Results 61 to 70 of about 181,981 (311)

Place‐based risk: Examining relationships between adolescent perceptions of community risk factors and adolescent substance use across geographic contexts

American Journal of Community Psychology, EarlyView.
Abstract Mixed evidence for the influence of structural and social factors on adolescent substance use behaviors exists across the rural–urban continuum. Therefore, this study explores how adolescent perceptions of structural and social community risk factors are associated with lifetime and past 30‐day use of alcohol, marijuana, cigarettes, and ...
Melissa Pearman Fenton, Sarah D. Lynne, Josie L. Bryan, Catherine Woodstock Striley, Larry F. Forthun   +4 more
wiley   +1 more source

Trends in Opioid‐Related Poisonings and Mental and Behavioral Disorders From 2006 to 2022 Among a Large Cohort of Injured Workers in Ontario, Canada

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Work‐related injuries may increase risk for opioid‐related harms. Yet there remains a gap in our understanding of trends in opioid‐related harms over time among injured workers. We estimated trends in hospital encounters for opioid‐related harms among injured workers in Ontario, Canada from 2006 to 2022.
Jeavana Sritharan, Chaojie Song, Paul A. Demers, Fateme Kooshki, Nancy Carnide   +4 more
wiley   +1 more source

Association of Opioids and Sedatives with Increased Risk of In-Hospital Cardiopulmonary Arrest from an Administrative Database. [PDF]

PLoS ONE, 2016
BACKGROUND:While opioid use confers a known risk for respiratory depression, the incremental risk of in-hospital cardiopulmonary arrest, respiratory arrest, or cardiopulmonary resuscitation (CPRA) has not been studied.
Frank J Overdyk, Oonagh Dowling, Joseph Marino, Jiejing Qiu, Hung-Lun Chien, Mary Erslon, Neil Morrison, Brooke Harrison, Albert Dahan, Tong J Gan   +9 more
doaj   +1 more source

Opioids in clinical practice [PDF]

, 2020
The treatment of pain improves quality of life. Opioids are commonly prescribed painkillers. The side effectsof opioids depend on the route of administration, dosage, drug metabolism, comorbid diseases and thepatient’s general condition.
Perlińska, Maria; Students' Scientific Society, Poznan University of Medical Sciences, Poznan, Poland, Woźniak, Martyna; Students' Scientific Society, Poznan University of Medical Sciences, Poznan, Poland, Gorzelinska, Lidia; Palliative Medicine In-Patient Unit, University Hospital of Lord’s Transfiguration, Poznan University of Medical Sciences, Os. Rusa 55, 61-245 Poznan, Poland, Zaporowska-Stachowiak, Iwona; Chair and Department of Palliative Medicine, Pharmacotherapy in Palliative Care Laboratory, Poznan University of Medical Sciences, University Clinical Hospital, Poznan, Poland; Palliative Medicine In-Patient Unit, University Hospital of Lord’s Transfiguration, Poznan University of Medical Sciences, Os. Rusa 55, 61-245 Poznan, Poland, Dziuba, Gabriela; Students' Scientific Society, Poznan University of Medical Sciences, Poznan, Poland, Mikołajczak, Anna; Students' Scientific Society, Poznan University of Medical Sciences, Poznan, Poland, Oduah, Mary-Tiffany Adannia; English Students’ Research Association, Poznan University of Medical Sciences, Jackowskiego 41, 60-512 Poznan, Poland, Celichowska, Magdalena; Students' Scientific Society, Poznan University of Medical Sciences, Poznan, Poland, Sopata, Maciej; Palliative Medicine In-Patient Unit, University Hospital of Lord’s Transfiguration, Poznan University of Medical Sciences, Os. Rusa 55, 61-245 Poznan, Poland   +8 more
core   +1 more source

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen, Kristin Ørstavik, Unni Steen, Mathias Toft, Cathrine Brunborg, Lena Lande Wekre   +5 more
wiley   +1 more source

Recommendations for the use of opioids in Brazil: Part III. Use in special situations (postoperative pain, musculoskeletal pain, neuropathic pain, gestation and lactation)

Revista Dor, 2014
BACKGROUND AND OBJECTIVES: The use of opioids as first and second line agents to adequately treat pain requires systematization in different clinical syndromes which course with acute pain.
Durval Campos Kraychete, José Tadeu Tesseroli de Siqueira, Telma Regina Mariotto Zakka, João Batista Santos Garcia   +3 more
doaj   +2 more sources

Adipose‐derived mesenchymal stem cell injection into the KI10 acupoint mitigates cartilage damage in KOA rats through PGE2‐mediated α7nAChR/NF‐κB pathway

Animal Models and Experimental Medicine, EarlyView.
In our research, KOA rat models were established and treated with ADSC injection into the KI10 acupoint. Pain relief, behavioral function, and joint structural improvements were systematically assessed using ethological tests, imaging, histopathological staining, transmission electron microscopy, and molecular analyses.
Mengwei Dong, Wenfang Li, Wanpeng Yang, Te Ba, Nan Nan, Yang Liu, Jing Han, Huiqin Hao   +7 more
wiley   +1 more source

Neuropsychiatric manifestations due to anticholinergic agents and anabolic steroids ingestion: A case series and literature review

Neuropsychopharmacology Reports
Anticholinergic toxicity is a common occurrence in the emergency room, making it crucial for emergency clinicians to have a good understanding of this toxidrome.
Homa Talabaki, Mahkameh Soltani, Ali Abbasi, Vahid Sharifi, Narges Salehi, Zakaria Zakariaei   +5 more
doaj   +1 more source

Neurotransmitter‐Defined Degeneration Patterns in Sporadic and C9orf72‐Associated Amyotrophic Lateral Sclerosis: Predilection to GABAergic, Serotonergic, Opioid, Glutamatergic, Endocannabinoid, and Microglial Systems—Implications for Therapy Development

Annals of Neurology, EarlyView.
Objective Amyotrophic lateral sclerosis (ALS) has a markedly distinctive clinical and neuroradiological signature, with the preferential involvement of specific brain networks and the apparent sparing of others. The molecular underpinnings of the strikingly selective anatomical vulnerability have not been fully elucidated to date despite the potential ...
Marlene Tahedl, We Fong Siah, Jasmin Lope, Jennifer C. Hengeveld, Mark A. Doherty, Russell L. McLaughlin, Orla Hardiman, Ee Ling Tan, Alison Toomey, Jana Kleinerova, Peter Bede   +10 more
wiley   +1 more source

Morphine for the Treatment of Pain in Sickle Cell Disease

The Scientific World Journal, 2015
Pain is a hallmark of sickle cell disease (SCD) and its treatment remains challenging. Opioids are the major family of analgesics that are commonly used for treating severe pain.
Mihir Gupta, Lilian Msambichaka, Samir K. Ballas, Kalpna Gupta   +3 more
doaj   +1 more source