Results 231 to 240 of about 1,408,984 (372)

Landscape of informed consent practices and challenges in point‐of‐care clinical trials

open access: yesLearning Health Systems, EarlyView.
Abstract Point‐of‐care trials, an approach to trial design that assesses medical product effectiveness while fully integrating research and care, represent a promising opportunity to generate practically relevant evidence efficiently for priority disease areas.
Caleigh Propes   +2 more
wiley   +1 more source

Empirical calibration of a simulation model of opioid use disorder. [PDF]

open access: yesPLoS One
Madushani RWMA   +5 more
europepmc   +1 more source

Aligning forces to accelerate healthcare transformation: Insights from the UPMC learning community

open access: yesLearning Health Systems, EarlyView.
Abstract Introduction To accelerate transformation toward value‐based, equitable care, health systems need a viable approach for engaging and aligning multiple stakeholders to promote innovation. Building and sustaining learning communities offers one possible solution.
Diane Holder   +5 more
wiley   +1 more source

A learning health system model for addressing substance use: Denver Health Center for Addiction Medicine

open access: yesLearning Health Systems, EarlyView.
Abstract Introduction Substance use disorders (SUDs) continue to place heavy burdens on patients, health systems, and communities. Rapidly evolving treatment for SUDs requires health systems that can efficiently and effectively assess data and integrate evidence to practice.
Emily Bacon   +8 more
wiley   +1 more source

Delirium‐associated medication in people at risk: A systematic update review, meta‐analyses, and GRADE‐profiles

open access: yesActa Psychiatrica Scandinavica, Volume 147, Issue 1, Page 16-42, January 2023., 2023
Abstract Background Drug‐associated delirium is a common but potentially preventable neuropsychiatric syndrome associated with detrimental outcomes. Empirical evidence for delirium‐associated medication is uncertain due to a lack of high‐quality studies.
Michael Reisinger   +4 more
wiley   +1 more source

Antagonist Treatment for Opioid Use Disorder [PDF]

open access: yesThe American Journal of Medicine, 2017
Bernard L. Silverman, Sarah C. Akerman
openaire   +3 more sources

Disentangling informing participants from obtaining their consent

open access: yesLearning Health Systems, EarlyView.
Abstract Introduction Pragmatic clinical trials conducted in the context of routine care frequently satisfy the regulatory criteria for a waiver of research consent. When they do, investigators and Institutional Review Boards might assume that there is no reason to communicate any information regarding the study to participants.
Patricia Pearl O'Rourke   +15 more
wiley   +1 more source

Toward staging differentiation for posttraumatic stress disorder treatment

open access: yesActa Psychiatrica Scandinavica, Volume 147, Issue 1, Page 65-80, January 2023., 2023
Abstract Objectives Several medical and psychiatric disorders have stage‐based treatment decision‐making methods. However, international treatment guidelines for posttraumatic stress disorder (PTSD) fail to give specific treatment recommendations based on chronicity or stage of the disorder.
Mirjam J. Nijdam   +2 more
wiley   +1 more source

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