Results 51 to 60 of about 288,869 (302)

High Burden of Cardiovascular Disease and Mental Health Illness Comorbidity in Urban Haiti

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background People living in low‐income settings facing humanitarian crises are at risk for comorbid cardiovascular disease (CVD) and mental health (MH) illness, yet there are limited population‐based data available.
Lily D. Yan, Miranda Metz, Rodney Sufra, Reichling St Sauveur, Kelly Celestin, Erline Hilaire, Suzanne Edwidge Marcellin, Sarine Auguste, Anju Ogyu, Catherine Bennett, Serena Koenig, Lindsey Reif, Jessy Dévieux, Marie Marcelle Deschamps, Jean W. Pape, Vanessa Rouzier, Margaret L. McNairy   +16 more
doaj   +1 more source

Staphylococcus aureus bacteraemia in Gauteng academic hospitals, South Africa

International Journal of Infectious Diseases, 2015
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) infections are responsible for longer hospital stays, increased hospital costs, and poorer outcomes compared to methicillin-sensitive S. aureus (MSSA) infections.
Melony C. Fortuin-de Smidt, Ashika Singh-Moodley, Rubeina Badat, Vanessa Quan, Ranmini Kularatne, Trusha Nana, Ruth Lekalakala, Nelesh P. Govender, Olga Perovic   +8 more
doaj   +1 more source

Prevalence and distribution of Entamoeba species in a rural community in northern South Africa

Food and Waterborne Parasitology, 2020
Amoebiasis occurs worldwide and affects about 20–50 million people annually. Stool samples were collected from patients attending different rural clinics in Northern South Africa in the present study. Microscopic examination was performed for the initial
Amidou Samie, Leah Mahlaule, Peter Mbati, Tomoyoshi Nozaki, Ali ElBakri   +4 more
doaj   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) Network investigators   +14 more
wiley   +1 more source

Expansion of neopterin and beta2-microglobulin in cerebrospinal fluid reaches maximum levels early and late in the course of human immunodeficiency virus infection [PDF]

, 1992
Inhaltsverzeichnis ...
Bogner, Johannes R., Goebel, Frank-Detlef, Junge-Hülsing, B., Kronawitter, Ursula, Matuschke, A., Sadri, Ifna   +5 more
core   +1 more source

Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis

Advanced Science, EarlyView.
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen, Hao Shi, Junxian He, Ziyu Liu, Yuanyuan Zhu, Xiaoyan Liang, Guihua Liu, Xing Yang   +7 more
wiley   +1 more source

Effectiveness of community‐based hypertension management on hypertension in the urban slums of Haiti: A mixed methods study

The Journal of Clinical Hypertension
Hypertension is a leading contributor to mortality in low‐middle income countries including Haiti, yet only 13% achieve blood pressure (BP) control.
Reichling St Sauveur, Rodney Sufra, Marie Christine Jean Pierre, Vanessa Rouzier, Fabiola Preval, Serfine Exantus, Mirline Jean, Josette Jean, Guyrlaine Pierre‐Louise Forestal, Obed Fleurijean, Nour Mourra, Anju Ogyu, Rodolphe Malebranche, Jean Pierre Brisma, Marie M. Deschamps, Jean W. Pape, Radhika Sundararajan, Margaret L. McNairy, Lily D. Yan   +18 more
doaj   +1 more source

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

Advanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen, Ruqiao Duan, Cunzheng Zhang, Gaonan Li, XiaoLin Ji, Qi Zhang, Fei Pei, Kun Wang, Liping Duan   +8 more
wiley   +1 more source

Prevalence and genetic characterization of Giardia lamblia in relation to diarrhea in Limpopo and Gauteng provinces, South Africa

Parasite Epidemiology and Control, 2020
Background: Very few studies have determined the prevalence and assemblage distribution of Giardia lamblia in South Africa. The present study aimed to ascertain the prevalence of G.
Amidou Samie, Nicoline F. Tanih, Itumeleng Seisa, Mapaseka Seheri, Jeffrey Mphahlele, Ali ElBakri, Peter Mbati   +6 more
doaj   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source