Results 51 to 60 of about 4,175 (207)

BiOrthoNet: Efficient Retinal OCT Classification Using Direction‐Specific Convolutions

International Journal of Imaging Systems and Technology, Volume 36, Issue 3, May 2026.
ABSTRACT Reliable interpretation of optical coherence tomography (OCT) scans is crucial for the early detection of retinal diseases. Deep learning has emerged as a promising approach for this task; however, many existing models are computationally intensive and fail to exploit the horizontal‐vertical structural organization commonly observed in retinal
Ezzaldeen H. A. Abukhattab, Turgay Batbat   +1 more
wiley   +1 more source

Peripapillary hyperreflective ovoid mass-like structures: multimodal imaging and associated diseases

Frontiers in Neurology
Growing evidence has demonstrated that peripapillary hyperreflective ovoid mass-like structures (PHOMS) are novel structures rather than a subtype of optic disc drusen.
Di Xiao, Tsering Lhamo, Yang Meng, Yishuang Xu, Changzheng Chen   +4 more
doaj   +1 more source

Photodegradable Hydrogels for On‐Demand Modeling of Age‐Related Spatiotemporal ECM Deformation

Small, Volume 22, Issue 27, 14 May 2026.
A light‐tunable PEG hydrogel enables on‐demand, spatiotemporal modeling of drusen‐like ECM bulges in the aging outer retina. By precisely controlling bulge size, the platform reveals how retinal pigment epithelium morphology adapts to topographical changes without disrupting actin cytoskeleton or polarity, effectively mimicking early ageing before ...
Felix Reul, Cédric Bergerbit, Iulia Scarlat, Teodora Piskova, Vasudha Turuvekere Krishnamurthy, Aleksandra N. Kozyrina, Stacy Lok Sze Yam, Laura De Laporte, Jacopo Di Russo   +8 more
wiley   +1 more source

The m.14484T>C MT‐ND6 Mutation Presenting with a Hereditary Spastic‐Paraparesis Phenotype

Movement Disorders Clinical Practice, EarlyView.
Gabriel Amorelli, Christelle Nilles, Gerald Pfeffer, Matthew Joel, Davide Martino   +4 more
wiley   +1 more source

Neovascular age‐related macular degeneration without drusen

Acta Ophthalmologica, Volume 104, Issue 3, Page e300-e311, May 2026.
Abstract Purpose To describe the clinical characteristics and 1‐year follow‐up of patients with neovascular AMD (nAMD) without drusen in either eye. Methods This is a multicentre retrospective cohort study in three tertiary referral centres in The Netherlands. We included patients of 55 years or older with nAMD in one or both eyes, without the presence
Marc J. Sirks, Elon H. C. van Dijk, Husein Ghalayini, Somayeh Bazdar, WeiFeng Yu, Suzanne Yzer, José P. Martinez Ciriano, Reinier O. Schlingemann, Roselie M. H. Diederen, Camiel J. F. Boon   +9 more
wiley   +1 more source

Bilateral Optic Disc Drusen in an Adolescent Female: A Case Report

Nigerian Journal of Medicine
Optic disc drusen (ODD) are calcified deposits within the optic nerve head, usually buried and uncalcified in young patients, and present as pseudopapilloedema, therefore, posing a diagnostic challenge.
Mary Oheobe Ugalahi, Oluwole Iyiola Majekodunmi, Steve Oluwaseun Adebusoye, Tunji Sunday Oluleye   +3 more
doaj   +1 more source

Characterization of retinal pigment epithelium layer in healthy and diseased retinas with high‐resolution adaptive optics transscleral flood illumination imaging

Acta Ophthalmologica, Volume 104, Issue 3, Page e277-e291, May 2026.
Abstract Purpose The retinal pigment epithelium (RPE) is critical in the pathophysiology of retinal diseases, such as age‐related macular degeneration. Adaptive optics transscleral flood illumination (AO‐TFI) offers rapid, detailed morphometric characterization of the RPE layer.
Leila Sara Eppenberger, Safa Mohanna, Sohrab Ferdowsi, Sonja Simon‐Zoula, Oliver Pfäffli, Christoph Amstutz, Lucas M. Bachmann, Michael A. Thiel, Martin K. Schmid   +8 more
wiley   +1 more source

Intraocular Metastasis: Differential Diagnosis and Management

Clinical &Experimental Ophthalmology, Volume 54, Issue 3, Page 382-397, April 2026.
ABSTRACT Intraocular metastases represent the most common type of malignant intraocular tumour in adults. These commonly affect the choroid but can also involve the iris, ciliary body, retina, vitreous, optic disc or lens. Breast and lung cancer are the most common origins of intraocular metastases.
Genovefa Μachairoudia, Dimitrios Kazantzis, Guy S. Negretti, Mandeep S. Sagoo   +3 more
wiley   +1 more source

Overproduction of 42 Amino Acids Long Amyloid Beta Leads to Activation of Secretory Autophagy and Development of Drusen‐Like Structures Originating From Retinal Pigment Epithelium

The FASEB Journal, Volume 40, Issue 5, 15 March 2026.
The role of 42 amino acids long amyloid beta (Aβ) in the retinal pigment epithelium (RPE) was investigated using 5xFAD mice model overproducing Aβ. The RPE cells of 5xFAD mice showed increased oxidative stress, accumulation of autophagy‐destined proteins, increased expression of secretory autophagy markers, and increase in epithelial‐to‐mesenchymal ...
Johanna Ruuth, Toni Tamminen, Elisa Toropainen, Heikki Tanila, Juha M. T. Hyttinen, Tarja Malm, Kai Kaarniranta, Ali Koskela   +7 more
wiley   +1 more source

Healthy Dietary Patterns and Risk of Major Eye Diseases: Evidence From Nationally Population‐Based Data and Bibliometric Analysis

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
This study found that higher adherence to HEI‐2020, DASH, and Mediterranean dietary patterns was associated with a lower prevalence of selected major eye diseases. ABSTRACT The associations between dietary patterns and major eye diseases remain incompletely understood.
Kunhong Xiao, Jiajia Gao, Yiyan Zhang, Ruiye Chen, Yuqing Wang, Chufeng Gu, Jiahao Liu, Yan Huang, Li Li   +8 more
wiley   +1 more source