Results 1 to 10 of about 18,496 (258)

Discovery and design of photocyclic animal opsins: potential application to gene therapy from non-visual opsin research [PDF]

Eye and Vision
Opsins are universal photoreceptive proteins in animals. Rhodopsin is the best-studied opsin and functions as a visual sensor in rod cells of human and mouse retinas.
Takahiro Yamashita
doaj   +2 more sources

Dragonfly red opsins share a common tuning mechanism with mammalian red opsins and further enhancement of near-infrared sensitivity [PDF]

Cellular and Molecular Life Sciences
Some animals, such as primates and insects have color vision including sensitivity to red light (red vision). Red vision is basically achieved through opsins sensitive to the red region (red opsins), which independently evolved in different lineages.
Ryu Sato, Akihisa Terakita, Mitsumasa Koyanagi   +2 more
doaj   +2 more sources

Light and myopia: a focus on the expanding role of non-visual opsins [PDF]

Eye and Vision
Myopia, or near-sightedness, is a growing global concern as its incidence rate continues to dramatically rise. It has been linked to significant ocular morbidity and reduced quality of life.
Kate Gettinger, Kazuo Tsubota, Kazuno Negishi, Toshihide Kurihara   +3 more
doaj   +2 more sources

Molecular diversity of protostome non-visual opsin arthropsin [PDF]

iScience
Summary: Opsins underlie visual and non-visual photoreceptions in animals. Vertebrate and arthropod visual opsins belong to different opsin groups and convergently show spectral diversity ranging from the UV to the red region for color vision.
Takahiro Yamashita, Kengo Fujii, Chihiro Fujiyabu, Kazumi Sakai, Yasuhiro Shiga   +4 more
doaj   +2 more sources

Coral anthozoan-specific opsins employ a novel chloride counterion for spectral tuning

eLife
Animal opsins are G protein-coupled receptors that have evolved to sense light by covalently binding a retinal chromophore via a protonated (positively charged) Schiff base. A negatively charged amino acid in the opsin, acting as a counterion, stabilizes
Yusuke Sakai, Saumik Sen, Tomohiro Sugihara, Yukiya Kakeyama, Makoto Iwasaki, Gebhard FX Schertler, Xavier Deupi, Mitsumasa Koyanagi, Akihisa Terakita   +8 more
doaj   +2 more sources

The Gluopsins: Opsins without the Retinal Binding Lysine

Cells, 2022
Opsins allow us to see. They are G-protein-coupled receptors and bind as ligand retinal, which is bound covalently to a lysine in the seventh transmembrane domain. This makes opsins light-sensitive.
Martin Gühmann, Megan L. Porter, Michael J. Bok   +2 more
doaj   +1 more source

The evolution of opsin genes in five species of mirid bugs: duplication of long-wavelength opsins and loss of blue-sensitive opsins

BMC Ecology and Evolution, 2021
Background Color vision and phototactic behavior based on opsins are important for the fitness of insects because of their roles in foraging and mate choice.
Pengjun Xu, Bin Lu, Jiangtao Chao, Robert Holdbrook, Gemei Liang, Yanhui Lu   +5 more
doaj   +1 more source

Opsins as main regulators of skin biology

Journal of Photochemistry and Photobiology, 2023
Opsins are light-sensitive proteins that are found across the animal kingdom. In mammals, opsins are classically associated with image-forming processes, a function exerted by cone and rod opsins.
Ana Maria de Lauro Castrucci, Maurício S. Baptista, Leonardo Vinicius Monteiro de Assis   +2 more
doaj   +1 more source

A Large and Phylogenetically Diverse Class of Type 1 Opsins Lacking a Canonical Retinal Binding Site. [PDF]

PLoS ONE, 2016
Opsins are photosensitive proteins catalyzing light-dependent processes across the tree of life. For both microbial (type 1) and metazoan (type 2) opsins, photosensing depends upon covalent interaction between a retinal chromophore and a conserved lysine
Erin A Becker, Andrew I Yao, Phillip M Seitzer, Tobias Kind, Ting Wang, Rich Eigenheer, Katie S Y Shao, Vladimir Yarov-Yarovoy, Marc T Facciotti   +8 more
doaj   +1 more source

Genetic Constructs for the Control of Astrocytes’ Activity

Cells, 2021
In the current review, we aim to discuss the principles and the perspectives of using the genetic constructs based on AAV vectors to regulate astrocytes’ activity.
Anastasia A. Borodinova, Pavel M. Balaban, Ilya B. Bezprozvanny, Alla B. Salmina, Olga L. Vlasova   +4 more
doaj   +1 more source