Results 41 to 50 of about 78,413 (264)

Emerging Lysosomal Functions for Photoreceptor Cell Homeostasis and Survival

Cells, 2021
Lysosomes are membrane-bound cell organelles that respond to nutrient changes and are implicated in cell homeostasis and clearance mechanisms, allowing effective adaptation to specific cellular needs.
Manuela Santo, Ivan Conte
doaj   +1 more source

Data from: Pushing the limits of photoreception in twilight conditions: The rod-like cone retina of the deep-sea pearlsides

, 2020
Most vertebrates have a duplex retina comprising two photoreceptor types, rods for dim-light (scotopic) vision and cones for bright-light (photopic) and color vision.
Helvik, Jon Vidar (University of Bergen), de Busserolles, Fanny (University of Queensland), Irigoien, Xabier (King Abdullah University of Science and Technology), Davies, Wayne I. L. (University of Western Australia), Michell, Craig T. (King Abdullah University of Science and Technology), Templin, Rachel M. (University of Queensland), Kaartvedt, Stein (King Abdullah University of Science and Technology), Sullivan, Robert K. P. (University of Queensland), Collin, Shaun P. (University of Western Australia), Cortesi, Fabio (University of Queensland), Mountford, Jessica K. (University of Western Australia), Marshall, Justin (University of Queensland)   +11 more
core   +1 more source

Exposure to the complement C5b-9 complex sensitizes 661W photoreceptor cells to both apoptosis and necroptosis. [PDF]

, 2015
The loss of photoreceptors is the defining characteristic of many retinal degenerative diseases, but the mechanisms that regulate photoreceptor cell death are not fully understood.
Dimitrios Stampoulis, M. Francesca Cordeiro, Williams, JA, Jennifer A. E. Williams, Stampoulis, D, Li Guo, Shi, H, Guo, L, Moss, SE, Francesca Cordeiro, M, Stephen E. Moss, Hui Shi   +11 more
core   +1 more source

Color Discrimination with Broadband Photoreceptors [PDF]

, 2013
SummaryBackgroundColor vision is commonly assumed to rely on photoreceptors tuned to narrow spectral ranges. In the ommatidium of Drosophila, the four types of so-called inner photoreceptors express different narrow-band opsins.
Tanimoto, Hiromu, Garbers, Christian, Tanimoto, H., Wachtler, T., Schnaitmann, C., Schnaitmann, Christopher, Wachtler, Thomas, Garbers, C.   +7 more
core   +1 more source

Morphogenesis of Drosophila pupal photoreceptors.

, 2013
(A) Side view of developing photoreceptors at mid-stage of pupal development. The photoreceptors elongate from distal to proximal (arrow). (B) Cross-section of mid-stage pupal photoreceptors.
Garrett P. League (349581), Sang-Chul Nam (342110), Geng Chen (194556)   +2 more
core   +3 more sources

Gene therapy restores vision in rd1 mice after removal of a confounding mutation in Gpr179 [PDF]

, 2015
The rd1 mouse with a mutation in the Pde6b gene was the first strain of mice identified with a retinal degeneration. However, AAV-mediated gene supplementation of rd1 mice only results in structural preservation of photoreceptors, and restoration of the ...
Bainbridge, James W.B., Rizzi, M, Nishiguchi, KM, James W. B. Bainbridge, Kate Powell, Joana Ribeiro, Duran, Y, Ribeiro, J, Powell, K, Luhmann, UF, Azam, Selina A., Yanai Duran, Rizzi, Matteo, Livia S. Carvalho, Smith, Alexander J., Holthaus, Sophia Martha Kleine, Robin R. Ali, Ulrich F. O. Luhmann, Carvalho, Livia S., Er J. Smith, Koji M. Nishiguchi, Powell, Kate, Matteo Rizzi, Selina A. Azam, Carvalho, LS, Ali, RR, Holthaus, SM, Sophia-martha Kleine Holthaus, Bainbridge, JW, Ali, Robin R.; id_orcid, Luhmann, Ulrich F.O., Duran, Yanai, Azam, SA, Ribeiro, Joana, Smith, AJ, Nishiguchi, Koji M.   +35 more
core   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Novel rodent models for macular research [PDF]

, 2010
BACKGROUND: Many disabling human retinal disorders involve the central retina, particularly the macula. However, the commonly used rodent models in research, mouse and rat, do not possess a macula.
Gesine Huber, Muehlfriedel, Regine, Huber, G., Feng, Yuxi, Seeliger, M., Tanimoto, Naoyuki, Tanimoto Naoyuki, Severin Heynen, Hans-Peter Hammes, Christian Grimm, Feng, Y., Imsand Coni, Imsand, Coni, Muehlfriedel Regine, Susanne C. Beck, Huber, Gesine, Heynen, S., Grimm Christian, Regine Muehlfriedel, Huber Gesine, vom Hagen Franziska, Coni Imsand, Imsand, C., Seeliger Mathias W., Mühlfriedel, R., Peichl, Leo, Mathias W Seeliger, vom Hagen, F., Mühlfriedel, Regine, Tanimoto, N., Heynen Severin, Hammes, Hans-Peter, Seeliger, Mathias W, Beck Susanne C., Seeliger, Mathias W., Peichl Leo, Yuxi Feng, Peichl, L., Beck, Susanne C; https://orcid.org/, Grimm, C., Feng Yuxi, Mathias W. Seeliger, Leo Peichl, Franziska vom Hagen, Grimm, Christian, Grimm, Christian; https://orcid.org/, vom Hagen, Franziska, Beck, S., Beck, Susanne Christiane, Hammes Hans-Peter, Susanne C Beck, Naoyuki Tanimoto, Hammes, H., Heynen, Severin   +53 more
core   +2 more sources

Light‐Induced Field‐Tunneling Synapses in Solution‐Processed Van Der Waals Heterostructures for Scalable, Retina‐Inspired Optical Sensing

Advanced Functional Materials, EarlyView.
A scalable, solution‐processed WSe2/ZrO2‐x van der Waals heterostructure realizes a light‐induced field‐tunneling synapse (LIFTS) that activates exclusively under bright illumination, emulating the photopic adaptation of the human retina at the device level.
Kijeong Nam, Jihyun Kim, Soobeen Ji, In Soo Kim, Sejin Kim, Eungseon Yeon, Do Kyung Hwang, Iva Plutnarová, Zdeněk Sofer, Sang Min Won, Joohoon Kang   +10 more
wiley   +1 more source

An Adaptive Inhibitory WSe2 Transistor for Retinomorphic In‐Sensor Image Processing

Advanced Functional Materials, EarlyView.
Conventional retinomorphic devices typically require deliberate gate‐bias tuning for each illumination condition. In this paper, we demonstrate an adaptive inhibitory WSe2 transistor that uses photo‐induced regime shift between the subthreshold and accumulation modes to achieve decision‐free, intensity‐adaptive image processing within a single pixel ...
Juhwan Baek, Junhwa Oh, Hyeonjung Kim, Minsik Park, Haein Cho, Jin Young Park, Hyeonchang Son, Taeyun Kim, Sung‐Un An, Yamin Zhang, Hyeon‐Jin Shin, Seyong Oh, Dong‐Ho Kang   +12 more
wiley   +1 more source