Results 61 to 70 of about 2,790 (126)

Genomic Profiling of Biliary Tract Cancers: Comprehensive Assessment of Anatomic and Geographic Heterogeneity, Co‐Alterations and Outcomes

Journal of Surgical Oncology, Volume 131, Issue 7, Page 1352-1361, June 2025.
ABSTRACT Background Biliary tract cancers (BTCs) represent distinct biological and genomic entities. Anatomic and geographic heterogeneity in genomic profiling of BTC subtypes, genomic co‐alterations, and their impact on long‐term outcomes are not well defined.
Diamantis I. Tsilimigras, Hunter Stecko, Dimitrios Moris, Timothy M. Pawlik   +3 more
wiley   +1 more source

Integrating Aggregate Materials and Machine Learning Algorithms: Advancing Detection of Pathogen‐Derived Extracellular Vesicles

Aggregate, Volume 6, Issue 5, May 2025.
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai, Yun Su, Cong Hu, Zehong Peng, Wei Xue, Liang Dong, Tony Y. Hu   +6 more
wiley   +1 more source

Detection of Opisthorchis viverrini Infection among the ASEAN Population in Thailand Using a Verbal Screening Test and Fecal Concentrator Kit

Iranian Journal of Parasitology, 2018
Background: Opisthorchis viverrini is a serious health problem in Southeast Asia. The infection is associated with cholangiocarcinoma. Therefore, this study was aimed to detect O. viverrini infections among the ASEAN population in Thailand.
Natthawut KAEWPITOON, Soraya KAEWPITOON, Thirayu MEERERKSOM, Siwawich CHAN-ARAN, Wararat SANGWALEE, Jun NORKAEW, Jirayu CHUATANAM, Jirawoot KUJAPAN, Natnapa PADCHASUWAN, Taweesak TONGTAWEE, Likit MATRAKOOL, Ryan LOYD, Parichart WAKKHUWATTHAPONG   +12 more
doaj  

Structural analysis of an Asterias rubens peptide indicates the presence of a disulfide‐directed β‐hairpin fold

FEBS Open Bio, Volume 15, Issue 3, Page 415-426, March 2025.
Sea stars have remarkable regenerative capabilities. A peptide, KASH2, identified in the biofluid of the common sea star Asterias rubens appears to be involved with the wound‐healing response in the organism. Here, we show the 3D structure of KASH2 adopts a disulfide‐directed β‐hairpin fold, a fold only previously found in arachnids, and does not show ...
Rozita Takjoo, David T. Wilson, Justine Le Quilliec, Casey A. Schmidt, Guangzu Zhao, Michael J. Liddell, Naeem Y. Shaikh, Kartik Sunagar, Alex Loukas, Michael J. Smout, Norelle L. Daly   +10 more
wiley   +1 more source

A Spatially Explicit Model of the Dynamics of Opisthorchis viverrini Spread

Ecohydrology, Volume 18, Issue 2, March 2025.
ABSTRACT Opisthorchis viverrini is a water‐based disease‐causing parasite whose public health implications are relevant in Southeast Asia. Untreated or chronic infections often lead to severe hepatobiliary morbidity including cholangiocarcinoma, a lethal bile duct cancer. The liver fluke O.
Cristiano Trevisin, Lars Kamber, Lorenzo Mari, Nakul Chitnis, Javier Perez‐Saez, Somphou Sayasone, Peter Odermatt, Marino Gatto, Andrea Rinaldo   +8 more
wiley   +1 more source

The role of liver fluke invasion in the pathogenesis of cholangiocarcinoma

Clinical & Experimental Hepatology
Infections with the liver flukes Clonorchis sinensis and Opisthorchis viverrini are currently endemic in Southeast and East Asia. Their limited ecological and geographical distribution is caused by environmental factors and culinary habits of the human ...
Martyna Bykowska-Tumasz, Katarzyna Sikorska   +1 more
doaj   +1 more source

How Do Trematodes Induce Cancer? A Possible Evolutionary Adaptation of an Oncogenic Agent Transmitted by Flukes

Evolutionary Applications, Volume 18, Issue 1, January 2025.
ABSTRACT There is strong epidemiological evidence that development of various cancer types is linked to infection with flukes (Platyhelminthes: Trematoda) in Africa, Asia and the Middle East. The exact nature of the mechanism by which cancer is induced by these parasites is unknown.
Péter Apari, Gábor Földvári
wiley   +1 more source

Influence of geographic, knowledge and behavioral factors on Opisthorchis viverrini infection in the Northeast of Thailand

Asian Pacific Journal of Tropical Medicine, 2019
Objective: To determine the influence of geographic, knowledge and behavioral factors on Opisthorchis (O.) viverrini infection in the Northeast of Thailand.
Kittipong Sornlorm, Wongsa Loahasiriwong, Paiboon Sithithaworn, Wilaiphorn Thinkhamrop   +3 more
doaj   +1 more source

Predictors of hookworm and Opisthorchis viverrini infection among adolescents in urban Laos: a cross-sectional study

Research and Reports in Tropical Medicine, 2019
Itsuko Yoshida,1 Osamu Horie,2 Kongsap Akkhavong31Department of Nursing Science, Yasuda Women’s University, Hiroshima, Japan; 2Department of Clinical Laboratory Science, Tenri Health Care University, Tenri, Nara, Japan; 3Lao Tropical and Public ...
Yoshida I, Horie O, Akkhavong K
doaj  

Spatial patterns and risk mapping of opisthorchiasis and soil-transmitted helminth infections in Thailand using Bayesian geostatistical models

Scientific Reports
Opisthorchis viverrini and soil-transmitted helminths (STH) remain major public health challenges in Thailand due to their widespread distribution. This study aimed to map and predict the prevalence of O.
Khanittha Pratumchart, Apiporn T. Suwannatrai, Oranard Wattanawong, Kavin Thinkhamrop, Kulwadee Suwannatrai, Ampas Wisetmora, Suphansa Wichairattanagull, Nichaphat Kukitirat, Thitima Wongsaroj, Pariwate Varnakovida, Thidarut Boonmars, Angela Cadavid Restrepo, Mary Lorraine Sagarang Mationg, Archie C. A. Clements, Kinley Wangdi, Banchob Sripa, Darren J. Gray   +16 more
doaj   +1 more source