Results 31 to 40 of about 669,744 (345)

Prescription Opioid Use and Risk for Major Depressive Disorder and Anxiety and Stress-Related Disorders

open access: yesJAMA psychiatry, 2020
Key Points Question Does prescription opioid medication have a potentially causal role in the risk for depression and anxiety disorder? Findings In this 2-sample mendelian randomization study using genetic instruments for common pain medications, the ...
Daniel B. Rosoff, G. Smith, F. Lohoff
semanticscholar   +1 more source

Spatial Concentration of Opioid Overdose Deaths in Indianapolis: An Application of the Law of Crime Concentration at Place to a Public Health Epidemic [PDF]

open access: yes, 2019
The law of crime concentration at place has become a criminological axiom and the foundation for one of the strongest evidence-based policing strategies to date.
Carter, Jeremy G.   +2 more
core   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

open access: yesHepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman   +4 more
wiley   +1 more source

Overlapping mechanisms of stress-induced relapse to opioid use disorder and chronic pain: Clinical implications

open access: yesFrontiers in Psychiatry, 2016
Over the past two decades, a steeply growing number of persons with chronic non-cancer pain have been using opioid analgesics chronically to treat it, accompanied by a markedly increased prevalence of individuals with opioid-related misuse, opioid use ...
Udi E Ghitza
doaj   +1 more source

A primary care, multi-disciplinary disease management program for opioid-treated patients with chronic non-cancer pain and a high burden of psychiatric comorbidity [PDF]

open access: yes, 2005
BACKGROUND: Chronic non-cancer pain is a common problem that is often accompanied by psychiatric comorbidity and disability. The effectiveness of a multi-disciplinary pain management program was tested in a 3 month before and after trial.
A Rosenblum   +95 more
core   +4 more sources

Health disparities in chronic liver disease

open access: yesHepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian   +3 more
wiley   +1 more source

Impact of opioid dose escalation on the development of substance use disorders, accidents, self-inflicted injuries, opioid overdoses and alcohol and non-opioid drug-related overdoses: a retrospective cohort study.

open access: yesAddiction, 2020
AIM To understand the potential harmful effects of dose escalation among patients with chronic, non-cancer pain (CNCP) on chronic opioid therapy. DESIGN Retrospective cohort study.
C. Hayes   +5 more
semanticscholar   +1 more source

Role of Nociceptin/Orphanin FQ-NOP Receptor System in the Regulation of Stress-Related Disorders

open access: yesInternational Journal of Molecular Sciences, 2021
Nociceptin/orphanin FQ (N/OFQ) is a 17-residue neuropeptide that binds the nociceptin opioid-like receptor (NOP). N/OFQ exhibits nucleotidic and aminoacidics sequence homology with the precursors of other opioid neuropeptides but it does not activate ...
M. Ubaldi   +9 more
semanticscholar   +1 more source

Opioid Use Disorder in Women and the Implications for Treatment

open access: yesPsychiatric Research and Clinical Practice, 2021
Objective The opioid epidemic continues to evolve and impact all groups of people. Moreover, there are concerning trends among women. The aim of this article is to provide a review of opioid use disorder in women and the implications for treatment ...
Celestina Barbosa‐Leiker   +4 more
doaj   +1 more source

Neurobehavioral consequences of chronic intrauterine opioid exposure in infants and preschool children: a systematic review and meta-analysis [PDF]

open access: yes, 2014
<b>Background</b><p></p> It is assumed within the accumulated literature that children born of pregnant opioid dependent mothers have impaired neurobehavioral function as a consequence of chronic intrauterine opioid use.<p>&
A Baldacchino   +86 more
core   +12 more sources

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