Results 71 to 80 of about 15,921 (237)

The opsins.

Genome biology, 2005
The photosensitive molecule rhodopsin and its relatives consist of a protein moiety - an opsin - and a non-protein moiety - the chromophore retinal. Opsins, which are G-protein-coupled receptors (GPCRs), are found in animals, and more than a thousand have been identified so far.
openaire   +2 more sources

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Modeling Interference-Free Neuron Spikes with Optogenetic Stimulation [PDF]

, 2019
This paper predicts the ability to externally control the firing times of a cortical neuron whose behavior follows the Izhikevich neuron model. The Izhikevich neuron model provides an efficient and biologically plausible method to track a cortical neuron'
Eckford, Andrew W., Makrakis, Dimitrios, Monabbati, Shayan, Noel, Adam   +3 more
core   +2 more sources

Wild-type opsin does not aggregate with a misfolded opsin mutant

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2016
Rhodopsin is the light receptor in photoreceptor cells that plays a central role in phototransduction and photoreceptor cell health. Mutations in rhodopsin are the leading cause of autosomal dominant retinitis pigmentosa (adRP), a retinal degenerative disease. A majority of mutations in rhodopsin cause misfolding and aggregation of the apoprotein opsin.
Megan, Gragg, Tae Gyun, Kim, Scott, Howell, P S-H, Park   +3 more
openaire   +2 more sources

Material Strategies for Stimulation and Recording in Neural Biocomputing Platforms

Advanced Electronic Materials, EarlyView.
Material strategies enabling stimulation and recording are central to neural biocomputing systems. This review examines how electronic materials govern the encoding of inputs and decoding of outputs in living neural networks. Advances in electrical, optical, and multimodal interfaces highlight emerging design principles for biocomputing platforms ...
Sehong Kang, Junggeon Park, Aryaman Joshi, Rakid Haque, Gyu Weon Hwang, Hyunjoon Kong   +5 more
wiley   +1 more source

Active state structures of a bistable visual opsin bound to G proteins

Nature Communications
Opsins are G protein-coupled receptors (GPCRs) that have evolved to detect light stimuli and initiate intracellular signaling cascades. Their role as signal transducers is critical to light perception across the animal kingdom.
Oliver Tejero, Filip Pamula, Mitsumasa Koyanagi, Takashi Nagata, Pavel Afanasyev, Ishita Das, Xavier Deupi, Mordechai Sheves, Akihisa Terakita, Gebhard F. X. Schertler, Matthew J. Rodrigues, Ching-Ju Tsai   +11 more
doaj   +1 more source

Rapid adaptive evolution of colour vision in the threespine stickleback radiation. [PDF]

, 2016
Vision is a sensory modality of fundamental importance for many animals, aiding in foraging, detection of predators and mate choice. Adaptation to local ambient light conditions is thought to be commonplace, and a match between spectral sensitivity and ...
Heckman, Nancy, Owens, Gregory L, Rennison, Diana J, Schluter, Dolph, Veen, Thor   +4 more
core  

Loss, persistence and reversal of phenotypic traits

Biological Reviews, EarlyView.
ABSTRACT The irreversibility of complex trait loss has long been a tenet of evolutionary biology. However, this idea is increasingly at odds with the numerous documented exceptions across the Tree of Life. We synthesise this growing body of evidence across a diverse array of taxa and traits, exploring the evolutionary conditions that enable ...
Giobbe Forni, Giuseppe Fusco, Filippo Nicolini, Heather Bruce, Andrea Luchetti   +4 more
wiley   +1 more source

Long-wavelength sensitive visual pigments of the guppy (): six opsins expressed in a single individual [PDF]

, 2007
Background The diversity of visual systems in fish has long been of interest for evolutionary biologists and neurophysiologists, and has recently begun to attract the attention of molecular evolutionary geneticists. Several recent studies
Weadick, Cameron J, Chang, Belinda S
core   +2 more sources

Dropping opsin function [PDF]

Science, 2019
Evolution![Figure][1] Noctilionoid bats, including the fishing bat shown, have complex mechanisms for eye pigment evolution. PHOTO: CHRISTIAN ZIEGLER/MINDEN PICTURES Opsin genes encode photoreceptor proteins that enable perception of dim light by rod cells and color by cone cells in the eye.
openaire   +1 more source