Results 21 to 30 of about 7,931 (169)
Calreticulin and Galectin-3 Opsonise Bacteria for Phagocytosis by Microglia
Opsonins are soluble, extracellular proteins, released by activated immune cells, and when bound to a target cell, can induce phagocytes to phagocytose the target cell. There are three known classes of opsonin: antibodies, complement factors and secreted
Tom O. J. Cockram +2 more
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Macrophages are the sentinels for the immune response by particle and pathogen ingestion, degradation, phenotypes alteration, and peptide presentation to T lymphocytes.
Li, Chen
core +1 more source
A Peptide-Fc Opsonin with Pan-Amyloid Reactivity
There is a continuing need for therapeutic interventions for patients with the protein misfolding disorders that result in systemic amyloidosis. Recently, specific antibodies have been employed to treat AL amyloidosis by opsonizing tissue amyloid ...
James S. Foster +11 more
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Phylogenetic lineage and pilus protein Spb1/SAN1518 affect opsonin-independent phagocytosis and intracellular survival of Group B Streptococcus [PDF]
Opsonin-independent phagocytosis of Group B Streptococcus (GBS) is important in defense against neonatal GBS infections. A recent study indicated a role for GBS pilus in macrophage phagocytosis (Maisey et al Faseb J 22 2008 1715-24).
Debasish Chattopadhyay +23 more
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Opsonin-free, real-time imaging of Cryptococcus neoformans capsule during budding
Opsonin-free, real-time imaging of Cryptococcus neoformans capsule during ...
Arturo Casadevall (21382) +6 more
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Protection from Lethal Gram-Positive Infection by Macrophage Scavenger Receptor–Dependent Phagocytosis [PDF]
Infections with gram-positive bacteria are a major cause of morbidity and mortality in humans. Opsonin-dependent phagocytosis plays a major role in protection against and recovery from gram-positive infections.
Silverstein, Samuel C. +11 more
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Summary: Moraxella catarrhalis and nontypeable Haemophilus influenzae (NTHi) are pathogenic bacteria frequently associated with exacerbation of chronic obstructive pulmonary disease (COPD), whose hallmark is inflammatory oxidative stress.
Sonia Nicchi +12 more
doaj +1 more source
The long pentraxin 3 (PTX3) exerts a variety of regulatory functions in acute and chronic tissue inflammation. In particular, PTX3 acts as an opsonin for a variety of pathogens and endogenous particles.
Julian A. Marschner +13 more
doaj +1 more source
Evaluation of a Multivalent Artificial Opsonin to Target and Phagocytose Gram-Negative Bacteria [PDF]
Thesis (Master's)--University of Washington, 2020Hospital-acquired infections (HAIs) are a significant medical concern that must be tackled. HAIs cost the United States billions of dollars annually, and in 2002, were the sixth-leading cause of death [1-2]
Lee, Henry
core

