Results 21 to 30 of about 108,777 (309)

Photoreceptor processing speed and input resistance changes during light adaptation correlate with spectral class in the bumblebee, Bombus impatiens.

open access: yesPLoS ONE, 2011
Colour vision depends on comparison of signals from photoreceptors with different spectral sensitivities. However, response properties of photoreceptor cells may differ in ways other than spectral tuning. In insects, for example, broadband photoreceptors,
Peter Skorupski, Lars Chittka
doaj   +1 more source

Sphingolipids as emerging mediators in retina degeneration [PDF]

open access: yes, 2019
The sphingolipids ceramide (Cer), sphingosine-1-phosphate (S1P), sphingosine (Sph), and ceramide-1-phosphate (C1P) are key signaling molecules that regulate major cellular functions.
Prado Spalm, Facundo Heber   +3 more
core   +1 more source

Retinal pigment epithelium extracellular vesicles are potent inducers of age‐related macular degeneration disease phenotype in the outer retina

open access: yesJournal of Extracellular Vesicles, 2022
Age‐related macular degeneration (AMD) is a leading cause of blindness. Vision loss is caused by the retinal pigment epithelium (RPE) and photoreceptors atrophy and/or retinal and choroidal angiogenesis.
Marzena Kurzawa‐Akanbi   +28 more
doaj   +1 more source

Cis-regulatory basis of sister cell type divergence in the vertebrate retina [PDF]

open access: yes, 2019
Multicellular organisms evolved via repeated functional divergence of transcriptionally related sister cell types, but the mechanisms underlying sister cell type divergence are not well understood.
Corbo, Joseph C   +4 more
core   +3 more sources

Early stages of retinal development depend on Sec13 function [PDF]

open access: yes, 2013
Summary ER-to-Golgi transport of proteins destined for the extracellular space or intracellular compartments depends on the COPII vesicle coat and is constitutive in all translationally active cells.
Cavodeassi, Florencia   +3 more
core   +3 more sources

OTX2 represses sister cell fate choices in the developing retina to promote photoreceptor specification

open access: yeseLife, 2020
During vertebrate retinal development, subsets of progenitor cells generate progeny in a non-stochastic manner, suggesting that these decisions are tightly regulated.
Miruna Georgiana Ghinia Tegla   +5 more
doaj   +1 more source

P2X7 Is Involved in the Mouse Retinal Degeneration via the Coordinated Actions in Different Retinal Cell Types

open access: yesAntioxidants, 2023
Adenosine triphosphate (ATP) released from dying cells with high concentrations is sensed as a danger signal by the P2X7 receptor. Sodium iodate (NaIO3) is an oxidative toxic agent, and its retinal toxicity has been used as the model of dry age-related ...
Ponarulselvam Sekar   +4 more
doaj   +1 more source

Photoreceptor Inner Segment Morphology in Best Vitelliform Macular Dystrophy [PDF]

open access: yes, 2016
PURPOSE To characterize outer retina structure in best vitelliform macular dystrophy (BVMD) and to determine the effect of macular lesions on overlying and adjacent photoreceptors.
Carroll, Joseph   +7 more
core   +2 more sources

Discordant Responses to MAPK Pathway Stimulation Include Axonal Growths in Adult Drosophila Photoreceptors

open access: yesFrontiers in Molecular Neuroscience, 2018
Wallenda (WND) is the Drosophila member of a conserved family of dual leucine-zipper kinases (DLK) active in both neuronal regeneration and degeneration.
Kirk L. Mecklenburg   +3 more
doaj   +1 more source

Cell therapy with hiPSC-derived RPE cells and RPCs prevents visual function loss in a rat model of retinal degeneration

open access: yesMolecular Therapy: Methods & Clinical Development, 2021
Photoreceptor loss is the principal cause of blindness in retinal degenerative diseases (RDDs). Whereas some therapies exist for early stages of RDDs, no effective treatment is currently available for later stages, and once photoreceptors are lost, the ...
Anna Salas   +10 more
doaj   +1 more source

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