Results 141 to 150 of about 15,771 (212)
AAV8 vector induced gliosis following neuronal transgene expression
Frontiers in NeuroscienceIntroductionExpression of light sensitive ion channels by selected neurons has been achieved by viral mediated transduction with gene constructs, but for this to have therapeutic uses, for instance in treating epilepsy, any adverse effects of viral ...
Faye McLeod +8 more
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Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder
Journal of Internal Medicine, Volume 299, Issue 3, Page 302-327, March 2026.Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley +1 more source
FishesLight, as one of the most crucial environmental factors, plays an essential role in the growth, physiology, and evolutionary survival of fish. To cope with diverse light conditions in aquatic environments, fish adapt through photosensory systems composed
Zheng Zhang +7 more
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The cellular fate of mutant rhodopsin: quality control, degradation and aggresome formation [PDF]
, 2002 Mutations in the photopigment rhodopsin are the major cause of autosomal dominant retinitis pigmentosa. The majority of mutations in rhodopsin lead to misfolding of the protein.
Cheetham, ME +3 more
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, 2019 Light sensing by tissues distinct from the eye occurs in diverse animal groups, enabling circadian control and phototactic behaviour. Extraocular photoreceptors may also facilitate rapid colour change in cephalopods and lizards, but little is known about
Eacock, A. +5 more
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Outlook Magazine, Autumn 2013 [PDF]
, 2013 https://digitalcommons.wustl.edu/outlook/1190/thumbnail ...
core +1 more source
The Plant Journal, Volume 125, Issue 5, March 2026.Significance Statement This review synthesizes current knowledge of plant hormone transporters across five major protein superfamilies. It links structural classification to transport mechanism and substrate specificity and demonstrates that this structural perspective provides a predictive framework for understanding substrate scope, selectivity ...
Bjørn Lildal Amsinck +4 more
wiley +1 more source
Optimal neuromuscular performance requires motor neuron phosphagen kinases
The Journal of Physiology, Volume 604, Issue 5, Page 2027-2059, 1 March 2026.Abstract figure legend Motor neuron (MN) terminals in fruit flies, mice and humans contain phosphagen kinases, a key enzyme in their energy storage and buffering system. Here we knocked down the primary phosphagen kinase in fruit fly larvae (arginine kinase 1 (ArgK1)) but were surprised to find that MN endurance was unaffected.
Karlis A. Justs +10 more
wiley +1 more source
In silico characterisation and chromosomal localisation of human RRH (peropsin) – implications for opsin evolution [PDF]
, 2003 Bellingham, J, Foster, R G, Wells, D J
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Chemosensory gene expression analysis in the argentine ant, linepithema humile [PDF]
This experiment was conducted to determine expression patterns of a subset of chemosensory genes, including odorant receptors (Ors) and odorant binding proteins (OBPs), in the invasive Argentine ant, Linepithema humile.
Laird, Joseph G.
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