Misclassification of Opisthorchis viverrini and Minute Intestinal Fluke Eggs by Routine Laboratory Staff Using Images from the Kato-Katz Method. [PDF]
Wisetmoraa A +5 more
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A study protocol for a multi-country cluster randomized controlled trial of the impact of a multi-component One Health strategy to eliminate Opisthorchis viverrini and soil transmitted helminths in the Lower Mekong Basin. [PDF]
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Epidemiology of Opisthorchis viverrini
Acta Tropica, 2003Opisthorchis viverrini is a food borne trematode, important because of the sheer numbers of people infected and its serious morbidities such as hepatobiliary diseases and cholangiocarcinoma (CHCA). Although infections are identified throughout Southeast Asia, the epi-center is northeast Thailand, where high prevalence coexists with a high incidence of ...
Sithithaworn, P., Haswell-Elkins, M.
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Opisthorchis viverrini: The tegumental cytoskeleton
International Journal for Parasitology, 1995The tegumental cytoskeleton of Opisthorchis viverrini was observed using both conventional transmission electron microscopy and Triton X-100 extraction. The cytoskeletal elements of the newly excysted juveniles, first-week and adult stages are composed of 2 components: firstly, the network of knobbed fibres designated as microtrabeculae which form the ...
P, Sobhon, W, Apinhasmit
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Animal models for Opisthorchis viverrini infection
Parasitology Research, 2008We investigated the utility of various animal models for the study of opisthorchiasis in humans and its common sequel of cholangiocarcinoma (CCA). Rats, mice, gerbils, and hamsters were infected with Opisthorchis viverrini metacercariae. Worms from the infected animal hosts were recovered from livers and counts made of eggs per gram of feces.
Thidarut, Boonmars +2 more
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Monoclonal antibodies against Opisthorchis viverrini antigens
Parasite Immunology, 1990Summary Monoclonal antibodies (MoAb) were produced against somatic antigens of adult human liver fluke Opisthorchis viverrini. Earlier studies attached diagnostic potential to an 89–90 kD antigen present in both somatic extracts and in vitro culture supernatants as well as to the abundant 16–17 kD tegumental protein doublet.
P B, Billings, N, Utsakhit, S, Sirisinha
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Specific monoclonal antibodies to Opisthorchis viverrini
International Journal for Parasitology, 1991A Balb/c mouse was immunized with a crude soluble antigen of Opisthorchis viverrini adult worms (OVAA) over a period of 7 months. Spleen cells from the immune mouse were fused with Sp2/0 myeloma cells. Among the 264 tissue culture wells containing the fused cells, cells of 96 wells (36%) produced antibodies to the immunizing agent.
W, Chaicumpa +8 more
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Bi-functionality of Opisthorchis viverrini aquaporins
Biochimie, 2015Aquaporins (AQP) are essential mediators of water regulation in all living organisms and members of the major intrinsic protein (MIP) superfamily of integral membrane proteins. They are potential vehicles or targets for chemotherapy, e.g. in Trypanosoma brucei melarsoprol and pentamidine uptake is facilitated by TbAQP-2.
Amornrat, Geadkaew +5 more
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Genetics of Opisthorchis viverrini-related cholangiocarcinoma
Current Opinion in Gastroenterology, 2015We review the genetic, epigenetic and transcriptional landscape of liver fluke (Opisthorchis viverrini, Ov)-related cholangiocarcinoma (CCA). Its distinct alterations, as compared with non-Ov-related CCA may help shed light on its underlying molecular mechanisms.Recent whole-exome and targeted sequencing not only confirmed frequent mutations in known ...
Apinya, Jusakul +2 more
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Epidemiology of Opisthorchis viverrini Infection
2018Opisthorchiasis in the Lower Mekong Subregion is a parasitic disease caused by the liver fluke Opisthorchis viverrini. This parasite has a well-documented distribution in Thailand, Lao PDR, Cambodia, Myanmar and Southern Vietnam. In this chapter, we describe the current knowledge of the epidemiology of O.
Suwannatrai, Apiporn +2 more
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