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We examine the themes of equal opportunity, intergenerational mobility, and inequality. We address the normative and definitional questions of selecting measures of mobility and summarize the current state of intergenerational mobility in the United ...
Isabel V. Sawhill, Richard V. Reeves
doaj +1 more source
RAM Opportunity is a self-sustaining mentoring and experiential learning program designed to serve high school students in the local community through programs led by graduate student mentors. RAM Opportunity operates using a plug-and-play structure that
at Virginia Commonwealth University, The Grace E. Harris Leadership Institute +7 more
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
An empirical analysis of asset misappropriation fraud during the COVID-19 crisis [PDF]
The objective of this paper is to examine asset misappropriation fraud during the COVID-19 pandemic. The study examines the impact of four elements of fraud risk factors and Islamic religiosity on the propensity for fraud among employees who manage ...
Darsono Darsono +4 more
doaj +1 more source
Low Income Families and Opportunity [PDF]
Despite considerable progress over last several decades, low-income families continue to face many barriers to opportunity. In 2004 the number and rate of people in poverty increased for the fourth consecutive year. This is just one sign that opportunity
core
What is equality of opportunity in education? [PDF]
There is widespread disagreement about what equality of opportunity in education requires. For some it is that each child is legally permitted to go to school. For others it is that each child receives the same educational resources.
Lazenby, Hugh
core +1 more source
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Progresses and challenges in the traditional medicine information system: A systematic review [PDF]
Context: Traditional medicine information system (TMIS) is a substructure founded on the targeted application of technology. It also serves as a tool supporting the decisions in traditional medicine (TM). However, due to following a different approach in
Razieh Mirzaeian +3 more
doaj
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source

