Results 41 to 50 of about 288,869 (302)

Environmental Burkholderia cenocepacia Strain Enhances Fitness by Serial Passages during Long-Term Chronic Airways Infection in Mice [PDF]

, 2017
Burkholderia cenocepacia is an important opportunistic pathogen in cystic fibrosis (CF) patients, and has also been isolated from natural environments. In previous work, we explored the virulence and pathogenic potential of environmental B.
Ascenzioni, Fiorentina, Bevivino, Annamaria, Bragonzi, Alessandra, Coladarci, Ivan, Paroni, Moira, Pirone, Luisa   +5 more
core   +3 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Association between charcoal cooking fuel and cardiovascular disease prevalence in Haiti: a cross-sectional analysis

Environmental Health
Background There is little evidence on the association between cooking with polluting fuels, particularly charcoal, and heart disease from low- and middle-income countries, which have the highest burdens of polluting fuels and cardiovascular disease (CVD)
Lily D. Yan, Rodney Sufra, Reichling St Sauveur, Kelly Celestin, Vanessa Rouzier, Alexandra Apollon, Guyrlaine Forestal, Suzanne Edwidge Marcelin, Sarine Auguste, Josue Pierre, Erline Hilaire, James-Lee Fénélus, Anju Ogyu, Catherine Bennett, Rehana Rasul, Lindsay J. Underhill, Mark D. Huffman, Victor G. Davila-Roman, Jennifer L. Peel, Gene F. Kwan, Marie Marcelle Deschamps, Jean W. Pape, Margaret L. McNairy   +22 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Stakeholder perspectives on barriers and facilitators to hypertension control in urban Haiti: a qualitative study to inform a community-based hypertension management intervention

BMC Public Health
Background Uncontrolled hypertension is the leading modifiable risk factor for cardiovascular disease mortality and remains high in low-middle income countries like Haiti.
Reichling St Sauveur, Rodney Sufra, Marie Christine Jean Pierre, Joseph Inddy, Mirline Jean, Nour Mourra, Radhika Sundararajan, Margaret L. McNairy, Jean W. Pape, Vanessa Rouzier, Jessy Devieux, Lily D. Yan   +11 more
doaj   +1 more source

Cryptococcosis in apparently immune-competent patients: taxonomy, epidemiology, pathophysiology and treatment

Southern African Journal of Infectious Diseases, 2016
No abstract available.
Rachel Wake, Nelesh P. Govender
doaj   +1 more source

Exploring convolutional neural networks and spatial video for on-the-ground mapping in informal settlements

International Journal of Health Geographics, 2021
Background The health burden in developing world informal settlements often coincides with a lack of spatial data that could be used to guide intervention strategies.
Jayakrishnan Ajayakumar, Andrew J. Curtis, Vanessa Rouzier, Jean William Pape, Sandra Bempah, Meer Taifur Alam, Md. Mahbubul Alam, Mohammed H. Rashid, Afsar Ali, John Glenn Morris   +9 more
doaj   +1 more source

Immunodeficiencies caused by infectious diseases. [PDF]

, 2010
Immunodeficiencies caused by infectious agents may result from disruption of normal host barriers or dysregulation of cellular immunity, the latter serving to promote survival of the infectious agent through immune evasion.
Sykes, Jane
core  

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

Incidence of WHO stage 3 and 4 conditions following initiation of Anti-Retroviral Therapy in resource limited settings [PDF]

, 2012
To determine the incidence of WHO clinical stage 3 and 4 conditions during early anti-retroviral therapy (ART) in resource limited settings (RLS)
A d’Arminio Monforte, A Miranda, Andrea J. Curtis, AS Walker, B Castelnuovo, B Ledergerber, Catherine S. Marshall, CE Gonzalez, Daniel P. O’Brien, DJ Sloan, DR Hoover, Esther C. Casas, J Abadi, J Mermin, Jane Greig, JE Golub, JE Kaplan, JF Etard, Julian H. Elliot, K Buchacz, Leslie Shanks, M-L Newell, Marcio Silveria Da Fonseca, NJ Ives, Philipp Du Cros, R Zachariah, SD Lawn, Sten H. Vermund, Tim Spelman, VO Kasprowicz, W Manosuthi   +30 more
core   +7 more sources