Results 1 to 10 of about 14,759,288 (215)

Opioid use disorder [PDF]

Nature Reviews Disease Primers, 2020
Opioid use disorder (OUD) is a chronic relapsing disorder that, whilst initially driven by activation of brain reward neurocircuits, increasingly engages anti-reward neurocircuits that drive adverse emotional states and relapse. However, successful recovery is possible with appropriate treatment, although with a persisting propensity to relapse.
Strang, John, Volkow, Nora D., Degenhardt, Louisa, Hickman, Matthew, Johnson, Kimberly, Koob, George F., Marshall, Brandon D.L., Tyndall, Mark, Walsh, Sharon L.   +8 more
openaire   +5 more sources

An Effective and Safe Novel Treatment of Opioid Use Disorder: Unilateral Transcranial Photobiomodulation

Frontiers in Psychiatry, 2021
Background: The opioid epidemic is a global tragedy even with current treatments, and a novel, safe, and effective treatment would be welcomed. We report here our findings from our second randomized controlled trial to evaluate unilateral transcranial ...
Fredric Schiffer, Fredric Schiffer, Fredric Schiffer, Alaptagin Khan, Alaptagin Khan, Elizabeth Bolger, Edward Flynn, William P. Seltzer, Martin H. Teicher, Martin H. Teicher   +9 more
doaj   +1 more source

Naloxone protection, social support, network characteristics, and overdose experiences among a cohort of people who use illicit opioids in New York City

Harm Reduction Journal, 2022
Background Despite increased availability of take-home naloxone, many people who use opioids do so in unprotected contexts, with no other person who might administer naloxone present, increasing the likelihood that an overdose will result in death. Thus,
Alex S. Bennett, Joy Scheidell, Jeanette M. Bowles, Maria Khan, Alexis Roth, Lee Hoff, Christina Marini, Luther Elliott   +7 more
doaj   +1 more source

Prevalence and predictors of suicidality among adults initiating office-based buprenorphine

Addiction Science & Clinical Practice, 2023
Background Individuals who have substance use disorders may have an elevated risk of suicidality. This study sought to examine the prevalence of, and identify factors associated with, suicidality in adults with opioid use disorder (OUD) initiating office-
Michelle R. Lent, Karen L. Dugosh, Emily Hurstak, Hannah R. Callahan, Kimberly Mazur, The Greater Philadelphia Opioid Use Disorder Research Group   +5 more
doaj   +1 more source

Opioid use and disposal patterns of emergency department patients

Journal of Emergencies, Trauma and Shock, 2023
Introduction: To date, there is limited literature to guide emergency providers (EPs) on the proper dosing of prescription opioids. Our study aims to assess the self-reported opioid use, storage, and disposal practices of patients presenting to the ...
Valerie Hoerster, Derek Tang, Marlee Milkis, Stephanie Litzenberger, Jill Stoltzfus, Holly Stankewicz   +5 more
doaj   +1 more source

“I'm putting a Band-Aid on a bullet hole the only way I know how:” a qualitative study of barriers and facilitators to opioid misuse and recovery in Nevada

Substance Abuse Treatment, Prevention, and Policy, 2022
Nevada, like the rest of the United States, is undergoing substantial challenges with opioid misuse and overdose deaths, further exacerbated by the COVID-19 pandemic.
Tessa Swigart, Lisa Lee
doaj   +1 more source

Racial/ethnic disparities in opioid overdose prevention: comparison of the naloxone care cascade in White, Latinx, and Black people who use opioids in New York City

Harm Reduction Journal, 2023
Background Drug overdose mortality is rising precipitously among Black people who use drugs. In NYC, the overdose mortality rate is now highest in Black (38.2 per 100,000) followed by the Latinx (33.6 per 100,000) and white (32.7 per 100,000) residents ...
Maria R. Khan, Lee Hoff, Luther Elliott, Joy D. Scheidell, John R. Pamplin, Tarlise N. Townsend, Natalia M. Irvine, Alex S. Bennett   +7 more
doaj   +1 more source

Methadone for Opioid Use Treatment during Pregnancy: Trends in Postpartum Dose Adjustments

American Journal of Perinatology Reports, 2020
Objective This study examines methadone dose adjustment postpartum. Methods A retrospective study of women with methadone for opioid use treatment (OUT) during pregnancy was performed.
Clara Ward, Carl W. Christensen
doaj   +1 more source

Syndemic factors associated with non-fatal overdose among young opioid users in New York City

Frontiers in Public Health, 2023
IntroductionRates of illicit opioid use are particularly high among young adults, yet research on overdose experience and factors associated with overdose in this population remains limited. This study examines the experiences and correlates of non-fatal
Honoria Guarino, David Frank, Kelly Quinn, Kelly Quinn, Dongah Kim, Krista Gile, Kelly Ruggles, Samuel R. Friedman, Pedro Mateu-Gelabert   +8 more
doaj   +1 more source

Preadmission Opioid Use and 1‐Year Mortality Following Incident Myocardial Infarction: A Danish Population‐Based Cohort Study (1997–2016)

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Opioid use has been linked to an increased risk of myocardial infarction and cardiovascular mortality, but the prognostic impact of opioid use before an incident myocardial infarction is largely unknown.
Søren Korsgaard, Troels Munch, Erzsébet Horváth–Puhó, Kasper Adelborg, Christian Fynbo Christiansen, Lars Pedersen, Morten Schmidt, Henrik Toft Sørensen   +7 more
doaj   +1 more source