Results 81 to 90 of about 18,496 (258)
Wild-type opsin does not aggregate with a misfolded opsin mutant
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2016 Rhodopsin is the light receptor in photoreceptor cells that plays a central role in phototransduction and photoreceptor cell health. Mutations in rhodopsin are the leading cause of autosomal dominant retinitis pigmentosa (adRP), a retinal degenerative disease. A majority of mutations in rhodopsin cause misfolding and aggregation of the apoprotein opsin.
Megan, Gragg +3 more
openaire +2 more sources
Environmental Toxicology and Chemistry, EarlyView.Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz +9 more
wiley +1 more source
Active state structures of a bistable visual opsin bound to G proteins
Nature CommunicationsOpsins are G protein-coupled receptors (GPCRs) that have evolved to detect light stimuli and initiate intracellular signaling cascades. Their role as signal transducers is critical to light perception across the animal kingdom.
Oliver Tejero +11 more
doaj +1 more source
Cell Reports, 2017 Circadian clocks regulate various aspects of photoreceptor physiology, but their contribution to photoreceptor development and function is unclear. Cone photoreceptors are critical for color vision.
Onkar B. Sawant +6 more
doaj +1 more source
ZBED4, a cone and Müller cell protein in human retina, has a different cellular expression in mouse. [PDF]
, 2011 PurposeZBED4, a protein in cones and Müller cells of human retina, may play important functions as a transcriptional activator of genes expressed in those cells or as a co-activator/repressor of their nuclear hormone receptors.
Akhmedov, Novrouz B +3 more
core +1 more source
Laser &Photonics Reviews, EarlyView.In this work, we investigated the dynamic retinal pathology of glaucoma from onset to late stages through longitudinal in vivo high‐resolution imaging in a silicone oil‐induced ocular hypertension (SOHU) glaucoma mouse model. We developed an optimized adaptive optics two‐photon excitation fluorescence microscopy (AO‐TPEFM) technique for morphological ...
Yiming Fu +6 more
wiley +1 more source
BMC Genomics, 2020 Background Halyomorpha halys (Stål), the brown marmorated stink bug, is a highly invasive insect species due in part to its exceptionally high levels of polyphagy. This species is also a nuisance due to overwintering in human-made structures.
Michael E. Sparks +56 more
doaj +1 more source
Retention of duplicated long-wavelength opsins in mosquito lineages by positive selection and differential expression [PDF]
, 2017 BACKGROUND: Opsins are light sensitive receptors associated with visual processes. Insects typically possess opsins that are stimulated by ultraviolet, short and long wavelength (LW) radiation.
Catherine A. Hill +2 more
core +1 more source
Science, 2019 Evolution![Figure][1] Noctilionoid bats, including the fishing bat shown, have complex mechanisms for eye pigment evolution. PHOTO: CHRISTIAN ZIEGLER/MINDEN PICTURES Opsin genes encode photoreceptor proteins that enable perception of dim light by rod cells and color by cone cells in the eye.
openaire +1 more source
Insect Science, EarlyView.Jewel beetles can discriminate leaf feeding sites and bark oviposition sites based upon the opponent comparison of their blue, green, and red photoreceptor signals. Through this mechanism, green traps resemble leaves, and purple traps resemble bark, explaining their different attractiveness to males and females.
Roger D. Santer, Otar Akanyeti
wiley +1 more source