Harm Reduction JournalBackground Illicit opioids, including fentanyl, are linked to unprecedented levels of overdose in Canada and elsewhere. The risks associated with illicit opioids can include high potency, unpredictable concentration and the unexpected presence in other ...
Bruce Wallace +12 more
doaj +1 more source
Status and Rationality of Opioid Use in Lung Cancer Patients: A Single Center Retrospective Study
Chinese Journal of Lung Cancer, 2020 Background and objective Cancer pain affect the physical activity, psychological state and quality of life seriously, and even shortened the survival time of patients.
Wenjuan SUN +4 more
doaj +1 more source
Retrospective analysis reveals significant association of hypoglycemia with tramadol and methadone in contrast to other opioids. [PDF]
, 2019 Tramadol is one of the most commonly used analgesics worldwide, classified as having a low abuse potential by U.S. Drug Enforcement Agency, and often recommended in pain management guidelines.
Abagyan, Ruben +3 more
core +1 more source
Academic Forensic Pathology, 2017 In recent years, there has been a substantial increase in opioid use and abuse, and in opioid-related fatal overdoses. The increase in opioid use has resulted at least in part from individuals transitioning from prescribed opioids to heroin and fentanyl, which can cause significant respiratory depression that can progress to apnea and death. Heroin and
openaire +2 more sources
Morphine for the Treatment of Pain in Sickle Cell Disease
The Scientific World Journal, 2015 Pain is a hallmark of sickle cell disease (SCD) and its treatment remains challenging. Opioids are the major family of analgesics that are commonly used for treating severe pain.
Mihir Gupta +3 more
doaj +1 more source
The dark side of opioids in pain management: basic science explains clinical observation
PAIN Reports, 2016 . Introduction:. In the past 2 decades, opioids have been used increasingly for the treatment of persistent pain, and doses have tended to creep up. As basic science elucidates mechanisms of pain and analgesia, the cross talk between central pain and ...
Cyril Rivat, Jane Ballantyne
doaj +1 more source
ATHENA: A Phase 3, Open-Label Study Of The Safety And Effectiveness Of Oliceridine (TRV130), A G-Protein Selective Agonist At The µ-Opioid Receptor, In Patients With Moderate To Severe Acute Pain Requiring Parenteral Opioid Therapy. [PDF]
, 2019 Background:Pain management with conventional opioids can be challenging due to dose-limiting adverse events (AEs), some of which may be related to the simultaneous activation of β-arrestin (a signaling pathway associated with opioid-related AEs) and G ...
Beard, Timothy L +10 more
core
The biopsychology of maternal behavior in nonhuman mammals [PDF]
, 1990 The term “maternal behavior,” when applied to nonhuman mammals, includes the behaviors exhibited in preparation for the arrival of newborn, in the care and protection of the newly arrived young, and in the weaning of those young, and represents a complex
Kristal, Dr. Mark B.
core
Opioid Analgesic Prescribing Practices of Dental Professionals in the United States [PDF]
, 2017 The prescription of opioid analgesics by dental professionals is widespread in the United States. Policy makers, government agencies, and professional organizations consider this phenomenon a growing public health concern.
Okunseri, Christopher +4 more
core +2 more sources
Outlook Magazine, Autumn 2017 [PDF]
, 2017 https://digitalcommons.wustl.edu/outlook/1202/thumbnail ...
core +1 more source