Results 71 to 80 of about 6,843,786 (291)
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
African Americans and Opportunity [PDF]
Despite considerable progress over the last several decades, African Americans continue to face many barriers to opportunity Find out how African Americans are faring along our 6 dimensions of ...
core
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
We examine the themes of equal opportunity, intergenerational mobility, and inequality. We address the normative and definitional questions of selecting measures of mobility and summarize the current state of intergenerational mobility in the United ...
Isabel V. Sawhill, Richard V. Reeves
doaj +1 more source
Health Care and Opportunity [PDF]
Tens of millions of Americans experience barriers to accessing appropriate health care, and many more face inequitable, lower-quality care that carries a heavy human and economic toll.
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
An empirical analysis of asset misappropriation fraud during the COVID-19 crisis [PDF]
The objective of this paper is to examine asset misappropriation fraud during the COVID-19 pandemic. The study examines the impact of four elements of fraud risk factors and Islamic religiosity on the propensity for fraud among employees who manage ...
Darsono Darsono +4 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Progresses and challenges in the traditional medicine information system: A systematic review [PDF]
Context: Traditional medicine information system (TMIS) is a substructure founded on the targeted application of technology. It also serves as a tool supporting the decisions in traditional medicine (TM). However, due to following a different approach in
Razieh Mirzaeian +3 more
doaj

