Results 41 to 50 of about 434,335 (208)

Junctional sensitivity and atrophy progression rate of geographic atrophy secondary to age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose To determine the relationship between the baseline junctional retinal sensitivity measured with microperimetry and the atrophy progression rate in eyes with geographic atrophy (GA) secondary to age‐related macular degeneration. Methods In this prospective cohort study, patients with GA were examined with fundus autofluorescence (FAF ...
Alexander Kai Thomsen, Jenni Martinez Villarruel Hinnerskov, Miranda Maung, Aubin Mutschler, SriniVas Sadda, Torben Lykke Sørensen   +5 more
wiley   +1 more source

Clinical and morpho-functional results of a second examination of a patient with optic nerve head drusen taken after a long-time interval (27 years)

Российский офтальмологический журнал
Optic disc drusen (ODD) is a bilateral anomaly of the optic nerve, in which hyaline calcified intercellular inclusions appear in the optic disc head area in front of the cribriform plate.
E. E. Ioyleva, E. A. Kabanova, S. I. Belyanina   +2 more
doaj   +1 more source

Clinical manifestations of dual‐gene variants in retinitis pigmentosa

Acta Ophthalmologica, EarlyView.
Abstract Purpose Retinitis pigmentosa (RP) is an inherited retinal disease (IRD), whereby each affected individual typically harbours pathogenic variants in a single causative gene, yet the disorder exhibits marked genetic heterogeneity, with more than 100 genes reported to underlie RP.
Lasse Wolfram, Jan‐Philipp Bodenbender, David A. Merle, Milda Reith, Anton Sonntag, Krunoslav Stingl, Tobias B. Haack, Theresia Zuleger, Bernd Wissinger, Laura Kühlewein, Katarina Stingl, Susanne Kohl   +11 more
wiley   +1 more source

Retinal dystrophies simulating geographic atrophy: A diagnostic challenge

Acta Ophthalmologica, EarlyView.
Abstract Geographic atrophy (GA) is the chronic loss of retinal pigment epithelium, photoreceptors and choriocapillaris, marking the dry late stage of age‐related macular degeneration (AMD). GA prevalence is expected to rise in the upcoming decades. Advanced GA leads to central scotomas, reducing visual acuity and quality of life, potentially resulting
Johanna M. Colijn, Frank G. Holz, Jeroen Pas, Carel Hoyng   +3 more
wiley   +1 more source

Clinical and molecular features of PRCD‐associated retinopathy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To describe the clinical and genetic characteristics of patients with biallelic disease‐causing variants in the PRCD (Progressive Rod‐Cone Degeneration) gene. Methods Multicentre, retrospective cohort study of 19 patients from 13 families across nine reference centres in six countries.
Vasil Kostin, Karolina Kaminska, Marco Cattaneo, Enrico Ambrosini, Carmen Ayuso, Almudena Ávila‐Fernández, Béatrice Bocquet, Luisa Coutinho‐Santos, Benedetto Falsini, Lidia Fernandez‐Caballero Palomeque, Bohdan Kousal, Petra Liskova, Inmaculada Martín‐Mérida, María Juliana Ballesta‐Martínez, Daan Panneman, Susanne Roosing, Isabelle Meunier, José M. Millán, Monika Pankievič, Irene Perea‐Romero, Virginie Peter, Giorgio Placidi, Cristina Santos, Francesca Simonelli, Ana Berta Sousa, Francesco Testa, Marie Vajter, Marianna Weener, Mathieu Quinodoz, Carlo Rivolta, Giacomo Calzetti   +30 more
wiley   +1 more source

Do Optic Disc Drusen Cause Unilateral Nyctalopia

Case Reports in Ophthalmology, 2010
This is a case report of a patient with unilateral nyctalopia in whom ipsilateral optic disc drusen were the only finding despite extensive investigation.
Yi Wei Goh, Alex Buller
doaj   +1 more source

Concurrent macular neovascularization in shallow irregular retinal pigment epithelium elevation phenotypes in age‐related macular degeneration and chronic central serous chorioretinopathy: A systematic review and meta‐analysis

Acta Ophthalmologica, EarlyView.
Abstract This systematic review and meta‐analysis synthesized the reported frequency of concurrent macular neovascularization (MNV) among selected eyes with author‐defined shallow irregular retinal pigment epithelium (RPE) elevations in age‐related macular degeneration (AMD) and chronic central serous chorioretinopathy (CSC).
Mehmet Cem Sabaner, Irem Gunes, Rodrigo Anguita, Elon H. C. van Dijk, Lorenzo Ferro Desideri, Lasse Jørgensen Cehofski, Prithvi Ramtohul, Yousif Subhi   +7 more
wiley   +1 more source

Higher plasma vitamin D levels are not causally associated with less age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose Higher levels of plasma 25‐hydroxyvitamin D have been associated with a lower risk of age‐related macular degeneration (AMD). We investigated observational and potential causal associations of plasma 25‐hydroxyvitamin D with the risk of AMD in two large contemporary population‐based prospective studies and a genetic case–control ...
Sabina O. Beheshti, Michael Larsen, Børge G. Nordestgaard, Shoaib Afzal   +3 more
wiley   +1 more source

Peripapillary hyperreflective ovoid mass-like structures: multimodal imaging and associated diseases

Frontiers in Neurology
Growing evidence has demonstrated that peripapillary hyperreflective ovoid mass-like structures (PHOMS) are novel structures rather than a subtype of optic disc drusen.
Di Xiao, Tsering Lhamo, Yang Meng, Yishuang Xu, Changzheng Chen   +4 more
doaj   +1 more source

Coexistence of optic disc drusen and idiopathic intracranial hypertension in a non-obese female

Journal of Clinical Ophthalmology and Research, 2015
Idiopathic intracranial hypertension (IIHT) is a headache syndrome characterized by elevated intracranial pressure with normal cerebrospinal fluid (CSF) content, normal neuro imaging with optic disc edema.
Pradeep A Venkataramana, Preetham B Patil, Shivabasappa V Koti, Varna Shetty   +3 more
doaj   +1 more source