Results 181 to 190 of about 669,744 (345)

Update on the clinical use of buprenorphine: in opioid-related disorders.

Canadian family physician Medecin de famille canadien, 2012
To review the current evidence on buprenorphine-naloxone for the treatment of opioid-related disorders, with a focus on primary care settings.MEDLINE and the Cochrane Database of Systematic Reviews were searched. Evidence is mainly level I.Buprenorphine is a partial μ-opioid agonist and κ-opioid antagonist with a long half-life and less abuse potential
Simon, Ducharme, Ronald, Fraser, Kathryn, Gill   +2 more
openaire   +1 more source

Native American Pregnant and Postpartum People's Experiences of Discrimination During Perinatal Care: A Qualitative Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Indigenous pregnant and postpartum people are more likely to experience severe maternal morbidity (SMM) and mortality than non‐Indigenous groups. We sought to explore how community and societal factors, culture, and resilience impact Native American individuals' pregnancy experiences and might offer insights to address inequities in ...
Jennifer L. Murray, Heather Tanana, Torri D. Metz, Reham Perry, Elisabeth R. Kimball, Patrick Galyean, Susan Zickmund, Michael W. Varner, Michelle P. Debbink   +8 more
wiley   +1 more source

Improving drug identification in overdose death surveillance by using clinical natural language processing models

Journal of Forensic Sciences, EarlyView.
Abstract The rising rate of drug‐related deaths in the United States, largely driven by fentanyl, requires timely and accurate surveillance. However, critical overdose data are often buried in free‐text coroner reports, leading to delays and information loss when coded into ICD (International Classification of Disease)‐10 classifications.
Arthur J. Funnell, Panayiotis Petousis, Fabrice Harel‐Canada, Ruby Romero, Alex A. T. Bui, Adam Koncsol, Hritika Chaturvedi, Chelsea Shover, David Goodman‐Meza   +8 more
wiley   +1 more source

“It's such a terrible drug”: Narratives of fentanyl dealers amid the opioid overdose crisis

Criminology, EarlyView.
Abstract The fentanyl‐fueled overdose crisis is historically lethal, yet the voices of those who sell fentanyl remain understudied. While research has focused extensively on people who use drugs (PWUD), the perspectives of people who sell fentanyl (PWSF) are largely absent from academic and policy discussions. This study draws on 87 in‐depth interviews
Brittney M. Schwehr, Sandra M. Bucerius
wiley   +1 more source

Correctional officers and drug smuggling: Boundary work, horizontal surveillance, and cultural responses to drug entry

Criminology, EarlyView.
Abstract Drug entry into prisons represents a serious issue for both incarcerated people and prison staff. Although substances enter prisons in many ways, staff drug smuggling represents a consistent problem facing correctional institutions globally. We draw on 131 interviews with correctional officers (COs) working in four Western Canadian prisons to ...
William J. Schultz, Sandra M. Bucerius, Kevin D. Haggerty   +2 more
wiley   +1 more source

Toronto's drug policy paradox: Harm reduction sites and drug police occurrences in Toronto neighborhoods (1992–2020)

Criminology, EarlyView.
Abstract Discourse around drug policy presents a stark contrast between policing and harm reduction models, sparking debates on the state's regulatory versus protective role. Canada is an ideal case to study drug policy models due to its global recognition as a leader in harm reduction alongside continued reliance on policing of drugs.
Taylor Domingos
wiley   +1 more source

Slow Transit Constipation: Pathophysiological Perspectives and Management Updates

Journal of Digestive Diseases, EarlyView.
Slow transit constipation (STC) is a complex neuromuscular disorder driven by interstitial cells of Cajal (ICCs) loss and enteric neuropathy. Diagnosis relies on objective transit testing while excluding pelvic floor dysfunction. Management follows a stepwise, phenotype‐driven approach, progressing from conventional laxatives to emerging targeted ...
Athanasios Syllaios, Stavros P. Papadakos, Alexandros Ioannou, Maximos Frountzas, Dimosthenis Michelakis, Dimitrios Patsouras, Spyridon Dritsas, Manousos‐Georgios Pramateftakis, Dimitrios Schizas   +8 more
wiley   +1 more source

Drug Use After Emergency Department‐Initiated Injectable Buprenorphine: A Secondary Analysis of the ED‐INNOVATION Ancillary Safety and Feasibility Trial

Academic Emergency Medicine, EarlyView.
ABSTRACT Study Objective To characterize opioid and nonopioid drug use in the week following emergency department (ED)‐initiated extended‐release buprenorphine (XR‐BUP) treatment using both self‐reported data and urine drug screens (UDS). Methods This study uses data collected during a nonrandomized clinical trial of patients with untreated opioid use ...
Ethan Cowan, Gail D'Onofrio, Jeanmarie Perrone, Erik Anderson, James Dziura, Kathryn Hawk, Andrew Herring, Ryan McCormack, Manali Phadke, Elizabeth A. Samuels, David A. Fiellin   +10 more
wiley   +1 more source

Trajectories of medication for opioid use disorder and their impact on HIV testing among people who inject drugs in India: A longitudinal assessment of clinic‐based data

Addiction, Volume 120, Issue 4, Page 745-755, April 2025.
Abstract Aims The aim of this study was to identify longitudinal trajectories of medication for opioid use disorder (MOUD) use throughout 1 year following MOUD initiation and to examine the association of trajectory membership with HIV testing among people who inject drugs in India.
Allison M. McFall, Lakshmi Ganapathi, Mihili P. Gunaratne, Aylur K. Srikrishnan, Conjeevaram K. Vasudevan, Santhanam Anand, Sunil S. Solomon, Shruti H. Mehta, Gregory M. Lucas   +8 more
wiley   +1 more source

Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review

Addiction, EarlyView.
Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper, Francesca Small, Sam Brown, Michael Kelleher, Luke Mitcheson, James Rucker, Allan H. Young, John Marsden   +7 more
wiley   +1 more source