Results 71 to 80 of about 115,781 (240)

Russian Empire’s Monitoring of Turkish-Kazakh and Dzungar-Kalmyk Diplomatic Relations and It’s Methods of Countering Them in the 1730-1740s

open access: yesRUDN Journal of Russian History
One of the consequences of Kazakh zhuzes’ and the Kalmyk Khanate’s joining Russia was supposedly their rulers’ abandonment of independent foreign policy.
Stepan V. Dzhundzhuzov
doaj   +1 more source

The position of the Iranian press on the internal developments in Iran 1918-1925 AD in the light of Persian documents, a study in models

open access: yesآداب الكوفة, 2016
Enjoyed the press and those who made it in Iran a kind of relative freedom during the first phase of old and evolved that movement during the years of the Constitutional Movement, and increased confidence and maturity during the years of the First World
Aladdin al-Hakim, Ahmed Alalaq
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Relationships between Opposition and Powers in Tajikistan:History and Present Time

open access: yesПроблемы постсоветского пространства, 2017
After becoming independent the relationships between the official powers of Tajikistan and oppo- sition were shaping not easily. The opposition was, in fact, estranged from development and implementation of internal and foreign policy.
H. H. Khurramov
doaj  

The Iranian Kurdistan Democratic Party 1963-1979 AD

open access: yesآداب الكوفة, 2012
The Iranian Kurdistan Democratic Party is considered one of the nationalist parties that the Iranian political scene witnessed, starting from the year of its founding in 1945 until the banning of political parties in 1979 AD, with the victory of the ...
Ali Muhammad, Ahmed Alalaq
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

L’opposition au cœur de l’analyse des sports collectifs

open access: yeseJournal de la Recherche sur l'Intervention en Éducation Physique et Sport, 2019
In team sports, the primary rules of the game are based on the logic of the game itself. The main characteristic is the systematic opposition relationship between attack and defense.
Eric Duprat
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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