Results 21 to 30 of about 14,759,288 (215)

Opioids and Chronic Pain: An Analytic Review of the Clinical Evidence

Frontiers in Pain Research, 2021
We conducted an analytic review of the clinical scientific literature bearing on the use of opioids for treatment of chronic non-cancer pain in the United States.
Stephen E. Nadeau, Jeffrey K. Wu, Richard A. Lawhern   +2 more
doaj   +1 more source

Impact of Medical Marijuana Legalization on Opioid Use, Chronic Opioid Use, and High-risk Opioid Use [PDF]

Journal of General Internal Medicine, 2019
To determine the association of medical marijuana legalization with prescription opioid utilization.A 10% sample of a nationally representative database of commercially insured population was used to gather information on opioid use, chronic opioid use, and high-risk opioid use for the years 2006-2014.
Anuj, Shah, Corey J, Hayes, Mrinmayee, Lakkad, Bradley C, Martin   +3 more
openaire   +2 more sources

Risk of Postpartum Opioid Use Disorder or Opioid Overdose After Prenatal Opioid Analgesic Use

Obstetrics & Gynecology, 2021
Risk of postpartum opioid use disorder or overdose is low among women with prenatal opioid analgesic use.
Camden, Andi, Guttmann, Astrid, Li, Wenbin, Velez, Maria P., Brogly, Susan B.   +4 more
openaire   +3 more sources

A Brief Screening Tool for Opioid Use Disorder: EMPOWER Study Expert Consensus Protocol

Frontiers in Medicine, 2021
Growing concerns about the safety of long-term opioid therapy and its uncertain efficacy for non-cancer pain have led to relatively rapid opioid deprescribing in chronic pain patients who have been taking opioid for years.
Dokyoung S. You, Aram S. Mardian, Aram S. Mardian, Beth D. Darnall, Chwen-Yuen A. Chen, Korina De Bruyne, Pamela D. Flood, Ming-Chih Kao, Anita D. Karnik, Jennifer McNeely, Joel G. Porter, Robert P. Schwartz, Richard L. Stieg, Sean C. Mackey   +13 more
doaj   +1 more source

Ligand-Specific Regulation of the Endogenous Mu-Opioid Receptor by Chronic Treatment with Mu-Opioid Peptide Agonist [PDF]

, 2013
Since the discovery of the endomorphins (EM), the postulated endogenous peptide agonists of the mu-opioid receptors, several analogues have been synthesized to improve their binding and pharmacological profiles.
Murányi Marianna, Szűcs, Mária, Dochnal Roberta, Kicsi Emese, Kicsi, Emese Gabriella, Fábián Gabriella, Szabó Gyula, Szabó, Gyula, Zentai, András, Bozó, Beáta, Fábián, Gabriella, Birkás Erika, Cinar Resat, Bozó Bea, Birkás, Erika, Kékesi Orsolya Sára, Cinar, Resat, Tóth, Géza, Mácsai Mónika, Mácsai, Mónika, Kékesi, Orsolya, Dochnal, Roberta Beatrix, Tóth Géza, Szűcs Mária, Murányi, Marianna, Zentai András   +25 more
core   +2 more sources

Virally Suppressed People Living with HIV Who Use Opioids Have Diminished Latency Reversal

Viruses, 2023
Of the 12 million people who inject drugs worldwide, 13% live with HIV. Whether opioid use impacts HIV pathogenesis and latency is an outstanding question. To gain insight into whether opioid use influences the proviral landscape and latent HIV reservoir,
Binita Basukala, Sarah Rossi, Sally Bendiks, Natalia Gnatienko, Gregory Patts, Evgeny Krupitsky, Dmitry Lioznov, Kaku So-Armah, Manish Sagar, Christine Cheng, Andrew J. Henderson   +10 more
doaj   +1 more source

Family member opioid prescriptions and opioid use disorder [PDF]

Addictive Behaviors, 2019
It is recognized that family members are a major source of diverted opioids. Yet it is not known how family member opioid prescriptions predict the development of an opioid use disorder (OUD).We conducted an observational study using commercial health care claims to investigate the association between a family member opioid prescription and an ...
Mir M. Ali, Rachel Mosher Henke, Ryan Mutter, Peggy L. O'Brien, Eli Cutler, Maryann Mazer-Amirshahi, Jesse M. Pines   +6 more
openaire   +2 more sources

Efficacy of motivational-interviewing and guided opioid tapering support for patients undergoing orthopedic surgery (MI-Opioid Taper): A prospective, assessor-blind, randomized controlled pilot trial

EClinicalMedicine, 2020
Background: Postoperative opioid use can lead to chronic use and misuse. Few studies have examined effective approaches to taper postoperative opioid use while maintaining adequate analgesia.
Jennifer M. Hah, Jodie A. Trafton, Balasubramanian Narasimhan, Partha Krishnamurthy, Heather Hilmoe, Yasamin Sharifzadeh, James I. Huddleston, Derek Amanatullah, William J. Maloney, Stuart Goodman, Ian Carroll, Sean C. Mackey   +11 more
doaj   +1 more source

Impact of acute intoxication on quantitative pupillometry assessment in the emergency department

Journal of the American College of Emergency Physicians Open, 2022
Study Hypothesis/Objective This prospective cohort study aimed to assess whether and to what extent different quantitative pupillometry (QP) metrics are associated with different intoxicant drug classes as well as investigate the potential benefit of QP ...
Eliana L. Jolkovsky, Felix E. Fernandez‐Penny, Maya Alexis, Lauren N. Benson, Bo Hwan Wang, Benjamin S. Abella   +5 more
doaj   +1 more source

Perspectives from Systems-Level Key Informants on Optimizing Opioid Use Disorder Treatment for Adolescents and Young Adults

Children
Background/Objectives: Rates of receiving opioid use disorder (OUD) treatment among adolescents and young adults (AYA) aged 16–25 are low. The current study qualitatively analyzed informants’ perspectives regarding the availability of, developmental ...
Jasper Yeh, Crosby Modrowski, Isabel Aguirre, Samantha Portis, Robert Miranda, Melissa Pielech   +5 more
doaj   +1 more source