Results 61 to 70 of about 125,571 (334)

Optic Disc Identification Methods for Retinal Images [PDF]

open access: yesComputer Science Journal of Moldova, 2014
Presented are the methods proposed by authors to identify and model the optic disc in colour retinal images. The first three our approaches localized the optic disc in two steps: a) in the green component of RGB image the optic disc area is detected ...
Florin Rotaru   +4 more
doaj  

Pattern of Retinal Nerve Fiber Layer Thickness Loss in Fetal Alcohol Syndrome: A Spectral-Domain Optical Coherence Tomography Analysis

open access: yesActa Médica Portuguesa, 2016
Introduction: Optic disc hypoplasia is a common feature in fetal alcohol syndrome. Thus, we aimed to evaluate the optic disc morphology changes and the peripapillary retinal nerve fiber layer thickness in these patients.
Carlos Menezes   +4 more
doaj   +1 more source

Optical Coherence Tomography Angiography Vessel Density in Healthy, Glaucoma Suspect, and Glaucoma Eyes. [PDF]

open access: yes, 2016
PurposeThe purpose of this study was to compare retinal nerve fiber layer (RNFL) thickness and optical coherence tomography angiography (OCT-A) retinal vasculature measurements in healthy, glaucoma suspect, and glaucoma patients.MethodsTwo hundred sixty ...
Belghith, Akram   +11 more
core  

A GPU-based Evolution Strategy for Optic Disk Detection in Retinal Images [PDF]

open access: yes, 2016
La ejecución paralela de aplicaciones usando unidades de procesamiento gráfico (gpu) ha ganado gran interés en la comunidad académica en los años recientes.
González-Calederón, Guillermo   +1 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Optic disc and cup segmentation for glaucoma detection using Attention U-Net incorporating residual mechanism [PDF]

open access: yesPeerJ Computer Science
Glaucoma is a common eye disease that can cause blindness. Accurate detection of the optic disc and cup disc is crucial for glaucoma diagnosis. Algorithm models based on artificial intelligence can assist doctors in improving detection performance.
Yuanyuan Chen, Yongpeng Bai, Yifan Zhang
doaj   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Acute visual loss and optic disc edema followed by optic atrophy in two cases with deeply buried optic disc drusen: a mimicker of atypical optic neuritis

open access: yesBMC Ophthalmology, 2018
Background Sudden visual loss and optic disc edema caused by optic neuritis (ON) is usually followed by significant visual recovery. However, little or no recovery occurs when the loss is caused by atypical ON, especially in patients with neuromyelitis ...
Mário Luiz R. Monteiro   +3 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

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