Results 21 to 30 of about 140,857 (270)

Global emergence of a multi-drug resistant fungal pathogen, Candida auris

Southern African Journal of Infectious Diseases, 2016
No abstract available.
Erika Britz, Nelesh P. Govender
doaj   +1 more source

Antifungal Compounds from the Leaves of Rhynchosia minima

Chemistry &Biodiversity, Volume 19, Issue 12, December 2022., 2022
Abstract Rhynchosia minima, commonly known as jumby bean, is used as a remedy for respiratory ailments in various parts of the world. It is also used by South African traditional healers to treat heart or chest pain. This study aimed to investigate the bioactive constituents of the leaf extracts of R.
Adetola H. Adewole, Ibukun M. Famuyide, Lyndy J. McGaw, Mamoalosi A. Selepe, Natasha October   +4 more
wiley   +1 more source

The effect of multiple blood-feeding on the longevity and insecticide resistant phenotype in the major malaria vector Anopheles arabiensis (Diptera: Culicidae)

Parasites & Vectors, 2014
Background Anopheles arabiensis is a major malaria vector in Africa. Adult females are likely to imbibe multiple blood meals during their lifetime. This results in regular exposure to potential toxins and blood-meal induced oxidative stress.
Shüné V Oliver, Basil D Brooke
doaj   +1 more source

Gastrointestinal microbiota composition predicts peripheral inflammatory state during treatment of human tuberculosis

Nature Communications, 2021
Antibiotic therapy can lead to pathogen clearance, but also to alterations in the gut microbiota and systemic immune responses. Here, the authors analyze data from patients with tuberculosis and healthy subjects to show that pathogen clearance and gut ...
Matthew F. Wipperman, Shakti K. Bhattarai, Charles Kyriakos Vorkas, Venkata Suhas Maringati, Ying Taur, Laurent Mathurin, Katherine McAulay, Stalz Charles Vilbrun, Daphie Francois, James Bean, Kathleen F. Walsh, Carl Nathan, Daniel W. Fitzgerald, Michael S. Glickman, Vanni Bucci   +14 more
doaj   +1 more source

Disseminated fatal Talaromyces (Penicillium) marneffei infection in a returning HIV-infected traveller

Southern African Journal of HIV Medicine, 2014
We report a case of disseminated fatal Talaromyces (Penicillium) marneffei infection in an HIV-infected, antiretroviral treatment-experienced South African woman who had travelled to mainland China.
N. P. Govender, R. E. Magobo, M. du Plooy, C. Corcoran, T. G. Zulu   +4 more
doaj   +1 more source

Profile of Opportunistic Infections among HIV Patients Prior to Start of ART in a Tertiary Care Hospital in Rajasthan

RUHS Journal of Health Sciences, 2023
Introduction: HIV infection is a global pandemic causing immunodeficiency resulting in various opportunistic infections among patients suffering from HIV infection.
Sirohi , Akhil Gupta , Shalini Gupta
doaj   +1 more source

Two echinocandin-resistant Candida glabrata FKS mutants from South Africa

Medical Mycology Case Reports, 2016
Echinocandins are recommended as first-line agents to treat invasive infections caused by Candida glabrata since this organism is inherently less susceptible to azoles. However, resistance to echinocandins has been described in C.
Serisha D. Naicker, Rindidzani E. Magobo, Thokozile G. Zulu, Tsidiso G. Maphanga, Nkosinathi Luthuli, Warren Lowman, Nelesh P. Govender   +6 more
doaj   +1 more source

Sialic Acid 4‐N‐Piperazine and Piperidine Derivatives Bind with High Affinity to the P. mirabilis Sialic Acid Sodium Solute Symporter

ChemMedChem, Volume 17, Issue 23, December 5, 2022., 2022
A new target: Bacterial sialic acid uptake inhibition is a promising strategy for the development of antibacterial drugs. In this study, we present the design, synthesis and evaluation of sialic acid 4‐piperidine and piperazine derivatives a novel compound class, which bind the SiaT from Proteus mirabilis and target a different portion of the binding ...
Tiago Bozzola, Richard E. Johnsson, Ulf J. Nilsson, Ulf Ellervik   +3 more
wiley   +1 more source

Acinetobacter baumannii Deactivation by Means of DBD-Based Helium Plasma Jet [PDF]

Plasma 2 (2019) 77-90, 2019
Acinetobacter baumannii is a typically short, almost round, rod-shaped (coccobacillus) Gram-negative bacterium. It can be an opportunistic pathogen in humans, affecting people with compromised immune systems, and it is becoming increasingly important as a hospital-associated (nosocomial) infection.
arxiv   +1 more source

Retention in Care among Patients with Early HIV Disease in Haiti

Journal of the International Association of Providers of AIDS Care, 2017
In September 2015, the World Health Organization updated their guidelines to recommend antiretroviral therapy (ART) for all people living with HIV. Countries are now in the process of implementing strategies to provide universal HIV treatment.
Kelly A. Hennessey BS, Taina Dadaille Leger MD, Vanessa R. Rivera BS, Adias Marcelin BS, Margaret L. McNairy MD, Colette Guiteau MD, Jessy G. Devieux PhD, Yvel Marcelin BS, Benedict Charles BS, Pierre-Yves Cremieux PhD, Serena P. Koenig, Jean W. Pape   +11 more
doaj   +1 more source