Results 101 to 110 of about 669,744 (345)

Promoting Awareness of the Opioid Epidemic in Rural Vermont [PDF]

open access: yes, 2017
Vermont is in the middle of an opioid epidemic. Heroin use fatalities are on the rise and the number of people in treatment for opioid use disorder in Rutland County has tripled in recent years.
Olson, Kathleen
core   +1 more source

Caenorhabditis elegans as a model system to identify therapeutics for alcohol use disorders [PDF]

open access: yes, 2019
Alcohol use disorders (AUDs) cause serious problems in society and few effective treatments are available. Caenorhabditis elegans (C. elegans) is an excellent invertebrate model to study the neurobiological basis of human behavior with a conserved, fully
Bell, Richard L.   +6 more
core   +1 more source

Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou   +2 more
wiley   +1 more source

Lead poisoning in opium abuser in Iran: A systematic review

open access: yesInternational Journal of Preventive Medicine, 2018
Substance abuse and its consequences are major health hazards in the world. Opium addiction is a common form of substance abuse in Iran. Adulteration of illegal substances in the process of production and distribution of the drug in black market with ...
Kambiz Soltaninejad, Shahin Shadnia
doaj   +1 more source

Housing, opportunities, motivation and engagement (HOME) for homeless youth at-risk for opioid use disorder: study protocol for a randomized controlled trial

open access: yesAddiction Science & Clinical Practice, 2021
Background Homeless youth experience high rates of substance use disorders, exposures to violence, mental and physical health conditions, and mortality. They have been particularly affected by the opioid crisis.
Natasha Slesnick   +14 more
doaj   +1 more source

Preclinical Evaluation of Vaccines to Treat Opioid Use Disorders: How Close are We to a Clinically Viable Therapeutic?

open access: yesCNS Drugs, 2020
The ongoing opioid crisis, now into its second decade, represents a global public health challenge. Moreover, the opioid crisis has manifested despite clinical access to three approved opioid use disorder medications: the full opioid agonist methadone ...
E. Townsend, M. Banks
semanticscholar   +1 more source

Community pharmacists' practices and perspectives on deprescribing high‐risk psychotropic medicines: National survey findings

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim To explore the practices, confidence and perspectives of community pharmacists in deprescribing high‐risk psychotropic medicines, including opioid analgesics, benzodiazepine, gabapentinoids and medicinal cannabis. Methods An anonymous, cross‐sectional national online survey was conducted between January and April 2025 among Australian community ...
Monica Jung   +5 more
wiley   +1 more source

Heroin-piracetam mixture: suggested mechanisms of action and risks of misinterpretation for drug users [PDF]

open access: yes, 2017
Piracetam is a positive allosteric modulator of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor that has been frequently used in the treatment of cognitive disorders.
Cappelletti, Simone   +4 more
core   +1 more source

Transmucosal fentanyl-related opioid use disorder in a cancer survivor

open access: yesTherapies
Pain is a common issue among patients with cancer, and opioids are frequently used for itspharmacological management. Fentanyl, a synthetic opioid, is estimated to be 50 to 100 times morepotent than morphine [1]. Transmucosal formulations of fentanyl are increasingly used to managecancer-related breakthrough pain, in combination with background opioid ...
Mezaache, Salim   +3 more
openaire   +3 more sources

Management of opioid use disorders: a national clinical practice guideline

open access: yesCanadian Medical Association Journal, 2018
[See related article at [www.cmaj.ca/lookup/doi/10.1503/cmaj.180209][2]][2] KEY POINTS Opioid use disorder is one of the most challenging forms of addiction facing the Canadian health care system, and a major contributor to the marked rises in opioid ...
J. Bruneau   +7 more
semanticscholar   +1 more source

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