Results 101 to 110 of about 18,496 (258)
C-opsin Expressing Photoreceptors in Echinoderms [PDF]
Integrative and Comparative Biology, 2013 Today's progress in molecular analysis and, in particular, the increased availability of genome sequences have enabled us to investigate photoreceptor cells (PRCs) in organisms that were formerly inaccessible to experimental manipulation. Our studies of marine non-chordate deuterostomes thus aim to bridge a gap of knowledge regarding the evolution of ...
Esther M, Ullrich-Lüter +2 more
openaire +2 more sources
British Journal of Pharmacology, EarlyView.Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi +10 more
wiley +1 more source
Limits to the salience of ultraviolet: Lessons from colour vision in bees and birds [PDF]
, 2001 Publisher version: http://jeb.biologists.org/content/204/14/2571/F1 ...
Chittka, L, Dyer, AG, Kevan, PG
core
Visual Function Assessment in Geographic Atrophy: A Review
Clinical &Experimental Ophthalmology, EarlyView.ABSTRACT Geographic atrophy (GA) causes significant vision impairment and reduction in vision‐related quality of life. Fundus autofluorescence (FAF) is the gold standard of structural assessment of GA but is a surrogate marker for vision loss, which can be assessed by tests of visual function and functional vision.
Ye Li, Lauren N. Ayton, Adrian T. Fung
wiley +1 more source
Dampening Spontaneous Activity Improves the Light Sensitivity and Spatial Acuity of Optogenetic Retinal Prosthetic Responses [PDF]
, 2016 Retinitis pigmentosa is a progressive retinal dystrophy that causes irreversible visual impairment and blindness. Retinal prostheses currently represent the only clinically available vision-restoring treatment, but the quality of vision returned remains ...
Barrett, John Martin +2 more
core +1 more source
Thermal constraints on in vivo optogenetic manipulations. [PDF]
, 2019 A key assumption of optogenetics is that light only affects opsin-expressing neurons. However, illumination invariably heats tissue, and many physiological processes are temperature-sensitive.
Kreitzer, Anatol C +2 more
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Opsin expression, physiological characterization and identification of photoreceptor cells in the dorsal rim area and main retina of the desert locust, Schistocerca gregaria. [PDF]
, 2014 For compass orientation many insects rely on the pattern of sky polarization, but some species also exploit the sky chromatic contrast. Desert locusts, Schistocerca gregaria, detect polarized light through a specialized dorsal rim area (DRA) in their ...
ARIKAWA Kentaro +6 more
core +2 more sources
Broad-Band Activatable White-Opsin
PLOS ONE, 2015 Currently, the use of optogenetic sensitization of retinal cells combined with activation/inhibition has the potential to be an alternative to retinal implants that would require electrodes inside every single neuron for high visual resolution. However, clinical translation of optogenetic activation for restoration of vision suffers from the drawback ...
Subrata Batabyal +4 more
openaire +5 more sources
Epilepsia, EarlyView.Abstract Objective For over four decades, the substantia nigra pars reticulata (SNr) has been recognized as a critical structure in the modulation of seizure activity. Pharmacological and optogenetic inhibition of the SNr produces robust seizure suppression in a range of seizure models.
Devin Palmer, Patrick A. Forcelli
wiley +1 more source
Restoring Retinal Function in a Mouse Model of Hereditary Blindness [PDF]
, 2005 Moore discusses a new study showing rescue of photoreceptor function using gene and drug therapies in a mouse model of Leber congenital ...
Moore, Tony
core +4 more sources