Results 91 to 100 of about 125,571 (334)
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Bezmiâlem ScienceOptic disc pit is an excavation of the optic disc that usually develops congenital or rarely acquired, mostly located in the inferotemporal part of the disc. It is usually asymptomatic but sometimes might be symptomathic with maculopathy development.
Atilla ŞAHİN +2 more
doaj +1 more source
Güncel Retina Dergisi (Current Retina Journal), 2022 Optic disc pits, optic disc coloboma, morning glory disc anomaly, and peripapillary staphyloma are the leading optic disc anomalies with excavation in the disc. These anomalies can be seen together with some syndromes and in this case, can be evaluated as part of the spectrum of the disease.
openaire +1 more source
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Refractory Central Serous Retinal Detachment in the Presence of Optic Disc Pit – Case Report
OkulistykaAmong congenital optic disc anomalies are megalopapilla, optic nerve aplasia and hypoplasia (de Morsier’s syndrome) and optic disc excavations. The latter are attributed to abnormal fetal fissure’s closure.
Radosław Kaczmarek, Dorota Kaczmarek
doaj +1 more source
Aging and Cancer, EarlyView.Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
Horizontal and vertical optic disc rotation. The Beijing Eye Study.
PLoS ONE, 2017 PurposeTo measure the optic disc rotation around the vertical and horizontal disc axis and to evaluate associations with general and ocular parameters.DesignPopulation-based study.MethodsIn the Beijing Eye Study, 3468 participants (mean age:64.6±9.8 ...
Yuan Yuan Fan +4 more
doaj +1 more source
Ingrowth by photoreceptor axons induces transcription of a retrotransposon in the developing Drosophila brain [PDF]
, 1994 The development of the lamina, the first optic ganglion of the fly visual system, depends on inductive cues from the innervating photoreceptor axons. lacZ expression from a P-element insertion, A72, occurs in the anlage of the lamina coincident with axon
Benzer, Seymour, Mozer, Brian A.
core
Optic Disc Drusen & a Constellation of Other Features of Retinitis Pigmentosa: A Case Report [PDF]
, 2021 Yewande Olubunmi Babalola, AM Baiyeroju
openalex +1 more source