Results 41 to 50 of about 8,141 (222)

CP-673451, a Selective Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitor, Induces Apoptosis in Opisthorchis viverrini-Associated Cholangiocarcinoma via Nrf2 Suppression and Enhanced ROS

Pharmaceuticals, 2023
Platelet-derived growth factors (PDGFs) and PDGF receptors (PDGFRs) play essential roles in promoting cholangiocarcinoma (CCA) cell survival by mediating paracrine crosstalk between tumor and cancer-associated fibroblasts (CAFs), indicating the potential
Jinchutha Duangdara, Boonyakorn Boonsri, Apinya Sayinta, Kittiya Supradit, Pakpoom Thintharua, S. Kumkate, C. Suriyonplengsaeng, N. Larbcharoensub, S. Mingphruedhi, N. Rungsakulkij, P. Muangkaew, P. Tangtawee, W. Vassanasiri, W. Suragul, T. Janvilisri, R. Tohtong, David O Bates, K. Wongprasert   +17 more
semanticscholar   +1 more source

In silico prediction of secretory proteins of Opisthorchis viverrini, Clonorchis sinensis and Fasciola hepatica that target the host cell nucleus

Heliyon, 2021
Liver flukes Fasciola hepatica, Opisthorchis viverrini and Clonorchis sinensis are causing agents of liver and hepatobiliary diseases. A remarkable difference between such worms is the fact that O. viverrini and C.
Claudia Machicado, Maria Pia Soto, Luis Felipe La Chira, Joel Torres, Carlos Mendoza, Luis A. Marcos   +5 more
doaj   +1 more source

Production and Immunological Characterization of scFv Specific to Epitope of Opisthorchis viverrini Rhophilin-Associated Tail Protein 1-like (OvROPN1L)

Tropical Medicine and Infectious Disease, 2023
(1) Background: Opisthorchis viverrini is a significant health problem in the Mekong subregion of Southeast Asia, causing aggressive cholangiocarcinoma. Current diagnostic procedures do not cover early diagnosis and low infection.
Amornrat Geadkaew-Krenc, Dawid Krenc, Jeeraphong Thanongsaksrikul, R. Grams, Wansika Phadungsil, Kittirat Glab-ampai, Pathanin Chantree, Pongsakorn Martviset   +7 more
semanticscholar   +1 more source

Rapid label-free analysis of Opisthorchis viverrini eggs in fecal specimens using confocal Raman spectroscopy.

PLoS ONE, 2019
Opisthorchis viverrini, a human liver fluke, is highly prevalent in Southeast Asia. Definitive diagnosis of infection is usually achieved parasitologically through the discovery of fluke eggs in feces. However, the eggs of O.
Oranat Chuchuen, Thani Thammaratana, Oranuch Sanpool, Rutchanee Rodpai, Wanchai Maleewong, Pewpan M Intapan   +5 more
doaj   +1 more source

Prevalence of Opisthorchis viverrini and its Associated Risk Factors in the Phon Sawan District of Nakhon Phanom Province, Thailand

Iranian Journal of Parasitology, 2021
Background: Opisthorchis viverrini is one of the endemic helminths in Thailand. Nonetheless, O. viverrini still exist and raise concerns regarding public health. This study aimed to evaluate the current prevalence of O.
Chaiwat Srithai, Sriwipa Chuangchaiya, Siriluk Jaichuang, Zulkarnain Md Idris   +3 more
doaj   +1 more source

Opisthorchis viverrini: The carcinogenic human liver fluke [PDF]

World Journal of Gastroenterology, 2008
Opisthorchiasis caused by Opisthorchis viverrini remains a major public health problem in many parts of Southeast Asia, including Thailand, Lao PDR, Vietnam and Cambodia. The infection is associated with a number of hepatobiliary diseases, including cholangitis, obstructive jaundice, hepatomegaly, cholecystitis and cholelithiasis.
Natthawut, Kaewpitoon, Soraya-J, Kaewpitoon, Prasit, Pengsaa, Banchob, Sripa   +3 more
openaire   +2 more sources

Unraveling the relationship among inflammatory responses, oxidative damage, and host susceptibility to Opisthorchis viverrini infection: A comparative analysis in animal models

Veterinary World, 2023
Background and Aim: Opisthorchis viverrini infection-induced inflammation contributes to cholangiocarcinoma (CCA) development in humans and animals. Inflammation generates free radicals, such as reactive oxygen species and reactive nitrogen species (RNS),
S. Tangkawattana, Watcharapol Suyapoh, Nathamon Taiki, Paramin Tookampee, Ravisara Chitchak, Theerayut Thongrin, P. Tangkawattana   +6 more
semanticscholar   +1 more source

Discovery of Serotransferrin Glycoforms: Novel Markers for Diagnosis of Liver Periductal Fibrosis and Prediction of Cholangiocarcinoma. [PDF]

, 2019
Cholangiocarcinoma (CCA) caused by chronic liver fluke infection is a major public health problem in Northeast Thailand. Identification of CCA risk groups is urgently needed for the control of CCA in this region.
Barboza, Mariana, Chamadol, Nittaya, Jamnongkan, Wassana, Khuntikeo, Narong, Lebrilla, Carlito B, Loilome, Watcharin, Pairojkul, Chawalit, Sithithaworn, Paiboon, Techasen, Anchalee, Thanan, Raynoo, Yongvanit, Puangrat   +10 more
core   +2 more sources

Distinct antibody response in susceptible and non-susceptible hosts of the carcinogenic liver fluke Opisthorchis viverrini infection

Parasitology, 2023
Abstract Opisthorchis viverrini is a carcinogenic parasite that can cause bile duct cancer called cholangiocarcinoma. A study of the immune response of this parasite in susceptible and non-susceptible hosts may provide a clue to develop vaccines and ...
Krongkarn Watakulsin, Arpa Surapaitoon, Lorina Handayani Ulag, Sunheng Kaing, Watcharapol Suyapoh, P. Saichua, Kanin Salao, Sirikachorn Tangkawatana, Sutas Suttiprapa   +8 more
semanticscholar   +1 more source

The ultrastructure of helminth. VI. The body wall of Opisthorchis viverrini (Poirier, 1886) [PDF]

, 1971
Electron microscopy of the body wall of Opisthorchis viverrini shows the integument which is connected to the epidermal cell with fine protoplasmic tubules, to form a syncytium, as in Clonorchis sinensis and other trematodes.
Inatomi, Seiiti, Itano, Kazuo, Sakumoto, Daigoro, Suguri, Setsuo, Tongu, Yasumasa   +4 more
core   +1 more source