Results 41 to 50 of about 186,280 (306)

Real-world patterns of opioid therapy initiation in Spain, 2012–2018: A population-based, retrospective cohort study with 957,080 patients and 1,509,488 initiations

Frontiers in Pharmacology, 2022
Introduction: Europe has seen a steady increase in the use of prescription opioids, especially in non-cancer indications. Epidemiological data on the patterns of use of opioids is required to optimize prescription.
Isabel Hurtado, Isabel Hurtado, Celia Robles, Celia Robles, Salvador Peiró, Salvador Peiró, Aníbal García-Sempere, Aníbal García-Sempere, Fran Llopis-Cardona, Fran Llopis-Cardona, Francisco Sánchez-Sáez, Francisco Sánchez-Sáez, Clara Rodríguez-Bernal, Clara Rodríguez-Bernal, Gabriel Sanfélix-Gimeno, Gabriel Sanfélix-Gimeno   +15 more
doaj   +1 more source

Profile of drug users in the residential treatment centers of Tehran, Iran [PDF]

Health Promotion Perspectives, 2019
Background: The current study aimed at determining the pattern of drug dependence and its related factors in mid-term residential treatment centers (MTRCs). Methods: The current cross-sectional study was conducted on all drug dependent people residing in
Hossein Akbari, Mohsen Roshanpajouh, Keramat Nourijelyani, Mohammad-Ali Mansournia, Afarin Rahimi-Movaghar, Kamran Yazdani   +5 more
doaj   +1 more source

Prescribing opioids in general practice [PDF]

, 2017
In this scenario you are working as a practice nurse in a large GP practice. Your local formulary recommends morphine as the first line strong opioid analgesic.
Davies, Janice Anne, Janice Davies
core   +1 more source

EFFICACY OF PAIN MANAGEMENT AT PREHOSPITAL STAGE IN CHILDREN WITH SEVERE THERMAL TRAUMA

Вестник анестезиологии и реаниматологии, 2018
To describe the frequency and type of EMS analgesic administration to burned children; to describe pain after PICU admission used specific score FLACC and Wong-Baker FACES factors associated with the administration of analgesia by EMS.
D. K. Azovskiy, A. U. Lekmanov, L. I. Budkevich, S. F. Pilutik, D. S. Gudilov   +4 more
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Single Fascia Iliaca Compartment Block is Safe and Effective for Emergency Pain Relief in Hip-fracture Patients

Western Journal of Emergency Medicine, 2015
Introduction: Currently, it is common practice in the emergency department (ED) for pain relief in hip-fracture patients to administer pain medication, commonly systemic opioids.
Leonieke Groot, Lea M. Dijksman, Maarten P. Simons, Mariska M.S. Zwartsenburg, Jasper R. Rebel   +4 more
doaj   +1 more source

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli, Karine Lacourse, Hélène Blais, Anne‐Sophie Deshaies‐Rugama, Cynthia Thompson, Alex Desautels, Jacques Montplaisir, Milan Nigam, Christophe Moderie, Boshra Khajehpiri, Catherine Duclos, Jean Marc Lina, Julie Carrier, Nadia Gosselin   +13 more
wiley   +1 more source

Unwanted Clinical Complications Following the Consumption of Death Coffee: A Case Series

Neuropsychopharmacology Reports
“Death Coffee” is an incredibly potent brew with caffeine content three times higher than conventional coffees, making it the strongest coffee in the world.
Amir‐Hassan Bordbari, Mahkameh Soltani, Yousef Ashoori, Fatemeh Moslemi Najarcolaii, Zakaria Zakariaei   +4 more
doaj   +1 more source

Determinants of nurses' intention to administer opioids for pain relief [PDF]

, 2001
A statewide cross-sectional survey was conducted in Australia to identify the determinants of registered nurses' intention to administer opioids to patients with pain.
Anne M. Walsh, McDowell, Jan K., Patsy M. Yates, Najman, J. M., Skerman, H. M., Fentiman, Belinda J., Yates, P. M., Belinda J. Fentiman, Walsh, A. M., Nash, R., Jan K. McDowell, Fentiman, B. J., Dewar, A. M., Yates, Patsy, Helen E. Edwards, Anne Dewar, McDowell, J. K., Walsh, Anne M., Nash, Robyn E., Skerman, Helen M., Helen M. Skerman, Najman, Jackob M., Jake M. Najman, Edwards, Helen E., Edwards, H. E., Dewar, Anne M., Robyn E. Nash   +26 more
core   +1 more source