Results 21 to 30 of about 166,726 (313)

Pharmacology of opioids as a drug of abuse [PDF]

, 2020
The object of this thesis is to review the pharmacology of opioids as drugs of abuse. It focuses on the pharmacology of opioids, its antagonist, naloxone, and their use in the current rise in opioid related overdoses.
Eiríksdóttir, Ríkey
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A Nationwide Hospital Claims Database Analysis of Real-World Patterns of Laxative Use for Opioid-Induced Constipation in Japanese Patients with Cancer

Pain and Therapy, 2023
Introduction Opioid-induced constipation (OIC) is one of the most common side effects in patients with cancer treated with opioid analgesics. The actual use of laxatives for OIC in Japan remains unelucidated.
Takahiro Higashibata, Takaomi Kessoku, Yasuhide Morioka, Yuichi Koretaka, Hirokazu Mishima, Hidetoshi Shibahara, Yuriko Masuda, Yasushi Ichikawa, Atsushi Nakajima, Takayuki Hisanaga   +9 more
doaj   +1 more source

Pilot findings on the real-world performance of xylazine test strips for drug residue testing and the importance of secondary testing methods

Drug and Alcohol Dependence Reports
Background: Xylazine is a sedative found increasingly in the illicit fentanyl supply that can cause hypotension, bradycardia, necrosis and death. This pilot examined the real-world performance of BTNX xylazine test strips (XTS) in drug residue samples ...
Erin Thompson, Jessica Tardif, Merci Ujeneza, Adina Badea, Traci C. Green, Haley McKee, Michelle McKenzie, Ju Nyeong Park   +7 more
doaj   +1 more source

Factors related to the use of opioids as early treatment in patients with knee osteoarthritis

Arthritis Research & Therapy, 2019
Objective To examine factors related to the use of opioids as an early treatment option for knee OA patients Methods Using the Korean nationwide claim database, we selected knee OA patients between 2013 and 2015. Among them, patients without any claim of
Soo-Kyung Cho, Sun-Young Jung, Seongmi Choi, Seul Gi Im, Hyoungyoung Kim, Woo Seok Choi, Eun Jin Jang, Yoon-Kyoung Sung   +7 more
doaj   +1 more source

Quantifying unused opioids following emergency and ambulatory care: A systematic review and meta‐analysis

Journal of the American College of Emergency Physicians Open, 2022
Objective To quantify unused opioids among adult and pediatric patients discharged from the emergency department (ED) or ambulatory care settings with a prescription for acute pain.
Michele P. Dyson, Kathryn Dong, William Sevcik, Samir Z. Graham, Sabrina Saba, Lisa Hartling, Samina Ali   +6 more
doaj   +1 more source

Knowledge Mapping of Opioids and Immunomodulation: A Bibliometric Analysis (2000–2022) [PDF]

, 2023
Subinuer Kurexi,1 Ke Wang,2 Tongyu Chen1 1Department of Cardiothoracic Surgery, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China ...
Kurexi S, Wang K, Chen T
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Opioids: risk of dependence and addiction. [PDF]

, 2020
New UK recommendations following a review of the risks of dependence and addiction associated with prolonged use of opioid medicines (opioids) for non-cancer pain.

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Effects of sedatives and opioids on trigger and cycling asynchronies throughout mechanical ventilation: an observational study in a large dataset from critically ill patients

Critical Care, 2019
Background In critically ill patients, poor patient-ventilator interaction may worsen outcomes. Although sedatives are often administered to improve comfort and facilitate ventilation, they can be deleterious.
Candelaria de Haro, Rudys Magrans, Josefina López-Aguilar, Jaume Montanyà, Enrico Lena, Carles Subirà, Sol Fernandez-Gonzalo, Gemma Gomà, Rafael Fernández, Guillermo M. Albaiceta, Yoanna Skrobik, Umberto Lucangelo, Gastón Murias, Ana Ochagavia, Robert M. Kacmarek, Montserrat Rue, Lluís Blanch, for the Asynchronies in the Intensive Care Unit (ASYNICU) Group   +17 more
doaj   +1 more source

Real-world patterns of opioid therapy initiation in Spain, 2012–2018: A population-based, retrospective cohort study with 957,080 patients and 1,509,488 initiations

Frontiers in Pharmacology, 2022
Introduction: Europe has seen a steady increase in the use of prescription opioids, especially in non-cancer indications. Epidemiological data on the patterns of use of opioids is required to optimize prescription.
Isabel Hurtado, Isabel Hurtado, Celia Robles, Celia Robles, Salvador Peiró, Salvador Peiró, Aníbal García-Sempere, Aníbal García-Sempere, Fran Llopis-Cardona, Fran Llopis-Cardona, Francisco Sánchez-Sáez, Francisco Sánchez-Sáez, Clara Rodríguez-Bernal, Clara Rodríguez-Bernal, Gabriel Sanfélix-Gimeno, Gabriel Sanfélix-Gimeno   +15 more
doaj   +1 more source

Profile of drug users in the residential treatment centers of Tehran, Iran [PDF]

Health Promotion Perspectives, 2019
Background: The current study aimed at determining the pattern of drug dependence and its related factors in mid-term residential treatment centers (MTRCs). Methods: The current cross-sectional study was conducted on all drug dependent people residing in
Hossein Akbari, Mohsen Roshanpajouh, Keramat Nourijelyani, Mohammad-Ali Mansournia, Afarin Rahimi-Movaghar, Kamran Yazdani   +5 more
doaj   +1 more source