Results 321 to 330 of about 2,542,870 (405)

Effects of pH on opioid receptor activation and implications for drug design. [PDF]

Biophys J
Stein C.
europepmc   +1 more source

Opioid Analgesia Following Pediatric Adenotonsillectomy: A Randomized Clinical Trial

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To compare the safety and efficacy of nonopioid versus opioid pain management following adenotonsillectomy (AT) among pediatric patients. Study Design An open‐label randomized controlled trial. Setting Tertiary care children's hospital. Methods Patients aged 3 to 17 years undergoing AT were eligible.
Rachel L. Whelan, Jennifer L. McCoy, Leonid Mirson, Raymond C. Maguire, Noel Jabbour, Jeffrey P. Simons, Joseph E. Dohar, Dennis J. Kitsko, Amanda L. Stapleton, Allison B.J. Tobey, Cuneyt M. Alper, Amber D. Shaffer, Zachary R. Bennett, David H. Chi   +13 more
wiley   +1 more source

Differential temporal decline of cerebral oxytocin and μ-opioid receptor density during the aging process in mice. [PDF]

Eur J Neurosci
Effah F, Nidadavolu P, de Gusmão Taveiros Silva NK, Wojtowicz M, Camarini R, Zimmer A, Bailey A.   +6 more
europepmc   +1 more source

Steroids for Pediatric Adenotonsillectomy Pain—A Prospective Multicenter Randomized Trial

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To compare postoperative caregiver‐reported pain control of two steroid regimens following pediatric adenotonsillectomy. Secondary objectives assessed differences in analgesic use, return to normal diet, caregiver calls, adverse effects, and emergency room (ER) visits. Study Design Prospective randomized pragmatic trial.
Kevin D. Pereira, Wiktoria A. Gocal, Anna V. Borodianski, Mary E. Williamson, Hengameh K. Behzadpour, Sonal Saraiya, Diego A. Preciado, Amal Isaiah   +7 more
wiley   +1 more source

<i>O</i>-Desmethyltramadol Enhanced Anti-Cancer Efficacy over Tramadol Through Non-μ-Opioid Receptor and Differential Cellular Contexts of Human Breast Cancer Cells. [PDF]

Int J Mol Sci
Wu ZS, Huang YH, Huang SM.
europepmc   +1 more source

Interindividual variability in the prevalence of OPRM1 and CYP2B6 gene variations may identify drug-susceptible populations [PDF]

, 2011
Bunten, Hannah, Liang, Wei-Jun, Osselton, David M., Pounder, Derrick   +3 more
core  

Post‐COVID‐19 condition: clinical phenotypes, pathophysiological mechanisms, pathology, and management strategies

The Journal of Pathology, EarlyView.
Abstract Post‐COVID‐19 condition (PCC), also known as long COVID, is a complex multiple organ system condition that can develop and persist for months after acute COVID‐19. PCC encompasses a wide range of symptoms, resulting in heterogeneous clinical manifestations. These manifestations likely arise from diverse underlying pathophysiological mechanisms,
Larissa E Vlaming‐van Eijk, Guolu Tang, Arno R Bourgonje, Wilfred F A den Dunnen, Jan‐Luuk Hillebrands, Harry van Goor   +5 more
wiley   +1 more source

Proton pump inhibitor concomitant use to prevent oxaliplatin‐induced peripheral neuropathy: Clinical retrospective cohort study

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, EarlyView.
Abstract Background Oxaliplatin‐induced peripheral neuropathy (OIPN) is a major clinical challenge because it leads to discontinuation of chemotherapy. Omeprazole, a proton pump inhibitor (PPI), has been shown to prevent OIPN in a rat model. Therefore, we aimed to test whether the concomitant use of a PPI reduces oxaliplatin discontinuation due to OIPN.
Keisuke Mine, Takehiro Kawashiri, Kohei Mori, Yusuke Mori, Haruna Ishida, Hibiki Kudamatsu, Shunsuke Fujita, Mayako Uchida, Takaaki Yamada, Nobuaki Egashira, Ichiro Ieiri, Satoru Koyanagi, Shigehiro Ohdo, Takao Shimazoe, Daisuke Kobayashi   +14 more
wiley   +1 more source

Gene polymorphism Mu opioid receptor & its impact on naltrexone treatment response in alcohol-dependent individuals: A pilot study from north India. [PDF]

Indian J Med Res
Quraishi R, Kumar R, Sarkar S, Rao R, Ambekar A.   +4 more
europepmc   +1 more source

Who Gets Referred to School‐Based Trauma Treatment? A Descriptive Analysis of Bounce Back and Support for Students Exposed to Trauma

Psychology in the Schools, EarlyView.
ABSTRACT This study describes one district's experience having counselors deliver, for the first time, a school‐based treatment to address student trauma symptoms. After their initial training, school counselors rated Bounce Back (K‐5th grade) and Support for Students Exposed to Trauma (5th−12th grade) as highly acceptable and anticipated a positive ...
Yourdanos Bekele, Kristin Scardamalia, Sharon A. Hoover, Cindy M. Schaeffer   +3 more
wiley   +1 more source