Results 81 to 90 of about 75,991 (302)

Stratified analyses of genome wide association study data reveal haplotypes for a candidate gene on chromosome 2 (KIAA1211L) is associated with opioid use in patients of Arabian descent

BMC Psychiatry, 2020
Background Genome Wide Association Studies (GWAS) have been conducted to identify genes and pathways involved in development of opioid use disorder. This study extends the first GWAS of substance use disorder (SUD) patients from the United Arab Emirates (
Hiba Alblooshi, Habiba Al Safar, Ahmed El Kashef, Hamad Al Ghaferi, Mansour Shawky, Gary K. Hulse, Guan K. Tay   +6 more
doaj   +1 more source

Influence of Psychiatric Comorbidities on Postoperative Outcomes Following Pediatric Medial Patellofemoral Ligament Reconstruction

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To compare postoperative complications, rehabilitation outcomes, and health care utilization in children undergoing primary medial patellofemoral ligament reconstruction for patellofemoral instability with and without a pre‐existing mental illness. Methods The TriNetX U.S.
Haad A. Arif, Pearce Lane, Shamar T. Elliott, Amit Momaya, Kevin A. Williams   +4 more
wiley   +1 more source

Loss of Reduction and Clavicle Fractures Commonly Occur in Patients Undergoing Acromioclavicular Joint Reconstruction and Female Sex Is Associated With Higher Fracture Risk

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To use a large, multi‐institutional database to characterize the outcomes and complication profile after primary acromioclavicular (AC) joint reconstruction and to evaluate potential sex‐related differences in outcomes and complications. Methods The TriNetX national database was queried for patients undergoing AC joint reconstruction between ...
Scott Fong, Arthur Saroyan, Rajiv S. Vasudevan, Michael S. Lee, Louise A. Atadja, Peter F. Monahan, Jay Moran, Kevin Girardi, Jacob D. Kodra, Jonathan Salandra, Andrew E. Jimenez   +10 more
wiley   +1 more source

Precision medicine in paediatrics: Progress and priorities

British Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain, Claire Booth, Joseph F. Standing, Charlotte I. S. Barker   +3 more
wiley   +1 more source

Best practices across the continuum of care for the treatment of opioid use disorder. [PDF]

, 2018
People living with an opioid use disorder in Canada should have access to comprehensive treatment options that meet all their needs. Best Practices across the Continuum of Care for the Treatment of Opioid Use Disorder presents services that should be ...
Taha, Sheena
core  

271 Evaluation of treatment for opioid use disorder across North Carolina: a study protocol

Journal of Clinical and Translational Science
OBJECTIVES/GOALS: Our objectives are to: 1) characterize opioid treatment providers in North Carolina according to payment methods accepted and ability to provide medications for opioid use disorder and 2) use geomapping technology to characterize ...
Rachel Lynn Graves, Janine Short, Erin W. Barnes, Jason Stopyra   +3 more
doaj   +1 more source

Exploring new avenues: Psychedelic‐assisted therapy for young people

British Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou, Dasha Nicholls, David J. Nutt, Martina Di Simplicio   +3 more
wiley   +1 more source

Perspectives of substance use disorder counselors on the benefits and drawbacks of medications for opioid use disorder

Addiction Science & Clinical Practice
Background Medications for opioid use disorder (MOUD) are among the best tools available to combat the opioid epidemic. Yet, use of MOUD among people with opioid use disorder (OUD) remains low.
Nicholas C. Cardamone, Rebecca E. Stewart, Kyle M. Kampman, Steven C. Marcus   +3 more
doaj   +1 more source

The Substance Use Treatment and Recovery Team (START) study: protocol for a multi-site randomized controlled trial evaluating an intervention to improve initiation of medication and linkage to post-discharge care for hospitalized patients with opioid use disorder

Addiction Science & Clinical Practice, 2022
Background People with opioid use disorder experience high burden of disease from medical comorbidities and are increasingly hospitalized with medical complications.
Allison J. Ober, Cristina Murray-Krezan, Kimberly Page, Peter D. Friedmann, Karen Chan Osilla, Stephen Ryzewicz, Sergio Huerta, Mia W. Mazer, Isabel Leamon, Gabrielle Messineo, Katherine E. Watkins, Teryl Nuckols, Itai Danovitch   +12 more
doaj   +1 more source

Development of a nalmefene formulation suitable for a community‐use auto‐injector

British Journal of Clinical Pharmacology, EarlyView.
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano, Manjunath S. Shet, Hugh Huang, Ronnie Ortiz, Garth T. Whiteside, Glen Apseloff, Stephen C. Harris   +6 more
wiley   +1 more source