Results 1 to 10 of about 78,413 (264)

Pore Forming Properties of Cecropin-Melittin Hybrid Peptide in a Natural Membrane

Molecules, 2009
The pore forming properties of synthetic cecropin-melittin hybrid peptide (Acetyl-KWKLFKKIGAVLKVL-CONH2; CM15) were investigated by using photoreceptor rod outer segments (OS) isolated from frog retinae obtained by using the whole-cell configuration of ...
Giorgio Rispoli, Marco Aquila, Alberto Milani, Mascia Benedusi   +3 more
doaj   +1 more source

Functionally Assessing the Age-Related Decline in the Detection Rate of Photons by Cone Photoreceptors

Frontiers in Aging Neuroscience, 2021
Age-related decline in visual perception is usually attributed to optical factors of the eye and neural factors. However, the detection of light by cones converting light into neural signals is a crucial intermediate processing step of vision ...
Asma Braham chaouche, Maryam Rezaei, Daphné Silvestre, Angelo Arleo, Rémy Allard   +4 more
doaj   +1 more source

Synaptic Remodeling in the Cone Pathway After Early Postnatal Horizontal Cell Ablation

Frontiers in Cellular Neuroscience, 2021
The first synapse of the visual pathway is formed by photoreceptors, horizontal cells and bipolar cells. While ON bipolar cells invaginate into the photoreceptor terminal and form synaptic triads together with invaginating horizontal cell processes, OFF ...
Lena Nemitz, Karin Dedek, Karin Dedek, Ulrike Janssen-Bienhold, Ulrike Janssen-Bienhold   +4 more
doaj   +1 more source

A Defective Crosstalk Between Neurons and Müller Glial Cells in the rd1 Retina Impairs the Regenerative Potential of Glial Stem Cells

Frontiers in Cellular Neuroscience, 2019
Müller glial cells (MGC) are stem cells in the retina. Although their regenerative capacity is very low in mammals, the use of MGC as stem cells to regenerate photoreceptors (PHRs) during retina degenerations, such as in retinitis pigmentosa, is being ...
Yanel A. Volonté, Harmonie Vallese-Maurizi, Marcos J. Dibo, Victoria B. Ayala-Peña, Andrés Garelli, Samanta R. Zanetti, Axel Turpaud, Cheryl Mae Craft, Cheryl Mae Craft, Nora P. Rotstein, Luis E. Politi, Olga L. German   +11 more
doaj   +1 more source

Transplanted human photoreceptors transfer cytoplasmic material but not to the recipient mouse retina

Stem Cell Research & Therapy
Background The discovery of material transfer between transplanted and host mouse photoreceptors has expanded the possibilities for utilizing transplanted photoreceptors as potential vehicles for delivering therapeutic cargo.
Margaret T. Ho, Kotoe Kawai, Dhana Abdo, Lacrimioara Comanita, Arturo Ortin-Martinez, Yui Ueno, Emily Tsao, Azam Rastgar-Moghadam, Chang Xue, Hong Cui, Valerie A. Wallace, Molly S. Shoichet   +11 more
doaj   +1 more source

High-Blue/Low-Red Mixed Light Modulates Photoperiodic Flowering in Chrysanthemum via Photoreceptor and Sugar Pathways

Plants
Chrysanthemum (Chrysanthemum morifolium Ramat.), a typical short-day plant (SDP), relies on photoperiod and light quality signals to regulate flowering and growth.
Jingli Yang, Zhengyang Cheng, Jinnan Song, Byoung Ryong Jeong   +3 more
doaj   +1 more source

Age-dependent changes of monocarboxylate transporter 8 availability in the postnatal murine retina

Frontiers in Cellular Neuroscience, 2016
The thyroid hormones (TH) triiodothyronine (T3) and its prohormone thyroxine (T4) are crucial for retinal development and function, and increasing evidence points at TH dysregulation as a cause for retinal degenerative diseases.
Yoshiyuki Henning, Karol Szafranski
doaj   +1 more source

Local Insulin for Local Needs? Insights into Retinal Insulin Signaling and RPE Metabolism

Biomolecules
Insulin is a key anabolic hormone traditionally considered to be exclusively produced by pancreatic β-cells. Insulin exerts several systemic effects involved in glucose uptake and metabolism.
Matilde Balbi, Alessandra Puddu, Andrea Amaroli, Davide Maggi, Isabella Panfoli, Silvia Ravera   +5 more
doaj   +1 more source

The Na+/Ca2+, K+ exchanger NCKX4 is required for efficient cone-mediated vision

eLife, 2017
Calcium (Ca2+) plays an important role in the function and health of neurons. In vertebrate cone photoreceptors, Ca2+ controls photoresponse sensitivity, kinetics, and light adaptation.
Frans Vinberg, Tian Wang, Alicia De Maria, Haiqing Zhao, Steven Bassnett, Jeannie Chen, Vladimir J Kefalov   +6 more
doaj   +1 more source

Two Decades of Optogenetic Tools: A Retrospective and a Look Ahead

Advanced Genetics
Over the past two decades, optogenetics has evolved from a conceptual framework into a powerful and versatile technology for controlling cellular processes with light.
Xiao Duan, Mo Zhu, Shiqiang Gao
doaj   +1 more source