Results 141 to 150 of about 669,744 (345)

Research progress on the depth of anesthesia monitoring based on the electroencephalogram

Ibrain, Volume 11, Issue 1, Page 32-43, Spring 2025.
Electroencephalogram (EEG) can noninvasive, continuous, and real‐time monitor the state of brain electrical activity, and the monitoring of EEG can reflect changes in the depth of anesthesia (DOA). The development of artificial intelligence can enable anesthesiologists to extract, analyze, and quantify DOA from complex EEG data.
Xiaolan He, Tingting Li, Xiao Wang
wiley   +1 more source

Preclinical Efficacy and Characterization of Candidate Vaccines for Treatment of Opioid Use Disorders Using Clinically Viable Carrier Proteins.

Molecular Pharmaceutics, 2018
Vaccines may offer a new treatment strategy for opioid use disorders and opioid-related overdoses. To speed translation, this study evaluates opioid conjugate vaccines containing components suitable for pharmaceutical manufacturing and compares ...
F. Baruffaldi, A. H. Kelcher, M. Laudenbach, Valeria Gradinati, Ajinkya R. Limkar, Michaela Roslawski, A. Birnbaum, A. Lees, C. Hassler, S. Runyon, Marco Pravetoni   +10 more
semanticscholar   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

BU10038 as a safe opioid analgesic with fewer side-effects after systemic and intrathecal administration in primates [PDF]

, 2019
© 2019 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.Background: The marked increase in mis-use of prescription opioids has greatly affected our society. One potential solution is to develop improved analgesics which have
Cami-Kobeci, Gerta, Czoty, Paul W., DeLoid, Heather B., Ding, Huiping, Hsu, Fang Chi, Husbands, Stephen M., Kiguchi, Norikazu, Ko, Mei Chuan, Sukhtankar, Devki D., Toll, Lawrence   +9 more
core   +5 more sources

Efficacy of energy‐based devices on episiotomy pain and healing: A systematic review and meta‐analysis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Episiotomy is a common obstetric procedure often associated with significant postpartum pain and delayed wound healing. Conventional treatments provide limited relief and might not be suitable for all women. Energy‐based therapies, including infrared irradiation and low‐level laser therapy (LLLT), a non‐thermal photo biomodulation ...
Shira Regev‐Sadeh, Chen Nahshon, Nadav Cohen, Ofer Lavie, Ariel Zilberlicht   +4 more
wiley   +1 more source

BIOME cohort: Multi‐system microbiome dynamics and clinical outcomes in massive burn injury patients

iMeta, EarlyView.
Massive burn injuries (MBIs) are associated with high mortality and disability rates, primarily due to microbial‐driven sepsis from extensive skin barrier loss and subsequent scar formation. This makes MBI a compelling model for studying multi‐system microbial dysbiosis following skin barrier destruction.
Runzhi Huang, Yixu Li, Xiaoliang Li, Xulin Chen, Gang Xu, Shurun Huang, Weixi Yang, Xiaodong Li, Haiming Xin, Jianqiang Jiao, Hui Chen, Yuguo Xie, Peng Duan, Wenjun Liu, Xiangdong Deng, Zongyu Li, Yiping Xiu, Jiansheng Zheng, Rujun Chen, Zhaohong Chen, Xingang Wang, Xiaojian Li, Gaoxing Luo, Yi Zhang, Hongyan Zhang, Shichu Xiao, Liang Xiao, Ruijin Guo, Jie Zhang, Xiaofei Ye, Hongtai Tang, Qiao Zuo, Bin Qu, Bingwei Sun, Changhong Lu, Chengliang Deng, Deyi Zheng, Geng Ji, Haisheng Li, Haizhou Yu, Hua Zhou, Jian Wu, Lanjun Nie, Lei Wang, Pihong Zhang, Qingfu Zhang, Shengwu Chao, Sisi Yang, Xianglin Ding, Xiangsheng Ding, Ying Yan, Jiangyong Shen, Yongjian Zhao, Yunchuan Pan, Yunbiao Shen, Yu Zhang, Zhihui Yao, Zhe Cheng, Jiangfan Xie, Zhigang Chu, Shijie Li, Long Xu, Xiuming Yang, Sujie Xie, Hanlin Sun, Shuyuan Xian, Dezhi Han, Maolong Dong, Chengde Xia, Peng Luo, Yongming Yao, Zhaofan Xia, Shizhao Ji   +72 more
wiley   +1 more source

Attitudes towards Complementary Medicine in Patients with Musculoskeletal Pain [PDF]

, 2018
The epidemic of opiate use-related deaths has become a public health crisis and has highlighted the potentially lethal effects of opiates. Vermont has adopted new laws to address the prescription of opiates, which has reduced the number of prescriptions ...
Vines, Caroline
core   +1 more source

Understanding Substance Use and Suicide Risk Among LGBTQ+ College Students Post‐COVID‐19

Journal of Addictions &Offender Counseling, EarlyView.
ABSTRACT This study examines the reported frequency of substance use, levels of suicide risk, and their relationships among LGBTQ+ college students (N = 192) following the COVID‐19 pandemic. Participants most commonly reported alcohol and marijuana use, and least commonly reported unprescribed prescription opioid or heroin use.
Afroze N. Shaikh, Jordan B. Westcott, Brittney N. R. Irion, Jackie Yang, Illiana R. Navarra‐Bueno, Hannah Martinson, Noah Diaz   +6 more
wiley   +1 more source

Characteristics of Opioid-Related Deaths in Ontario, Canada: Leveraging the Drug and Drug/Alcohol Related Death (DDARD) Database

International Journal of Population Data Science, 2018
Introduction Review of post-mortem toxicological results is the gold standard for identifying whether a death is opioid-related. The Drug and Drug/Alcohol Related Death (DDARD) database contains abstracted information from the Office of the Chief Coroner
Samantha Singh, Diana Martins, Wayne Khuu, Mina Tadrous, Tara Gomes, David Juurlink   +5 more
doaj   +1 more source

Integrating the Gestalt Model of Self With Psychedelic‐Assisted Psychotherapy

The Journal of Humanistic Counseling, EarlyView.
ABSTRACT This theoretical integration paper employs a conceptual analysis methodology to synthesize the Gestalt model of self‐as‐process with Psychedelic Somatic Interactional Psychotherapy (PSIP). Unlike traditional psychedelic therapy models that defer therapeutic engagement to postsession integration, PSIP emphasizes an active, directive therapeutic
Travis R. Fox
wiley   +1 more source