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Establishment of Male and Female Eucommia Fingerprints by UPLC Combined with OPLS‐DA Model and Its Application

Chemistry & Biodiversity, 2023
AbstractEucommia ulmoides Oliver is a dioecious plant, which plays an important role in traditional Chinese medicine. However, there has not yet been any research on male and female E. ulmoides. The UPLC fingerprints and OPLS‐DA approach were able to quickly and easily identify and quantify E.
Jinling You   +11 more
openaire   +2 more sources

Analyze Efficacy of Traditional Chinese Medicine Based on OSC-OPLS-DA

Applied Mechanics and Materials, 2012
Metabolomics is a good means for analyze Traditional Chinese Medicine efficacy. The paper purpose a methods to deal with the Metabolomics data, and analyze the efficacy of Traditional Chinese Medicine based on OSC-OPLS/O2PLS-DA. The method was proved to be feasible and effective after tested the data which hot natures treat the cold syndrome.
Bin Nie   +6 more
openaire   +1 more source

Metabolic implications of amino acid metabolites in chronic kidney disease progression: a metabolomics analysis using OPLS-DA and MBRole2.0 database

International Urology and Nephrology, 2023
As chronic kidney disease (CKD) progresses, metabolites undergo diverse transformations. Nevertheless, the impact of these metabolic changes on the etiology, progression, and prognosis of CKD remains uncertain. Our objective is to conduct a metabolomics analysis to scrutinize metabolites and identify significant metabolic pathways implicated in CKD ...
Jianhao Kang   +9 more
openaire   +2 more sources

Discovery of markers for discriminating the age of cultivated ginseng by using UHPLC-QTOF/MS coupled with OPLS-DA

Phytomedicine, 2018
Ginseng (Ginseng Radix et Rhizoma, Panax ginseng C.A. Meyer) is gaining more publicity in modern society due to its health benefit and huge value in market. In the practice of grading and pricing of ginseng, the age is one of the major factor influencing the price and grade of ginseng.
Bao-Ming Huang   +8 more
openaire   +2 more sources

OPLS-DA as a Suitable Method for Selecting a Set of Gene Transcripts Discriminating RAS- and PTPN11-Mutated Cells in Acute Lymphoblastic Leukaemia

Combinatorial Chemistry & High Throughput Screening, 2011
OPLS discriminant analysis (OPLS-DA) was successfully applied for the selection of a limited number of gene transcripts necessary to discriminate PTPN11 and RAS mutated cells in acute lymphoblastic leukaemia (ALL) patients. The original set of 273 variables with VIP (1) values higher than 2.0 in the OPLS-DA model could be further reduced to 200 by ...
MUSUMARRA, Giuseppe   +2 more
openaire   +2 more sources

Potential geo-discriminative tools to trace the origins of the dried slices of shiitake (Lentinula edodes) using stable isotope ratios and OPLS-DA

Food Chemistry, 2019
The Lentinus edodes species, known as shiitake, has a history of extensive use in many cuisines in several East Asian countries owing to its unique and pleasant flavor and texture. As international food trade increases, reliable discrimination of geographical origin is becoming increasingly crucial in Korea to identify cheaper imported Chinese shiitake.
Ill-Min Chung   +10 more
openaire   +2 more sources

Using OPLS-DA to find new hypotheses in vast amounts of gene expression data — Studying the progression of cardiac hypertrophy in the heart of aorta ligated rat

Gene, 2013
One of the great problems facing science today lies in data mining of the vast amount of data. In this study we explore a new way of using orthogonal partial least squares-discrimination analysis (OPLS-DA) to analyze multidimensional data. Myocardial tissues from aorta ligated and control rats (sacrificed at the acute, the adaptive and the stable ...
Nina, Gennebäck   +4 more
openaire   +2 more sources

Chemical characterisation of weathered polyethylene microplastics in marine coastal waters using OPLS-DA technique and ATR FT-IR spectra

Marine Pollution Bulletin
: Predicting the fate of microplastics (MPs) in the environment and assessing their potential environmental hazard is crucial in defining effective mitigation strategies. This paper presents a novel approach for a comprehensive understanding of stressing factors controlling the distribution of MPs, their degradation and physicochemical transformation ...
Mali, Matilda   +6 more
openaire   +1 more source

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