Results 61 to 70 of about 6,863,082 (290)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

The Geography of Rural Educational Opportunity

RSF: The Russell Sage Foundation Journal of the Social Sciences, 2022
We use nearly 430 million standardized test scores, including test scores from more than 6,500 rural school districts, to describe educational opportunity in rural America.
Jessica Drescher, Anne Podolsky, Sean F. Reardon, Gabrielle Torrance   +3 more
doaj   +1 more source

From Opportunity to Status [PDF]

, 1976
[Excerpt] When Ronald Knox, at the age of four, was asked what he did for his insomnia, he replied, I lie awake and think about the past. I suspect that even the future celebrated biblical scholar did not, at the age of four, have much of a past to ...
Konvitz, Milton R
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Opportunities [PDF]

The Linacre Quarterly, 2019
  +9 more sources

Political Integration in Practice: Explaining a Time-Dependent Increase in Political Knowledge among Immigrants in Sweden

Social Inclusion, 2018
Scholarly findings suggest that immigrants in Western countries, in general, participate less in politics and show lower levels of political efficacy than native-born citizens.
Per Adman, Per Strömblad
doaj   +1 more source

Housing, Neighborhoods, and Opportunity [PDF]

, 2006
Opportunities for homeownership "which have historically been limited for some racial and ethnic minority groups and low-income families" are strongly linked to wealth creation and financial security.

core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Criminal Justice and Opportunity [PDF]

, 2006
Today, many criminal justice policies and practices have closed the door to opportunity. Whole communities suffer opportunity losses when large segments of residents are involved in the criminal justice system.

core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source