Results 41 to 50 of about 15,921 (237)

A Go-type opsin mediates the shadow reflex in the annelid Platynereis dumerilii

BMC Biology, 2018
Background The presence of photoreceptive molecules outside the eye is widespread among animals, yet their functions in the periphery are less well understood.
Thomas Ayers, Hisao Tsukamoto, Martin Gühmann, Vinoth Babu Veedin Rajan, Kristin Tessmar-Raible   +4 more
doaj   +1 more source

Optogenetic Gene Therapy for the Degenerate Retina: Recent Advances

Frontiers in Neuroscience, 2020
The degeneration of light-detecting rod and cone photoreceptors in the human retina leads to severe visual impairment and ultimately legal blindness in millions of people worldwide.
Michelle E. McClements, Federica Staurenghi, Robert E. MacLaren, Robert E. MacLaren, Jasmina Cehajic-Kapetanovic, Jasmina Cehajic-Kapetanovic   +5 more
doaj   +1 more source

Activation of Transducin by Bistable Pigment Parapinopsin in the Pineal Organ of Lower Vertebrates. [PDF]

PLoS ONE, 2015
Pineal organs of lower vertebrates contain several kinds of photosensitive molecules, opsins that are suggested to be involved in different light-regulated physiological functions. We previously reported that parapinopsin is an ultraviolet (UV)-sensitive
Emi Kawano-Yamashita, Mitsumasa Koyanagi, Seiji Wada, Hisao Tsukamoto, Takashi Nagata, Akihisa Terakita   +5 more
doaj   +1 more source

Spectral tuning mediated by helix III in butterfly long wavelength-sensitive visual opsins revealed by heterologous action spectroscopy

Zoological Letters, 2019
Absorption spectra of opsin-based pigments are tuned from the UV to the red regions by interactions of the chromophore with surrounding amino acid residues. Both vertebrates and invertebrates possess long-wavelength-sensitive (LWS) opsins, which underlie
Tomoka Saito, Mitsumasa Koyanagi, Tomohiro Sugihara, Takashi Nagata, Kentaro Arikawa, Akihisa Terakita   +5 more
doaj   +1 more source

Nematostella vectensis exemplifies the exceptional expansion and diversity of opsins in the eyeless Hexacorallia

EvoDevo, 2023
Background Opsins are the primary proteins responsible for light detection in animals. Cnidarians (jellyfish, sea anemones, corals) have diverse visual systems that have evolved in parallel with bilaterians (squid, flies, fish) for hundreds of millions ...
Kyle J. McCulloch, Leslie S. Babonis, Alicia Liu, Christina M. Daly, Mark Q. Martindale, Kristen M. Koenig   +5 more
doaj   +1 more source

Molecular evidence that only two opsin subfamilies, the blue light- (SWS2) and green light-sensitive (RH2), drive color vision in Atlantic cod (Gadus morhua). [PDF]

PLoS ONE, 2014
Teleosts show a great variety in visual opsin complement, due to both gene duplication and gene loss. The repertoire ranges from one subfamily of visual opsins (scotopic vision) including rod opsin only retinas seen in many deep-sea species to multiple ...
Ragnhild Valen, Rolf Brudvik Edvardsen, Anne Mette Søviknes, Øyvind Drivenes, Jon Vidar Helvik   +4 more
doaj   +1 more source

Palmitoylation stabilizes unliganded rod opsin [PDF]

Proceedings of the National Academy of Sciences, 2010
S-palmitoylation is a conserved feature in many G protein–coupled receptors (GPCRs) involved in a broad array of signaling processes. The prototypical GPCR, rhodopsin, is S-palmitoylated on two adjacent C-terminal Cys residues at its cytoplasmic surface.
Akiko, Maeda, Kiichiro, Okano, Paul S-H, Park, Janis, Lem, Rosalie K, Crouch, Tadao, Maeda, Krzysztof, Palczewski   +6 more
openaire   +2 more sources

Molecular diversity of protostome non-visual opsin arthropsin

iScience
Summary: Opsins underlie visual and non-visual photoreceptions in animals. Vertebrate and arthropod visual opsins belong to different opsin groups and convergently show spectral diversity ranging from the UV to the red region for color vision.
Takahiro Yamashita, Kengo Fujii, Chihiro Fujiyabu, Kazumi Sakai, Yasuhiro Shiga   +4 more
doaj   +1 more source

TMT-Opsins differentially modulate medaka brain function in a context-dependent manner.

PLoS Biology, 2021
Vertebrate behavior is strongly influenced by light. Light receptors, encoded by functional opsin proteins, are present inside the vertebrate brain and peripheral tissues.
Bruno M Fontinha, Theresa Zekoll, Mariam Al-Rawi, Miguel Gallach, Florian Reithofer, Alison J Barker, Maximilian Hofbauer, Ruth M Fischer, Arndt von Haeseler, Herwig Baier, Kristin Tessmar-Raible   +10 more
doaj   +1 more source

Localized Temperature Monitoring in Mouse Brain during Light Delivery via a Non‐Planar Tapered Fiber‐Integrated µRTD Sensor

Advanced Materials, EarlyView.
We report a multifunctional tapered optical fiber integrating a conformal micro‐resistance temperature detector (µRTD) for local, real‐time thermometry during optical stimulation. The platform combines light‐delivery and temperature sensing within a minimally invasive footprint, enabling detection of sub‐degree cortical heating under representative ...
Antonio Balena, Marco Bianco, Barbara Spagnolo, Muhammad Fayyaz Kashif, Alberto Bramati, Massimo De Vittorio, Ferruccio Pisanello   +6 more
wiley   +1 more source