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Roadmap for direct and indirect translation of optogenetics into discoveries and therapies for humans. [PDF]
Lüscher C +10 more
europepmc +1 more source
Efficient derivation of hiPSC-derived photoreceptor precursor cells and their neuroprotective effects in retinal degeneration. [PDF]
Du Y +8 more
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Pineal Opsin: a Nonvisual Opsin Expressed in Chick Pineal
Science, 1995Pineal opsin (P-opsin), an opsin from chick that is highly expressed in pineal but is not detectable in retina, was cloned by the polymerase chain reaction. It is likely that the P-opsin lineage diverged from the retinal opsins early in opsin evolution. The amino acid sequence of P-opsin is 42 to 46 percent identical to that of the retinal opsins.
M, Max +6 more
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2018
This case will examine the evolution of trichromatic vision in old world monkeys.
White, Peter +4 more
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This case will examine the evolution of trichromatic vision in old world monkeys.
White, Peter +4 more
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Optogenetic Potentials of Diverse Animal Opsins: Parapinopsin, Peropsin, LWS Bistable Opsin
2021Animal opsin-based pigments are light-activated G-protein-coupled receptors (GPCRs), which drive signal transduction cascades via G-proteins. Thousands of animal opsins have been identified, and molecular phylogenetic and biochemical analyses have revealed the unexpected diversity in selectivity of G-protein activation and photochemical property.
Mitsumasa, Koyanagi +5 more
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Opsins and mammalian photoentrainment
Cell and Tissue Research, 2002Research over the past decade has provided overwhelming evidence that photoreception in the vertebrate eye is not confined to the rod and cone photoreceptors. It appears that photoreceptor cells within the inner retina provide irradiance information to a wide variety of different photosensory tasks including photoentrainment, pupillary constriction and
Bellingham, James, Foster, Russell G.
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Opsin for immunological studies
Current Eye Research, 1985Opsin for immunological studies can be prepared free from S-antigen by affinity chromatography on Con A-Sepharose. This preparation, however, contains 2-6% Con A originating from the affinity medium. Con A as impurity disturbs lymphocyte transformation tests carried out with opsin as test antigen. We describe a method for the removal of Con A by immuno-
R M, Broekhuyse, E D, Kuhlmann
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A radioimmunoassay specific for opsin
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1983A radioimmunoassay is developed for bovine opsin using a rabbit antiserum against bovine rod outer segment membranes. The assay is specific for opsin. Rhodopsin, bacteriorhodopsin and hemoglobin do not show cross-reaction. It can be carried out rapidly, has a sensitivity of 0.01 pmol bovine opsin and gives accurate results, even in the presence of a ...
J J, Schalken +3 more
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