Results 101 to 110 of about 23,776 (285)

Adaptive genomic evolution of opsins reveals that early mammals flourished in nocturnal environments

open access: yesBMC Genomics, 2018
Based on evolutionary patterns of the vertebrate eye, Walls (1942) hypothesized that early placental mammals evolved primarily in nocturnal habitats. However, not only Eutheria, but all mammals show photic characteristics (i.e.
Rui Borges   +5 more
semanticscholar   +1 more source

Spider Eye Development Editing and Silk Fiber Engineering Using CRISPR‐Cas

open access: yesAngewandte Chemie International Edition, EarlyView.
Spiders exhibit unique traits with significant implications for a diversity of fields, and gene editing provides new opportunities for advancing research in these areas. In this study, we developed a CRISPR‐Cas9 protocol for spiders, enabling gene knock‐outs/knock‐ins to study gene function and introduce new phenotypic traits. Abstract CRISPR‐Cas9 gene
Edgardo Santiago‐Rivera   +1 more
wiley   +1 more source

Molecular logic behind the three-way stochastic choices that expand butterfly colour vision. [PDF]

open access: yes, 2016
Butterflies rely extensively on colour vision to adapt to the natural world. Most species express a broad range of colour-sensitive Rhodopsin proteins in three types of ommatidia (unit eyes), which are distributed stochastically across the retina.
Arikawa, Kentaro   +5 more
core   +1 more source

Self-Organized Criticality: A Guide to Water-Protein Landscape Evolution [PDF]

open access: yesarXiv, 2011
We focus here on the scaling properties of small interspecies differences between red cone opsin transmembrane proteins, using a hydropathic elastic roughening tool previously applied to the rhodopsin rod transmembrane proteins. This tool is based on a non-Euclidean hydropathic metric realistically rooted in the atomic coordinates of 5526 protein ...
arxiv  

Specificity of the chromophore-binding site in human cone opsins

open access: yesJournal of Biological Chemistry, 2019
The variable composition of the chromophore-binding pocket in visual receptors is essential for vision. The visual phototransduction starts with the cis-trans isomerization of the retinal chromophore upon absorption of photons. Despite sharing the common
K. Katayama   +7 more
semanticscholar   +1 more source

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz   +9 more
wiley   +1 more source

Three-dimensional scanless holographic optogenetics with temporal focusing (3D-SHOT). [PDF]

open access: yes, 2017
Optical methods capable of manipulating neural activity with cellular resolution and millisecond precision in three dimensions will accelerate the pace of neuroscience research. Existing approaches for targeting individual neurons, however, fall short of
Adesnik, Hillel   +5 more
core   +2 more sources

Multiple trans QTL and one cis-regulatory deletion are associated with the differential expression of cone opsins in African cichlids

open access: yesBMC Genomics, 2018
Dissecting the genetic basis of phenotypic diversity is one of the fundamental goals in evolutionary biology. Despite growing evidence for gene expression divergence being responsible for the evolution of complex traits, knowledge about the proximate ...
Sri Pratima Nandamuri   +2 more
semanticscholar   +1 more source

Soyasaponin and vertical microbial transmission: Maternal effect on the intestinal development and health of early chicks

open access: yesiMeta, EarlyView.
This study investigates the vertical transmission of maternal microbiota in chickens and how it is modulated by maternal soyasaponin supplementation. Using a model spanning the reproductive tract, egg components, and developing chicks, we show that maternal gut and reproductive microbiota, including Bifidobacterium adolescentis (B.
Mingkun Gao   +10 more
wiley   +1 more source

A modified approach to the measurement problem: Objective reduction in the retinal molecule prior to conformational change [PDF]

open access: yesBioSystems 92 (2008) 114-116, 2006
A new analysis of the measurement problem reveals the possibility that collapse of the wavefunction may now take place just before photoisomerization of the rhodopsin molecule in the retinal rods. It is known that when a photon is initially absorbed by the retinal molecule which, along with opsin comprises the rhodopsin molecule, an electron in the ...
arxiv  

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