Results 181 to 190 of about 38,044 (266)

PYGL as a Novel Biomarker for Disease Progression and Prognosis in HEV-ALF Patients. [PDF]

J Med Virol
Feng S, Pan M, Wang L, Ji C, Xiang Z, Wu J, Gu M.   +6 more
europepmc   +1 more source

Zeb2 Controls Retinal Physiological and Pathological Angiogenesis by Regulating Astrocyte Proliferation and Differentiation

Cell Proliferation, EarlyView.
During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu, Yanan Guo, Kangjian Xiang, Shuyi Wang, Dongchang Xiao, Mengqing Xiang   +5 more
wiley   +1 more source

Melatonin seed priming reconfigures the metabolomic profile and functional attributes of brown mustard (Brassica juncea L.) sprouts. [PDF]

Sci Rep
Ghallab DS, Okda TM.
europepmc   +1 more source

Immune Repertoire Profiling Reveals Distinct Adaptive Immune Signatures of Dampness ZHENG Across Psoriasis, Rheumatoid Arthritis and Ulcerative Colitis

Cell Proliferation, EarlyView.
Schematic diagram for the experimental design for adaptome immune repertoire analysing Dampness ZHENG across Psoriasis, Rheumatoid Arthritis and Ulcerative Colitis. ABSTRACT Autoimmune diseases, including psoriasis (Ps), rheumatoid arthritis (RA) and ulcerative colitis (UC), pose significant health burdens worldwide.
Lipeng Tang, Maojie Wang, Yuhong Yan, Shumin Qin, Youbang Liang, Danni Yao, Liyan Mei, Hao Deng, Shuyan Ye, Xiumin Chen, Kaixin Gao, Xirun Zheng, Taohua Liu, Xinmin Qiu, Song Li, Xinjie Yu, Wenjing Pan, Shaogang Huang, Zhe Wang, Runyue Huang, Guangjuan Zheng, Chuanjian Lu   +21 more
wiley   +1 more source

Analysis of Plasma Biomarkers and Potential Pathogenesis in Children with <i>Mycoplasma pneumoniae</i> Pneumonia Based on Metabolomic Technology. [PDF]

Infect Drug Resist
Xu Q, Shen L, Hong L, Li X, Lu M, Ran S.
europepmc   +1 more source

Ammonia Accumulation Drives Intervertebral Disc Degeneration by Triggering Ammonia‐Induced Cell Death Through Lysosome–Mitochondria Crosstalk

Cell Proliferation, EarlyView.
Mechanical strain disrupts the lysosome‐mitochondria axis via GLS1‐mediated ammonia toxicity, causing NP cell death and ECM breakdown in IVDD. CB839‐mediated GLS1 inhibition effectively rescues cellular homeostasis and alleviates disc degeneration.
Yang Zhang, Yucheng Gao, Shuhang Dong, Shuanggong Liu, Lei Liu, Ziyi Song, Jie Xu, Yijun Rong, Guangxu Song, Yingze Zhang, Dongjin Wu, Zengxin Gao   +11 more
wiley   +1 more source

Concurrent training is associated with enhanced post-exercise ceramide clearance and fat oxidation capacity in individuals with type 2 diabetes following lifestyle intervention. [PDF]

Diabetologia
Flockhart M, Svensson M, Ehtesham E, Ryberg M, Stomby A, Åkerfeldt T, Otten J, Olsson T, Chorell E.   +8 more
europepmc   +1 more source

Multimodal Exploratory Analysis of Persistent Diabetic Macular Edema: Integrating Aqueous Humour Metabolomics, Clinical and OCT Features

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Purpose This exploratory study integrates aqueous humour metabolomic data with clinical and imaging features to examine candidate biomarkers and characterize multimodal patterns associated with persistent diabetic macular edema (pDME). Methods In this prospective cohort study, DME patients were treated with monthly anti‐VEGF injections over 3 ...
Yunhan Tao, Huimin Yu, Yunxi Ma, Mingzhu Yuan, Guochong Chen, Jun Liu, Xi Chen, Xufang Sun   +7 more
wiley   +1 more source

Serum 1H NMR-Based Untargeted Metabolomics for Noninvasive Early Detection of Breast Cancer. [PDF]

J Proteome Res
Ali A, Tengku Din TADAA, Maulidiani M, Arafat HM, Abdul Rahman WFW, Mazuwin Yahya M, Kadiman S, Ramli RAB, Wan Azman WN.   +8 more
europepmc   +1 more source

Dragonfly taxonomic and functional responses to urbanized streams in southeastern Europe, with management recommendations

Insect Conservation and Diversity, EarlyView.
Urbanization drives turnover in dragonfly species composition, traits, and habitat conservation value. Natural stream sections have a higher conservation value (higher DBI) due to presence of specialists. Properly managed urban streams can support diverse dragonfly assemblages.
Marina Vilenica, Andreja Brigić, Lea Ružanović, Renata Matoničkin Kepčija, Greet De Knijf, Michael J. Samways   +5 more
wiley   +1 more source