Results 151 to 160 of about 669,744 (345)

Medication for Opioid Use Disorder After Serious Injection-Related Infections in Massachusetts

JAMA Network Open
ImportanceSerious injection-related infections (SIRIs) cause significant morbidity and mortality. Medication for opioid use disorder (MOUD) improves outcomes but is underused. Understanding MOUD treatment after SIRIs could inform interventions to close this gap.ObjectivesTo examine rehospitalization, death rates, and MOUD receipt for individuals with ...
Kimmel, Simeon D., Walley, Alexander Y., White, Laura F., Yan, Shapei, Grella, Christine, Majeski, Adam, Stein, Michael D., Bettano, Amy, Bernson, Dana, Drainoni, Mari-Lynn, Samet, Jeffrey H., Larochelle, Marc R.   +11 more
openaire   +2 more sources

A Retrospective Analysis Into the Effect of Punch Grafts in Patients With Chronic Ulcers of the Lower Leg

JEADV Clinical Practice, EarlyView.
Punch grafting was retrospectively evaluated in patients with chronic lower leg ulcers treated at Erasmus MC between 2018 and 2023. Median pain scores significantly decreased after 6 weeks. Opioid use declined and 30% of patients no longer required analgesics. Complete wound closure was achieved in 7% of cases.
M. van Zanten, J. E. Geskes, M. M. E. Thung, P. Velthuis, C. van Montfrans   +4 more
wiley   +1 more source

Overnight Monitoring After T&A for Children Ages 24–36 Months: Is It Always Necessary?

The Laryngoscope, EarlyView.
This study aims to identify whether all children < 3 years of age require overnight admission after tonsillectomy with or without adenoidectomy. We found that 98.7% of children who were off oxygen within 3 h after surgery never went back on oxygen during the entire monitoring period.
Tyler Van Heest, Luka Bahra, Suhong Tong, Regina Hofner‐Hnotz, Norman Friedman   +4 more
wiley   +1 more source

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu, Zexin Zhu, Lauren Fields, Hua Zhang, Lingjun Li   +4 more
wiley   +1 more source

Managing Prolonged Pain After Surgery: Examining the Role of Opioids. [PDF]

, 2018
A notable minority of patients experience persistent postsurgical pain and some of these patients consequently have prolonged exposure to opioids. Risk factors for prolonged opioid use after surgery include preoperative opioid use, anxiety, substance ...
Pozek, John-Paul J., Schwenk, Eric S., Viscusi, Eugene R.   +2 more
core   +1 more source

Distinction and mutual Influences between Parkinson's Disease‐related and unrelated Chronic Pain

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Chronic pain (i.e. > 3 months) is a common nonmotor symptom in patients with Parkinson's disease (PD), but the attribution to PD is critical for further treatment. Objectives We explored the PD Pain Classification System (PD‐PCS) criteria for the diagnosis of PD‐related pain and mutual influences between PD‐related and PD‐unrelated ...
Jonathan Hunger, Florian Brugger, Georg Kägi, Jens Carsten Möller, Nathalie Hollenstein, David H. Benninger, Michele Tinazzi, Julien F. Bally, Roman Gonzenbach, Daniel Ciampi de Andrade, Santiago Perez Lloret, Veit Mylius   +11 more
wiley   +1 more source

Cognitive behaviour therapy as an evidence-based intervention for opioid use disorder: a systematic review

Journal of the Pakistan Medical Association
Objective: To explore the effectiveness of cognitive behaviour therapy as an evidence-based intervention for patients with opioid use disorder and to estimate the effect of cognitive behaviour therapy in mental health care settings.
Mafia Shahzadi, Khalid Mahmood Bhati
doaj   +1 more source

A Renal Impairment Subgroup Analysis of the Safety and Efficacy of Naldemedine for the Treatment of Opioid-Induced Constipation in Patients with Chronic Non-Cancer Pain Receiving Opioid Therapy

Journal of Pain Research, 2020
Lynn R Webster,1 Martin E Hale,2 Tadaaki Yamada,3 James E Wild4 1PRA Health Sciences, Salt Lake City, UT, USA; 2Gold Coast Research LLC, Plantation, FL, USA; 3Shionogi, Inc., Florham Park, NJ, USA; 4Upstate Clinical Research Associates, Williamsville, NY,
Webster LR, Hale ME, Yamada T, Wild JE
doaj  

Innovative Drug Delivery and Formulation Designs To Deter Drug Abuse/Misuse Related To Suicide [PDF]

, 2012
Patients with a history of abuse/misuse of pain and psychotic medications are at high risk for suicide. Novel drug delivery and formulation approaches have been explored to reduce the potential of drug abuse/misuse and to improve patient compliance. This
Zhao, Fang
core   +1 more source

Comprehensive Insights into Natural Bioactive Compounds: From Chemical Diversity and Mechanisms to Biotechnological Innovations and Applications

ChemistryOpen, EarlyView.
Natural products derived from plants, animals, fungi, bacteria, and minerals contain diverse bioactive classes such as alkaloids, flavonoids, terpenoids, saponins, tannins, and phenolics. These natural products work through different mechanisms, including ROS inhibition, NF‐κB suppression, and cytokine regulation, and exhibit wide applications across ...
Sajid Ali, Atif Ali Khan Khalil, Muhammad Saeed Akhtar, Adnan Amin, Wajid Zaman   +4 more
wiley   +1 more source