Results 31 to 40 of about 140,857 (270)
Insecticide resistance in the malaria vector Anopheles arabiensis in Mamfene, KwaZulu-Natal
The control of malaria vector mosquitoes in South Africa’s affected provinces is primarily based on indoor spraying of long-lasting residual insecticides. The primary vectors in South Africa are Anopheles arabiensis and An. funestus.
Basil D. Brook+7 more
doaj +1 more source
Background The health burden in developing world informal settlements often coincides with a lack of spatial data that could be used to guide intervention strategies.
Jayakrishnan Ajayakumar+9 more
doaj +1 more source
Detection of virulence factors and beta-lactamase encoding genes among the clinical isolates of Pseudomonas aeruginosa [PDF]
Background: Pseudomonas aeruginosa has emerged as a significant opportunistic bacterial pathogen that causes nosocomial infections in healthcare settings resulting in treatment failure throughout the world. This study was carried out to compare the relatedness between virulence characteristics and \b{eta}-lactamase encoding genes producing Pseudomonas ...
arxiv +1 more source
No abstract available.
Rachel Wake, Nelesh P. Govender
doaj +1 more source
Novel Approaches To Design Glycan‐Based Antibacterial Inhibitors
Sweet and sticky: This review describes recent advances in the synthesis and application of homo‐and heterovalent glycan‐scaffolds as potential candidates for efficient bacteria lectin inhibition. To study and address the many complex molecular mechanisms involved in multivalent lectin binding events, novel glycoconjugate designs and fine‐tunable ...
Sandra Behren, Ulrika Westerlind
wiley +1 more source
A Systemic Receptor Network Triggered by Human cytomegalovirus Entry [PDF]
Virus entry is a multistep process that triggers a variety of cellular pathways interconnecting into a complex network, yet the molecular complexity of this network remains largely unsolved. Here, by employing systems biology approach, we reveal a systemic virus-entry network initiated by human cytomegalovirus (HCMV), a widespread opportunistic ...
arxiv +1 more source
Staphylococcus aureus bacteraemia in Gauteng academic hospitals, South Africa
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) infections are responsible for longer hospital stays, increased hospital costs, and poorer outcomes compared to methicillin-sensitive S. aureus (MSSA) infections.
Melony C. Fortuin-de Smidt+8 more
doaj +1 more source
Introduction Differentiated service delivery (DSD) models have been widely implemented for patients in stable HIV care. However, DSD has rarely been offered to newly diagnosed patients.
Jean Bernard Marc+18 more
doaj +1 more source
Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet+6 more
wiley +1 more source
Antibacterial Siderophores of Pandoraea Pathogens and Their Impact on the Diseased Lung Microbiota
Genome mining of environmental and pathogenic Pandoraea species identified a conserved NRPS gene cluster and led to the discovery of novel siderophores, pandorabactins, which exert their antibacterial activity by depleting iron from competitors. Bioinformatic analysis of sputum from cystic fibrosis patients coupled with bioassays indicates that ...
Elena Herzog+8 more
wiley +2 more sources