Results 41 to 50 of about 166,726 (313)

Single Fascia Iliaca Compartment Block is Safe and Effective for Emergency Pain Relief in Hip-fracture Patients

open access: yesWestern Journal of Emergency Medicine, 2015
Introduction: Currently, it is common practice in the emergency department (ED) for pain relief in hip-fracture patients to administer pain medication, commonly systemic opioids.
Leonieke Groot   +4 more
doaj   +1 more source

Concomitant benzodiazepine and opioids decrease sleep apnoea risk in chronic pain patients

open access: yesERJ Open Research, 2020
Background The concurrent use of sedating centrally acting drugs and opioids by chronic pain patients occurs routinely despite concerns of negative impacts on respiration during sleep.
Soodaba Mir   +7 more
doaj   +1 more source

Health Care Use Among Patients Presenting to Emergency Department for Gout Flares in Ontario, Canada: A Population‐Based Health Systems Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective We characterized emergency department (ED) gout visits and identified patient characteristics and health services patterns contributing to ED presentations. Methods We conducted a population‐based study of ED gout visits in Ontario, Canada, between 2014 and 2023.
Timothy S. H. Kwok   +7 more
wiley   +1 more source

Evaluation of Ligand-Based Models on Opioids Receptors Form Street Emerged Hits

open access: yesEmerging Trends in Drugs, Addictions, and Health
The misuse of opioids has become a major public health crisis worldwide. Synthetic opioids, in particular, pose a significant danger due to their potency and potential for addiction.
V. Catalani   +3 more
doaj   +1 more source

Beyond the Syndemic of Opioid Use Disorders and HIV: The Impact of Opioids on Viral Reservoirs

open access: yesViruses, 2023
People with HIV are more likely to have opioid use disorder and to be prescribed opioids for chronic pain than the general population; however, the effects of opioids on the immune system and HIV persistence have not been fully elucidated.
Mattia Trunfio   +7 more
doaj   +1 more source

Clinician and patient factors associated with long‐term glucocorticoid use in people with rheumatoid arthritis on advanced therapies

open access: yesArthritis Care &Research, Accepted Article.
Background Despite guideline recommendations, long‐term glucocorticoid (GC) use is common in rheumatoid arthritis (RA). We conducted a clinician survey nested within a large registry to identify patient and clinician factors associated with GC use. Methods Clinicians contributing patients to the CorEvitas Rheumatoid Arthritis registry were surveyed ...
Michael D. George   +7 more
wiley   +1 more source

Effectiveness and risks associated with long-term use of opioids in chronic pain. [PDF]

open access: yes, 2018
Long-term use of opioids is prevalent in medicine due to the increasing diagnosis of chronic pain. This thesis evaluates how effective their use is in long-term treatment and adverse effects associated with opioid use.általános orvosangolegységes ...
Asante Boateng, Bendelyn
core  

Chiral Microneedle Arrays With Terahertz Chiroptical Activity With Chiral‐Plasmon‐Chiral‐Phonon Resonance

open access: yesAdvanced Materials, EarlyView.
ABSTRACT Microneedle arrays (MNAs) is a rapidly emerging technology with broad biomedical applications in drug delivery and biosensing. With sub‐millimeter dimensions and periodicity, MNAs possess geometries nearly ideal for biomedical devices operating within the terahertz (THz) spectral window.
Sang Hyun Lee   +6 more
wiley   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

open access: yesAdvanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu   +14 more
wiley   +1 more source

Ergotamine/Caffeine Overdose in a Female Suffering From Migraine Headache: A Case Report [PDF]

open access: yesPharmaceutical and Biomedical Research
Background: Ergotamine is a very common antimigraine and is widely used in the management of headaches such as cluster and acute migraines. However, Ergotamine poisoning is an infrequent condition, and there are very few cases reported.
Amir Hasan Farzaneh, Navid Khosravi
doaj  

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