Results 31 to 40 of about 166,726 (313)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

EFFICACY OF PAIN MANAGEMENT AT PREHOSPITAL STAGE IN CHILDREN WITH SEVERE THERMAL TRAUMA

Вестник анестезиологии и реаниматологии, 2018
To describe the frequency and type of EMS analgesic administration to burned children; to describe pain after PICU admission used specific score FLACC and Wong-Baker FACES factors associated with the administration of analgesia by EMS.
D. K. Azovskiy, A. U. Lekmanov, L. I. Budkevich, S. F. Pilutik, D. S. Gudilov   +4 more
doaj   +1 more source

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source

Unwanted Clinical Complications Following the Consumption of Death Coffee: A Case Series

Neuropsychopharmacology Reports
“Death Coffee” is an incredibly potent brew with caffeine content three times higher than conventional coffees, making it the strongest coffee in the world.
Amir‐Hassan Bordbari, Mahkameh Soltani, Yousef Ashoori, Fatemeh Moslemi Najarcolaii, Zakaria Zakariaei   +4 more
doaj   +1 more source

The Nature of Opioids Used as Pain Management in A Public Hospital in Bali

Jurnal Ilmiah Medicamento
Opioids are the mainstay of pain management, particularly in chronic pain-related and nonrelated cancer. Studies have shown that the number of opioids used globally varies. It was used excessively in some parts, while in others, it was underused.
Desak Ketut Ernawati, Agata Widatama
doaj   +1 more source

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

Arthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer, Rui Xiao, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +4 more
wiley   +1 more source

Pharmacology of Opioids [PDF]

, 2014
Opioids have been used for thousands of years for the treatment of pain. It was revealed that the drug bound to very special areas of the brain which were subsequently called morphine receptors. Until now, a wide range of the these receptors and subtypes
Ahmadi, Arash
core  

Neighborhood Socioeconomic Status and Short‐Term Functional Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective Individuals with systemic lupus erythematosus (SLE) can accumulate functional status (FS) impairment. We evaluated the association between neighborhood socioeconomic disadvantage, as measured by the Area Deprivation Index (ADI), and FS in a national SLE sample.
Baljeet Rai, Jessica Fitzpatrick, Jing Li, Eric Roberts, Patricia Katz, Laura Plantinga, Gabriela Schmajuk, Jinoos Yazdany   +7 more
wiley   +1 more source

Use of immediate-release opioids as supplemental analgesia during management of moderate-to-severe chronic pain with buprenorphine transdermal system [PDF]

, 2017
Sanford Silverman,1,2 Robert B Raffa,3,4 Marc J Cataldo,5 Monica Kwarcinski,5 Steven R Ripa5 1Comprehensive Pain Medicine, Pompano Beach, 2Department of Integrated Medical Sciences, Charles E Schmidt College of Medicine, Florida Atlantic University, Boca
Kwarcinski, Monica, Raffa RB, Robert B Raffa, Marc Cataldo, Ripa, Steven R., Silverman, Sanford, Steven R. Ripa, Sanford Silverman, Monica Kwarcinski, Kwarcinski M, Ripa SR, Cataldo, Marc, Silverman S, Cataldo MJ, Raffa, Robert B   +14 more
core   +2 more sources

A Novel Class of “Super‐Strained” Spiro Heterocycles: Gateway to 1‐Azaspiro[3.3]heptane Derivatives, and Biological Validation

Angewandte Chemie, EarlyView.
A new class of “super‐strained” spiro heterocycles—spirocyclic 1‐azabicyclo[1.1.0]butanes—was synthesized via insertion of cyclobutane‐, oxetane‐, and azetidine‐containing sulfonium reagents into substituted azirines. The stability of this new class of compounds was studied.
Philipp Natho, Annarita Vicenti, Marco Colella, Francesco Pasca, Giuseppe Romanazzi, Mauro Niso, Carmen Abate, Ernesto Mesto, Emanuela Schingaro, Renzo Luisi   +9 more
wiley   +2 more sources