jacob M. Schauer, Jody D. Ciolino   +2 more
wiley   +1 more source

Carfentanil stabilizes µ opioid receptor conformations that are ultra-efficient in inhibiting cAMP, resistant to naloxone or nalmefene but sensitive to naltrexone. [PDF]

Arch Toxicol
Endt F, Guo T, Steinritz D, Amend N, Gudermann T, Breit A.   +5 more
europepmc   +1 more source

The Financial Sustainability of Programs to Initiate Medications for Opioid Use Disorder in Emergency Department Settings

Academic Emergency Medicine, EarlyView.
ABSTRACT Background The US is experiencing an epidemic of opioid misuse and mortality. Effective treatments are available, including medications for opioid use disorders (MOUD), but they are greatly underused due to a variety of barriers. In response, some US hospitals have established programs to identify emergency department (ED) patients with opioid
Dominic Hodgkin, Cindy Parks Thomas, Margot T. Davis, Jennifer J. Wicks, Shelly F. Greenfield, Zachary F. Meisel, Constance M. Horgan   +6 more
wiley   +1 more source

Effects of a kappa opioid receptor antagonist on delayed postoperative pain recovery in a novel mouse sleep disorder model. [PDF]

Front Pain Res (Lausanne)
Ito H, Kawakami M, Yoshida M, Sugimoto S, Takazawa T.   +4 more
europepmc   +1 more source