Results 31 to 40 of about 140,857 (270)

Insecticide resistance in the malaria vector Anopheles arabiensis in Mamfene, KwaZulu-Natal

open access: yesSouth African Journal of Science, 2015
The control of malaria vector mosquitoes in South Africa’s affected provinces is primarily based on indoor spraying of long-lasting residual insecticides. The primary vectors in South Africa are Anopheles arabiensis and An. funestus.
Basil D. Brook   +7 more
doaj   +1 more source

Exploring convolutional neural networks and spatial video for on-the-ground mapping in informal settlements

open access: yesInternational Journal of Health Geographics, 2021
Background The health burden in developing world informal settlements often coincides with a lack of spatial data that could be used to guide intervention strategies.
Jayakrishnan Ajayakumar   +9 more
doaj   +1 more source

Detection of virulence factors and beta-lactamase encoding genes among the clinical isolates of Pseudomonas aeruginosa [PDF]

open access: yesInternational Journal of Pharmaceutical Research, 2019, 2019
Background: Pseudomonas aeruginosa has emerged as a significant opportunistic bacterial pathogen that causes nosocomial infections in healthcare settings resulting in treatment failure throughout the world. This study was carried out to compare the relatedness between virulence characteristics and \b{eta}-lactamase encoding genes producing Pseudomonas ...
arxiv   +1 more source

Cryptococcosis in apparently immune-competent patients: taxonomy, epidemiology, pathophysiology and treatment

open access: yesSouthern African Journal of Infectious Diseases, 2016
No abstract available.
Rachel Wake, Nelesh P. Govender
doaj   +1 more source

Novel Approaches To Design Glycan‐Based Antibacterial Inhibitors

open access: yesEuropean Journal of Organic Chemistry, Volume 26, Issue 1, January 2, 2023., 2023
Sweet and sticky: This review describes recent advances in the synthesis and application of homo‐and heterovalent glycan‐scaffolds as potential candidates for efficient bacteria lectin inhibition. To study and address the many complex molecular mechanisms involved in multivalent lectin binding events, novel glycoconjugate designs and fine‐tunable ...
Sandra Behren, Ulrika Westerlind
wiley   +1 more source

A Systemic Receptor Network Triggered by Human cytomegalovirus Entry [PDF]

open access: yesAdvances in Virology Volume 2011 (2011), Article ID 262080, 11 pages, 2010
Virus entry is a multistep process that triggers a variety of cellular pathways interconnecting into a complex network, yet the molecular complexity of this network remains largely unsolved. Here, by employing systems biology approach, we reveal a systemic virus-entry network initiated by human cytomegalovirus (HCMV), a widespread opportunistic ...
arxiv   +1 more source

Staphylococcus aureus bacteraemia in Gauteng academic hospitals, South Africa

open access: yesInternational Journal of Infectious Diseases, 2015
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) infections are responsible for longer hospital stays, increased hospital costs, and poorer outcomes compared to methicillin-sensitive S. aureus (MSSA) infections.
Melony C. Fortuin-de Smidt   +8 more
doaj   +1 more source

Early initiation of fast‐track care for persons living with HIV initiating dolutegravir‐based regimens during a period of severe civil unrest in Port‐au‐Prince, Haiti: a pilot randomized trial

open access: yesJournal of the International AIDS Society
Introduction Differentiated service delivery (DSD) models have been widely implemented for patients in stable HIV care. However, DSD has rarely been offered to newly diagnosed patients.
Jean Bernard Marc   +18 more
doaj   +1 more source

Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins

open access: yesFEBS Open Bio, EarlyView.
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet   +6 more
wiley   +1 more source

Antibacterial Siderophores of Pandoraea Pathogens and Their Impact on the Diseased Lung Microbiota

open access: yesAngewandte Chemie, EarlyView.
Genome mining of environmental and pathogenic Pandoraea species identified a conserved NRPS gene cluster and led to the discovery of novel siderophores, pandorabactins, which exert their antibacterial activity by depleting iron from competitors. Bioinformatic analysis of sputum from cystic fibrosis patients coupled with bioassays indicates that ...
Elena Herzog   +8 more
wiley   +2 more sources

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