Results 51 to 60 of about 241,172 (309)

A Background of the Opioid Epidemic and Its Relationship to the Medicaid Expansion [PDF]

, 2019
Despite the recent increase in public awareness of the opioid epidemic, the background of this epidemic is still disappointingly unknown to the public.
Jang, Er Yearn
core   +2 more sources

Circular RNA circNrip1 Interacts with SYNCRIP to Promote Neuropathic Pain by Stabilizing Tlr2 mRNA in Primary Sensory Neurons

Advanced Science, EarlyView.
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng, Jifang Xiao, Congcong Huang, Bao‐Chun Jiang, Bing Wang, Xu Li, Shibin Du, Tolga Berkman, Chun‐Hsien Wen, Weihua Cai, Dilip Sharma, Kun Wang, Longfei Ma, Huijuan Hu, Yuan‐Xiang Tao   +14 more
wiley   +1 more source

Ergotamine/Caffeine Overdose in a Female Suffering From Migraine Headache: A Case Report [PDF]

Pharmaceutical and Biomedical Research
Background: Ergotamine is a very common antimigraine and is widely used in the management of headaches such as cluster and acute migraines. However, Ergotamine poisoning is an infrequent condition, and there are very few cases reported.
Amir Hasan Farzaneh, Navid Khosravi
doaj  

Chronic Pain Management With Opioids: An Assessment of Alaska Nurse Practitioner Practices [PDF]

, 2016
Presented to the Faculty of the University of Alaska Anchorage in Partial Fulfillment of the Requirements for the Degree of MASTER OF SCIENCEThe purpose of this project was to determine chronic opioid pain management practices of Alaskan Nurse ...
Klein, Stephanie
core  

Misdiagnosis, Mistreatment, and Harm - When Medical Care Ignores Social Forces. [PDF]

, 2020
The Case Studies in Social Medicine demonstrate that when physicians use only biologic or individual behavioral interventions to treat diseases that stem from or are exacerbated by social factors, we risk harming the patients we seek to ...
Farmer, Paul E, Greene, Jeremy A, Hansen, Helena, Holmes, Seth M, Jenks, Angela, Marmot, Michael G, Morse, Michelle, Stonington, Scott D, Wailoo, Keith A   +8 more
core   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source

Attitudes of Black American Christian church leaders toward Opioid Use Disorder, overdoses, and harm reduction: a qualitative study

Frontiers in Psychiatry
IntroductionBlack American Christian church leaders are trusted community members and can be invaluable leaders and planners, listeners, and counselors for Opioid Use Disorder (OUD) sufferers in the opioid overdose crisis disproportionately affecting the
Akosua B. Dankwah, Richard B. Siegrist, Ira B. Wilson, Ira B. Wilson, Michelle McKenzie, Michelle McKenzie, Josiah D. Rich, Josiah D. Rich   +7 more
doaj   +1 more source

Opioids and cancer survival: are we looking in the wrong place?

BJA Open, 2022
There is a controversial narrative in the anaesthetic literature suggesting that anaesthetic technique (including opioids) may be detrimental to survival after tumour resection. The initial observations were retrospective. Several prospective studies are
Despina Giakomidi, Mark F. Bird, David G. Lambert   +2 more
doaj   +1 more source

Palliative care for people with non-malignant lung disease: summary of current evidence and future direction [PDF]

, 2013
Background: The physical and psychosocial needs of patients with chronic non-malignant lung disease are comparable to those with lung cancer. This article will focus on chronic obstructive pulmonary disease, interstitial lung disease and cystic fibrosis ...
Boland, Jason, Martin, Jonathan, Ross, Joy R, Ross, Joy R., Wells, Athol U, Wells, Athol U.   +5 more
core   +1 more source

Short‐Term Outcomes of Robot‐Assisted Versus Laparoscopic Colectomy for Colon Cancer: A Propensity Score‐Matched Analysis

Annals of Gastroenterological Surgery, EarlyView.
This study compared short‐term outcomes of robot‐assisted versus laparoscopic colectomy for colon cancer using 1:1 propensity score matching. Among 218 matched pairs, robot‐assisted colectomy was associated with reduced blood loss, fewer conversions to open surgery, lower overall complication rates, and shorter hospital stays, despite longer operative ...
Akira Inoue, Yujiro Nishizawa, Yoshinori Kagawa, Masahiro Hashimoto, Shinya Kato, Yoshihiro Morimoto, Taishi Hata, Makoto Fujii, Masaaki Motoori, Kazumasa Fujitani   +9 more
wiley   +1 more source