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Optogenetics: Background, Methodological Advances and Potential Applications for Cardiovascular Research and Medicine [PDF]

open access: yes, 2020
Optogenetics is an elegant approach of precisely controlling and monitoring the biological functions of a cell, group of cells, tissues, or organs with high temporal and spatial resolution by using optical system and genetic engineering technologies. The
Joshi, Jyotsna   +2 more
core   +1 more source

Retinal cone photoreceptors of the deer mouse Peromyscus maniculatus : development, topography, opsin expression and spectral tuning [PDF]

open access: yes, 2013
A quantitative analysis of photoreceptor properties was performed in the retina of the nocturnal deer mouse, Peromyscus maniculatus, using pigmented (wildtype) and albino animals.
Arbogast, Patrick   +2 more
core   +2 more sources

The two-photon reversible reaction of the bistable jumping spider rhodopsin-1 [PDF]

open access: yes, 2019
Bistable opsins are photopigments expressed in both invertebrates and vertebrates. These light-sensitive G-protein-coupled receptors undergo a reversible reaction upon illumination.
Deupi, Xavier   +7 more
core   +1 more source

Precise multimodal optical control of neural ensemble activity. [PDF]

open access: yes, 2018
Understanding brain function requires technologies that can control the activity of large populations of neurons with high fidelity in space and time. We developed a multiphoton holographic approach to activate or suppress the activity of ensembles of ...
Adesnik, Hillel   +8 more
core   +1 more source

Evolutionary ecology of opsin gene sequence, expression and repertoire. [PDF]

open access: yes, 2017
Linking molecular evolution to biological function is a long-standing challenge in evolutionary biology. Some of the best examples of this involve opsins, the genes that encode the molecular basis of light reception.
Owens, Gregory L, Rennison, Diana J
core   +1 more source

Tools for Controlling Activity of Neural Circuits Can Boost Gastrointestinal Research [PDF]

open access: yes, 2016
We thank Prof U. G. Knaus and T. C. Collin for critical reading of the manuscript. GA is supported by the European Crohn's and Colitis Organization (ECCO) (J/15/2) and by the National Childrens' Research Centre (K/12/1). GD is supported by the University
Aviello, Gabriella, D'Agostino, Giuseppe
core   +8 more sources

Opsin expression predicts male nuptial color in threespine stickleback. [PDF]

open access: yes, 2018
Theoretical models of sexual selection suggest that male courtship signals can evolve through the build-up of genetic correlations between the male signal and female preference.
Bolnick, Daniel I   +3 more
core   +2 more sources

New Tardigrade Opsins and Differential Expression Analyses Show Ontogenic Variation in Light Perception [PDF]

open access: yes, 2021
Opsins are light-sensitive proteins involved in many photoreceptive processes, including, but not limited to, vision and regulation of circadian rhythms.
Arakawa, Kazuharu   +2 more
core   +1 more source

Blue light regenerates functional visual pigments in mammals through a retinyl-phospholipid intermediate. [PDF]

open access: yes, 2017
The light absorbing chromophore in opsin visual pigments is the protonated Schiff base of 11-cis-retinaldehyde (11cRAL). Absorption of a photon isomerizes 11cRAL to all-trans-retinaldehyde (atRAL), briefly activating the pigment before it dissociates ...
Fain, Gordon L   +6 more
core   +1 more source

Rpgrip1 is required for rod outer segment development and ciliary protein trafficking in zebrafish [PDF]

open access: yes, 2017
The authors would like to thank the Royal Society of London, the National Eye Research Centre, the Visual Research Trust, Fight for Sight, the W.H. Ross Foundation, the Rosetrees Trust, and the Glasgow Children’s Hospital Charity for supporting this work.
A Eblimit   +54 more
core   +4 more sources

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